Structure-Antifungal Activity Relationships of Polyene Antibiotics of the Amphotericin B Group

Amphotericin primarily kills yeast by simply binding ergosterol

(2012) K. C. Gray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei

(2011) Trygve Brautaset et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities

(2011) D. S. Palacios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical modification of antifungal polyene macrolide antibiotics

(2011) S E Solovieva et al.   RUSSIAN CHEMICAL REVIEWS

Synthesis and study of the antifungal activity of new mono- and disubstituted derivatives of a genetically engineered polyene antibiotic 28,29-didehydronystatin A1 (S44HP)

(2009) Maria N Preobrazhenskaya et al.   JOURNAL OF ANTIBIOTICS

Microbial drug discovery: 80 years of progress

(2009) Arnold L Demain et al.   JOURNAL OF ANTIBIOTICS

Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei

(2008) Trygve Brautaset et al.   CHEMISTRY & BIOLOGY

Biosynthetic Engineering of Polyene Macrolides Towards Generation of Improved Antifungal and Antiparasitic Agents

(2008) Patrick Caffrey et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Chemical Modification and Biological Evaluation of New Semisynthetic Derivatives of 28,29-Didehydronystatin A1(S44HP), a Genetically Engineered Antifungal Polyene Macrolide Antibiotic

(2008) Maria N. Preobrazhenskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY