UC781 Microbicide Gel Retains Anti-HIV Activity in Cervicovaginal Lavage Fluids Collected following Twice-Daily Vaginal Application

First Phase 1 Double-Blind, Placebo-Controlled, Randomized Rectal Microbicide Trial Using UC781 Gel with a Novel Index of Ex Vivo Efficacy

(2011) Peter A. Anton et al.   PLoS One

Female Genital Tract Secretions and Semen Impact the Development of Microbicides for the Prevention of HIV and Other Sexually Transmitted Infections

(2010) Betsy C. Herold et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Approaches to improve the stability of the antiviral agent UC781 in aqueous solutions

(2010) Festo Damian et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

(2010) Sheena McCormack et al.   LANCET

Postcoital Bioavailability and Antiviral Activity of 0.5% PRO 2000 Gel: Implications for Future Microbicide Clinical Trials

(2010) Marla J. Keller et al.   PLoS One

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Pharmaceutical development of microbicide drug products

(2009) David R. Friend   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Comparative Evaluation of Virus Transmission Inhibition by Dual-Acting Pyrimidinedione Microbicides Using the Microbicide Transmission and Sterilization Assay

(2008) K. M. Watson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of Gammaretroviruses Constitutively Released from Cell Lines Used for Human Immunodeficiency Virus Research

(2008) Y. Takeuchi et al.   JOURNAL OF VIROLOGY

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

(2008) Stephanie Skoler-Karpoff et al.   LANCET

SAVVY Vaginal Gel (C31G) for Prevention of HIV Infection: A Randomized Controlled Trial in Nigeria

(2008) Paul J. Feldblum et al.   PLoS One

A Randomized Six-Day Safety Study of an Antiretroviral Microbicide Candidate UC781, a Non-Nucleoside Reverse Transcriptase Inhibitor

(2008) Jill L. Schwartz et al.   SEXUALLY TRANSMITTED DISEASES