Renal Transporters in Drug Development

The UCSF-FDA TransPortal: A Public Drug Transporter Database

(2012) K M Morrissey et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Regulatory Perspectives on Designing Pharmacokinetic Studies and Optimizing Labeling Recommendations for Patients With Chronic Kidney Disease

(2012) Lei Zhang et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Current Understanding of Drug Disposition in Kidney Disease

(2012) Judith Naud et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Drug Transporters in Drug Efficacy and Toxicity

(2011) M.K. DeGorter et al.   Annual Review of Pharmacology and Toxicology

Performance of serum cystatin C versus serum creatinine as a marker of glomerular filtration rate as measured by inulin renal clearance

(2011) Masaru Horio et al.   Clinical and Experimental Nephrology

A Common 5′-UTR Variant in MATE2-K Is Associated With Poor Response to Metformin

(2011) J H Choi et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Age-related Changes in Pharmacodynamics: Focus on Drugs Acting on Central Nervous and Cardiovascular Systems

(2011) Gianluca Trifiro et al.   CURRENT DRUG METABOLISM

Estimation of Glomerular Filtration Rate: What Are the Pitfalls?

(2011) Pierre Fesler et al.   CURRENT HYPERTENSION REPORTS

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels

(2011) Ramzi Shawahna et al.   MOLECULAR PHARMACEUTICS

Performance of Estimated Glomerular Filtration Rate Prediction Equations in Preeclamptic Patients

(2010) Arnold Alper et al.   AMERICAN JOURNAL OF PERINATOLOGY

Pharmacokinetics of Metformin during Pregnancy

(2010) S. Eyal et al.   DRUG METABOLISM AND DISPOSITION

Race, Ethnicity, Ancestry, and Pharmacogenetics

(2010) Thomas J. Urban   MOUNT SINAI JOURNAL OF MEDICINE

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Pharmacogenomics of membrane transporters: past, present and future

(2010) Sook Wah Yee et al.   PHARMACOGENOMICS

Pregnancy Reduces the Accuracy of the Estimated Glomerular Filtration Rate Based on Cockroft-Gault and MDRD Formulas

(2010) Patricia M. J. L. Koetje et al.   Reproductive Sciences

Revised Equations for Estimated GFR From Serum Creatinine in Japan

(2009) Seiichi Matsuo et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Creatinine reabsorption by the aged kidney

(2009) Carlos G. Musso et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Interaction of Organic Cations with Organic Anion Transporters

(2009) Sun-Young Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Human Multidrug and Toxin Extrusion 1 in the Drug Interaction between Cimetidine and Metformin in Renal Epithelial Cells

(2009) M. Tsuda et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Participation of Women in Clinical Trials for New Drugs Approved by the Food and Drug Administration in 2000–2002

(2009) Yongsheng Yang et al.   JOURNAL OF WOMENS HEALTH

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin

(2009) Ying Chen et al.   Pharmacogenetics and Genomics

Optimizing Pediatric Dosing: A Developmental Pharmacologic Approach

(2009) Gail D Anderson et al.   PHARMACOTHERAPY

Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study

(2008) MF Hebert et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effect of Pregnancy on Cytochrome P450 3a and P-Glycoprotein Expression and Activity in the Mouse: Mechanisms, Tissue Specificity, and Time Course

(2008) H. Zhang et al.   MOLECULAR PHARMACOLOGY