Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 55, Issue 9, Pages 4412-4415Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00365-11
Keywords
-
Categories
Funding
- Vietnam People's Army
- Australian Defense Force
- Vietnam People's Army Department of Military Medicine
- Australian Defense Force International Policy Division
Ask authors/readers for more resources
In 18 male healthy subjects, artesunate (200 mg)-azithromycin (1,500 mg) daily for 3 days was found to be well tolerated, with only mild gastrointestinal disturbances reported. The pharmacokinetic properties of artesunate-azithromycin given in combination are comparable to those of the drugs given alone. Artesunate and its major active metabolite, dihydroartemisinin, are responsible for most of the ex vivo antimalarial activity, with a delayed contribution by azithromycin.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available