Article
Biochemical Research Methods
Kuo-Wei Hsu, Wen-Bin Lee, Huey-Ling You, Mel S. Lee, Gwo-Bin Lee
Summary: Urinary tract infections are common in females, posing risks to kidney function and often requiring broad-spectrum antibiotics. The rise of drug-resistant strains has led to high recurrence rates, emphasizing the need for accurate antibiotic selection. A newly developed portable system allows for rapid and precise measurement of antibiotic sensitivity in urine samples, offering promise for future personalized medicine.
Article
Infectious Diseases
Ga Eun Park, Jae-Hoon Ko, Sun Young Cho, Hee Jae Huh, Jin Yang Baek, Kwan Soo Ko, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck
Summary: This study evaluated the clinical outcomes of bacteremic urinary tract infection patients caused by Enterobacteriaceae with reduced susceptibility to ciprofloxacin. Results showed that reduced ciprofloxacin susceptibility did not lead to poorer clinical outcomes, suggesting the need for further evaluation to guide the selection of appropriate antibiotics for urinary tract infections.
Article
Public, Environmental & Occupational Health
Karyom Djim-Adjim-Ngana, Brunel W. Mbiakop, Leila A. Oumar, Hermann Munshili L. Njifon, Cedric Tchinda Fossi, Elisee L. Embolo Enyegue, Mohamed Mouiche M. Mouliom, Simeon P. Fodouop Chegaing, Louis Deweerdt, Nicolas Njintang Yanou, Julien A. Nguinkal
Summary: This study retrospectively determined the prevalence of multi-drug resistant ESBL strains isolated from UTIs in Northern Cameroon and evaluated the effectiveness of the ATB UR Gallery of BioMerieux in diagnosing ESBL-E. The study found high levels of drug resistance and diverse patterns of antibiotic resistance in ESBL-E strains. These findings emphasize the importance of implementing appropriate treatment guidelines and antimicrobial stewardship measures to prevent the spread and impact of multi-drug resistant strains on public health.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Pediatrics
May Albarrak, Mona Al Dabbagh, Hilal Al Hashami, Omar Alzomor, Ghassan Ghatasheh, Nervana Habashy, Ashraf Hassanien, Andres Perez-Lopez
Summary: This study aims to review the published literature on pediatric urinary tract infections (UTIs) in the Gulf Cooperation Council (GCC) countries, including risk factors, etiology, antimicrobial susceptibility, and treatment. UTIs are common bacterial infections in children and can be acquired in healthcare or community settings.
FRONTIERS IN PEDIATRICS
(2023)
Article
Microbiology
Funke F. Assouma, Haziz Sina, Tomabu Adjobimey, Agossou Damien Pacome Noumavo, Akim Socohou, Bawa Boya, Ange D. Dossou, Lauriane Akpovo, Basile Boni Saka Konmy, Jacques F. Mavoungou, Adolphe Adjanohoun, Lamine Baba-Moussa
Summary: The study aimed to characterize the resistance profile and virulence of Enterobacteriaceae strains causing urinary tract infections (UTIs) in Benin. A total of 390 UTI urine samples were collected, and Enterobacteriaceae strains were identified and tested for antibiotic susceptibility, biofilm production, and ESBL production. Multiplex PCR was used to detect uro-virulence genes. The results revealed a high prevalence of Enterobacteriaceae strains, with E. coli being the most frequently isolated species.
Article
Infectious Diseases
Michaela Tutone, Truls E. Bjerklund Johansen, Tommaso Cai, Shazad Mushtaq, David M. Livermore
Summary: Urinary tract infections (UTIs) are common worldwide, especially among women. A study investigated the susceptibility of current urinary isolates to fosfomycin and other antibiotics, and found that Escherichia coli was the most common uropathogen isolated and highly susceptible to fosfomycin, nitrofurantoin, and mecillinam.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
(2022)
Article
Microbiology
Cheng-Yen Kao, Yen-Zheng Zhang, Deng-Chi Yang, Pek Kee Chen, Ching-Hao Teng, Wei-Hung Lin, Ming-Cheng Wang
Summary: This study investigated the characteristics of host and bacteria in recurrent urinary tract infections (RUTI) caused by genetically identical or different Escherichia coli strains. The results showed that E. coli strains in RUTI were more virulent and important for the development of RUTI in patients who were younger, without anatomical/functional defects or immune dysfunction. Prior antibiotic therapy, especially fluoroquinolones, could induce subsequent antimicrobial resistance in genetically highly-related E. coli RUTI.
Article
Microbiology
Kanika Bhargava, Gopal Nath, Amit Bhargava, Ritu Kumari, G. K. Aseri, Neelam Jain
Summary: Urinary tract infection (UTI) is a common infectious disease that affects men and women. This study investigated the prevalence and antibiotic susceptibility of uropathogens isolated from UTI patients in the eastern part of Northern India. The findings revealed a high prevalence of multidrug-resistant (MDR) pathogens, emphasizing the importance of proper management and antibiotic policy based on the local susceptibility patterns.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Thembekile Zwane, Liliwe Shuping, Olga Perovic
Summary: In South Africa, community-acquired UTIs are predominantly caused by E. coli, with high susceptibility to first-line antibiotics such as gentamicin and nitrofurantoin. This study provides an indication of antimicrobial resistance levels in the region.
Article
Chemistry, Analytical
Katarina Rebrosova, Silvie Bernatova, Martin Siler, Magdalena Uhlirova, Ota Samek, Jan Jezek, Veronika Hola, Filip Ruzicka, Pavel Zemanek
Summary: Urinary tract infections are among the most common infections worldwide. This study demonstrates that Raman spectroscopy can be used as a rapid diagnostic tool to differentiate causative agents and determine antimicrobial susceptibility. It holds great potential for clinical diagnostics in the future.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biology
Ann A. Elshamy, Sarra E. Saleh, Mohammad Y. Alshahrani, Khaled M. Aboshanab, Mohammad M. Aboulwafa, Nadia A. Hassouna
Summary: Gram-negative bacteria are common causes of urinary tract infections (UTIs) and can exhibit resistance to carbapenems. This study found a relatively high rate of carbapenem resistance among Gram-negative bacteria causing UTIs in Cairo, Egypt, with the ability for this resistance to be horizontally transferred to other bacterial hosts.
Review
Infectious Diseases
Faiza Morado, Darren W. Wong
Summary: Urinary tract infection is a common bacterial infection with challenges in diagnosis. To limit unnecessary testing and antibiotic use, various diagnostic stewardship initiatives involving multidisciplinary approaches and education of healthcare providers are effective in decreasing inappropriate testing and prescribing.
Article
Immunology
Wei-Hung Lin, Ming-Cheng Wang, Po-Yao Liu, Po-Shun Chen, Li-Li Wen, Ching-Hao Teng, Cheng-Yen Kao
Summary: Age-related differences in host characteristics may influence the virulence factors and antimicrobial susceptibility of uropathogenic Escherichia coli. In this study, E.coli isolated from the 0-3 age group exhibited the highest frequencies of virulence factors, with phylogenetic group B2 being dominant. As host age increased, the isolated E. coli strains showed increased resistance to antimicrobial agents.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Infectious Diseases
Vitus Silago, Nyambura Moremi, Majigo Mtebe, Erick Komba, Salim Masoud, Fauster X. Mgaya, Mariam M. Mirambo, Helmut A. Nyawale, Stephen E. Mshana, Mecky Isaac Matee
Summary: Empirical treatment of urinary tract infections without laboratory confirmation is common in low-income countries, leading to unnecessary and ineffective antibiotic prescriptions and the emergence of antimicrobial resistance. This study examined the antibiogram of uropathogens causing community-acquired UTIs in Tanzanian outpatients, highlighting the need to strengthen laboratory diagnostics for antimicrobial resistance surveillance.
Article
Microbiology
Wei-Hung Lin, Yen-Zhen Zhang, Po-Yao Liu, Po-Shun Chen, Shining Wang, Pei-Yun Kuo, Tran Thi Dieu Thuy, Tran Thi Thuy Duong, Li-Li Wen, Yi-Hsien Hsieh, Ming-Cheng Wang, Cheng-Yen Kao
Summary: This study compared the characteristics of E. coli isolated from UTI patients in 2009-2010 and 2020, finding that isolates in 2020 were more susceptible to antibiotics and showed changes in the prevalence of certain virulence factors compared to those in 2009-2010.
Article
Obstetrics & Gynecology
Dimitrios Zacharakis, Themos Grigoriadis, Eleni Pitsouni, Kostas Kypriotis, Nikistratos Vogiatzis, Stavros Athanasiou
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2018)
Review
Geriatrics & Gerontology
Eleni Pitsouni, Themos Grigoriadis, Matthew E. Falagas, Stefano Salvatore, Stavros Athanasiou
Article
Urology & Nephrology
Dimitrios Zacharakis, Themos Grigoriadis, Charis Bourgioti, Eleni Pitsouni, Athanasios Protopapas, Lia A. Moulopoulos, Stavros Athanasiou
NEUROUROLOGY AND URODYNAMICS
(2018)
Review
Obstetrics & Gynecology
T. Grigoriadis, S. Athanasiou
Article
Obstetrics & Gynecology
R. Flint, L. Cardozo, T. Grigoriadis, A. Rantell, E. Pitsouni, S. Athanasiou
Article
Obstetrics & Gynecology
S. Athanasiou, E. Pitsouni, T. Grigoriadis, G. Michailidis, A. Tsiveleka, A. Rodolakis, D. Loutradis
Article
Obstetrics & Gynecology
Stavros Athanasiou, Dimitrios Zacharakis, Christos Kalantzis, Athanasios Protopapas, Ioannis Chatzipapas, Themos Grigoriadis
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2020)
Letter
Urology & Nephrology
Stavros Athanasiou, Eleni Pitsouni, Stavroula Antonopoulou, Dimitris Zacharakis, Stefano Salvatore, Matthew E. Falagas, Themos Grigoriadis
NEUROUROLOGY AND URODYNAMICS
(2020)
Article
Urology & Nephrology
Maurizio Serati, Andrea Braga, Giorgio Caccia, Marco Torella, Fabio Ghezzi, Stefano Salvatore, Stavros Athanasiou
NEUROUROLOGY AND URODYNAMICS
(2020)
Article
Obstetrics & Gynecology
S. Athanasiou, E. Pitsouni, L. Cardozo, D. Zacharakis, E. Petrakis, D. Loutradis, T. Grigoriadis
Summary: This study found that intravaginal Er:YAG laser treatment is not effective for managing anterior and/or posterior vaginal compartment prolapse.
Review
Obstetrics & Gynecology
Stavros Athanasiou, Eleni Pitsouni, Themos Grigoriadis, Dimitris Zacharakis, Stefano Salvatore, Maurizio Serati
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
(2020)
Article
Obstetrics & Gynecology
Stavros Athanasiou, Dimitrios Zacharakis, Themos Grigoriadis, Theodoros Papalios, Eleni Pitsouni, Dimitrios Valsamidis, Sofia Hadzillia
INTERNATIONAL UROGYNECOLOGY JOURNAL
(2020)
Article
Obstetrics & Gynecology
S. Salvatore, E. Pitsouni, T. Grigoriadis, D. Zacharakis, G. Pantaleo, M. Candiani, S. Athanasiou
Summary: In postmenopausal women with genitourinary syndrome of menopause, CO2 laser treatment was found to be more effective in improving dryness, dyspareunia, and sexual dysfunction compared to sham treatments.
Review
Urology & Nephrology
Dimitrios Zacharakis, Anastasia Prodromidou, Athanasios Douligeris, Sofia Hadzilia, Nikolaos Kathopoulis, Stavros Athanasiou, Themos Grigoriadis
Summary: Local anesthesia (LA) with or without sedation is a safe and efficient alternative anesthetic technique for urogynecological procedures, with improved pain scores in up to 18 hours postoperatively especially in patients with stress urinary incontinence (SUI).
NEUROUROLOGY AND URODYNAMICS
(2021)
Review
Obstetrics & Gynecology
S. Salvatore, A. F. Ruffolo, C. Phillips, S. Athanasiou, L. Cardozo, M. Serati, EUGA Working Grp
Summary: Vulvovaginal atrophy (VVA) is a chronic progressive condition related to decreased estrogen levels during menopause. Genitourinary syndrome of menopause (GSM) is a more accurate and accepted term for VVA. First-line therapy includes lubricants or moisturizers, with low-dose vaginal estrogens as an option. Laser therapy has been shown to be effective and safe for treating GSM symptoms in postmenopausal women and breast cancer survivors.