Broad Phenotypic Cross-Resistance to Elvitegravir in HIV-Infected Patients Failing on Raltegravir-Containing Regimens

Elvitegravir overcomes resistance to raltegravir induced by integrase mutation Y143

(2011) Mathieu Métifiot et al.   AIDS

Plasma Raltegravir Exposure Influences the Antiviral Activity and Selection of Resistance Mutations

(2011) Carolina Garrido et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

(2011) Kendra E. Hightower et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Long‐Term Efficacy and Safety of Raltegravir Combined with Optimized Background Therapy in Treatment‐Experienced Patients with Drug‐Resistant HIV Infection: Week 96 Results of the BENCHMRK 1 and 2 Phase III Trials

(2010) Roy T. Steigbigel et al.   CLINICAL INFECTIOUS DISEASES

Raltegravir Versus Efavirenz Regimens in Treatment-Naive HIV-1–Infected Patients: 96-Week Efficacy, Durability, Subgroup, Safety, and Metabolic Analyses

(2010) Jeffrey L Lennox et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors

(2010) Francesca Ceccherini-Silberstein et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The HIV-1 Integrase Mutations Y143C/R Are an Alternative Pathway for Resistance to Raltegravir and Impact the Enzyme Functions

(2010) Sandrine Reigadas et al.   PLoS One

Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo

(2009) O. Delelis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Decrease in Serial Prevalence of Coinfection with Hepatitis C Virus among HIV‐Infected Patients in Spain, 1997–2006

(2009) Santiago Pérez Cachafeiro et al.   CLINICAL INFECTIOUS DISEASES

Integrase variability and susceptibility to HIV integrase inhibitors: impact of subtypes, antiretroviral experience and duration of HIV infection

(2009) C. Garrido et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A combined genotypic and phenotypic human immunodeficiency virus type 1 recombinant virus assay for the reverse transcriptase and integrase genes

(2009) Kurt Van Baelen et al.   JOURNAL OF VIROLOGICAL METHODS

HIV-1 integrase polymorphisms are associated with prior antiretroviral drug exposure

(2009) Sebastiaan J van Hal et al.   Retrovirology

Subgroup and Resistance Analyses of Raltegravir for Resistant HIV-1 Infection

(2008) David A. Cooper et al.   NEW ENGLAND JOURNAL OF MEDICINE