Effects of Substitutions at the 4′ and 2 Positions on the Bioactivity of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine

Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA

(2013) Eleftherios Michailidis et al.   Retrovirology

HIV-1 Antiretroviral Drug Therapy

(2013) E. J. Arts et al.   Cold Spring Harbor Perspectives in Medicine

Response of Simian Immunodeficiency Virus to the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-DeoxyadenosineIn VitroandIn Vivo

(2012) Michael Murphey-Corb et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2′-deoxy nucleoside analogues

(2012) Orrette R. Wauchope et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antiviral therapies: Focus on hepatitis B reverse transcriptase

(2012) Eleftherios Michailidis et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

4′-C-Methyl-2′-Deoxyadenosine and 4′-C-Ethyl-2′-Deoxyadenosine Inhibit HIV-1 Replication

(2011) B. Christie Vu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine Indicates a Low Potential for Host Toxicity

(2011) Christal D. Sohl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tricyclic 2′-C-Modified Nucleosides as Potential Anti-HCV Therapeutics

(2010) Orrette R. Wauchope et al.   ORGANIC LETTERS

Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase

(2010) Kamalendra Singh et al.   Viruses-Basel

Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action

(2009) Caroline Bazzoli et al.   CLINICAL PHARMACOKINETICS

Mechanism of Inhibition of HIV-1 Reverse Transcriptase by 4′-Ethynyl-2-fluoro-2′-deoxyadenosine Triphosphate, a Translocation-defective Reverse Transcriptase Inhibitor

(2009) Eleftherios Michailidis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HCV drug discovery aimed at viral eradication

(2009) R. F. Schinazi et al.   JOURNAL OF VIRAL HEPATITIS

Contrasting Behavior of Conformationally Locked Carbocyclic Nucleosides of Adenosine and Cytidine as Substrates for Deaminases

(2009) Victor E. Marquez et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

2′-Deoxy-4′-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants

(2008) Atsushi Kawamoto et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

(2008) Stefan G. Sarafianos et al.   JOURNAL OF MOLECULAR BIOLOGY

Fluorine Substituted Adenosines As Probes of Nucleobase Protonation in Functional RNAs

(2008) Ian T. Suydam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase

(2008) Luis Menéndez-Arias   VIRUS RESEARCH