Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 52, Issue 5, Pages 1850-1851Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01139-07
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We tested the activity of daptomycin against 76 Listeria monocytogenes isolates from cerebrospinal fluid by broth dilution and Etest methods. For the broth dilution method, the MIC range was 1.0 to 8.0 and the MIC at which 90% of the isolates tested were inhibited (MIC90) was 4.0 mg/liter. For the Etest method, the MIC range was 1.0 to 4.0 and the MIC90, was 4.0 mg/liter. Presently, daptomycin cannot be recommended for the treatment of L. monocytogenes meningitis.
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