Design and Evaluation of Primaquine-Artemisinin Hybrids as a Multistage Antimalarial Strategy

Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

(2011) Laurent Dembele et al.   PLoS One

A Research Agenda to Underpin Malaria Eradication

(2011) Pedro L. Alonso et al.   PLOS MEDICINE

In Tanzania, Hemolysis after a Single Dose of Primaquine Coadministered with an Artemisinin Is Not Restricted to Glucose-6-Phosphate Dehydrogenase-Deficient (G6PD A-) Individuals

(2010) S. A. Shekalaghe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series†

(2010) Jose M. Coterón et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial

(2010) Frank Smithuis et al.   LANCET INFECTIOUS DISEASES

Establishment of an In Vitro Assay for Assessing the Effects of Drugs on the Liver Stages of Plasmodium vivax Malaria

(2010) Rana Chattopadhyay et al.   PLoS One

Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: Design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition

(2009) Rita Capela et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hybrid Drugs for Malaria

(2009) J. Walsh et al.   CURRENT PHARMACEUTICAL DESIGN

New medicines to improve control and contribute to the eradication of malaria

(2009) Timothy N. C. Wells et al.   NATURE REVIEWS DRUG DISCOVERY

Visualisation and Quantitative Analysis of the Rodent Malaria Liver Stage by Real Time Imaging

(2009) Ivo H. J. Ploemen et al.   PLoS One

Host Scavenger Receptor SR-BI Plays a Dual Role in the Establishment of Malaria Parasite Liver Infection

(2008) Cristina D. Rodrigues et al.   Cell Host & Microbe

Primaquine revisited six decades after its discovery

(2008) Nuno Vale et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kinome-Wide RNAi Screen Implicates at Least 5 Host Hepatocyte Kinases in Plasmodium Sporozoite Infection

(2008) Miguel Prudêncio et al.   PLoS Pathogens