Pharmacokinetics, Pharmacodynamics, and Tolerability of GS-9851, a Nucleotide Analog Polymerase Inhibitor, following Multiple Ascending Doses in Patients with Chronic Hepatitis C Infection
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Title
Pharmacokinetics, Pharmacodynamics, and Tolerability of GS-9851, a Nucleotide Analog Polymerase Inhibitor, following Multiple Ascending Doses in Patients with Chronic Hepatitis C Infection
Authors
Keywords
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Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 57, Issue 3, Pages 1209-1217
Publisher
American Society for Microbiology
Online
2012-12-22
DOI
10.1128/aac.01263-12
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Note: Only part of the references are listed.- Pharmacokinetics, Safety, and Tolerability of GS-9851, a Nucleotide Analog Polymerase Inhibitor for Hepatitis C Virus, following Single Ascending Doses in Healthy Subjects
- (2012) Jill Denning et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- Safety and efficacy of treatment for chronic hepatitis C with a focus on pegylated interferons: the backbone of therapy today and in the future
- (2011) Peter Ferenci Expert Opinion On Drug Safety
- An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases
- (2011) Marc G. Ghany et al. HEPATOLOGY
- PSI-7851, a Pronucleotide of -D-2'-Deoxy-2'-Fluoro-2'-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication
- (2010) A. M. Lam et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- New HCV therapies on the horizon
- (2010) J. Vermehren et al. CLINICAL MICROBIOLOGY AND INFECTION
- Emerging therapies for hepatitis C virus
- (2010) Aybike Birerdinc et al. EXPERT OPINION ON EMERGING DRUGS
- Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977
- (2010) Eisuke Murakami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery of a β-d-2′-Deoxy-2′-α-fluoro-2′-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus
- (2010) Michael J. Sofia et al. JOURNAL OF MEDICINAL CHEMISTRY
- Experimental models for hepatitis C viral infection
- (2009) Andre Boonstra et al. HEPATOLOGY
- HCV drug discovery aimed at viral eradication
- (2009) R. F. Schinazi et al. JOURNAL OF VIRAL HEPATITIS
- Development of Intergenotypic Chimeric Replicons To Determine the Broad-Spectrum Antiviral Activities of Hepatitis C Virus Polymerase Inhibitors
- (2008) K. J. Herlihy et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479
- (2008) S. Ali et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Resistance mechanisms in HCV: from evolution to intervention
- (2008) Arthur Y Kim et al. Expert Review of Anti-Infective Therapy
- Expert opinion on the treatment of patients with chronic hepatitis C
- (2008) S. Zeuzem et al. JOURNAL OF VIRAL HEPATITIS
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