4.7 Article

Clinical Carbapenem-Resistant Acinetobacter baylyi Strain Coharboring blaSIM-1 and blaOXA-23 from China

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 55, Issue 11, Pages 5347-5349

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00425-11

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Funding

  1. National Natural Science Foundation of China [NSFC30970113]
  2. Ministry of Health of the People's Republic of China [200802107]
  3. Natural Science Foundation of Zhejiang Province [Y207477]

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bla(SIM-1) and bla(OXA-23) were codetected in clinical carbapenem-resistant Acinetobacter baylyi strain NB09A30. Both of carbapenemase genes were located on a large plasmid (ca. 360 kb). bla(SIM-1) was found as a gene cassette inserted into a class 1 integron identical to that determined in Acinetobacter sp. isolates from South Korea. The genetic structure of bla(OXA-23) in NB09A30 was different from that in the prevalent Acinetobacter baumannii of clonal complex 92 (CC92) from the same hospital.

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