In SilicoChildren and the Glass Mouse Model: Clinical Trial Simulations To Identify and Individualize Optimal Isoniazid Doses in Children with Tuberculosis

An Oracle: Antituberculosis Pharmacokinetics-Pharmacodynamics, Clinical Correlation, and Clinical Trial Simulations To Predict the Future

(2010) Jotam Pasipanodya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical and Toxicodynamic Evidence that High-Dose Pyrazinamide Is Not More Hepatotoxic than the Low Doses Currently Used

(2010) J. G. Pasipanodya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

New Susceptibility Breakpoints for First-Line Antituberculosis Drugs Based on Antimicrobial Pharmacokinetic/Pharmacodynamic Science and Population Pharmacokinetic Variability

(2010) T. Gumbo   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Practical, Individualized Dosing: 21st Century Therapeutics and the Clinical Pharmacometrician

(2010) Michael Neely et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Population Modeling and Monte Carlo Simulation Study of the Pharmacokinetics and Antituberculosis Pharmacodynamics of Rifampin in Lungs

(2009) S. Goutelle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics-Pharmacodynamics of Pyrazinamide in a Novel In Vitro Model of Tuberculosis for Sterilizing Effect: a Paradigm for Faster Assessment of New Antituberculosis Drugs

(2009) T. Gumbo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Neutrophils Are the Predominant Infected Phagocytic Cells in the Airways of Patients With Active Pulmonary TB

(2009) Seok-Yong Eum et al.   CHEST

Isoniazid Plasma Concentrations in a Cohort of South African Children with Tuberculosis: Implications for International Pediatric Dosing Guidelines

(2009) Helen McIlleron et al.   CLINICAL INFECTIOUS DISEASES

The In Silico Child: Using Simulation to Guide Pediatric Drug Development and Manage Pediatric Pharmacotherapy

(2009) Stephanie Läer et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Low-dose inhaled versus standard dose oral form of anti-tubercular drugs: Concentrations in bronchial epithelial lining fluid, alveolar macrophage and serum

(2009) S Prakash et al.   Journal of Postgraduate Medicine

A simple in vitro PK/PD model system to determine time–kill curves of drugs against Mycobacteria

(2009) Nageshwar R. Budha et al.   TUBERCULOSIS

Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro

(2008) R. Sauermann et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Paediatric tuberculosis

(2008) Sandra M Newton et al.   LANCET INFECTIOUS DISEASES