Pathogenesis of Plexiform Neurofibroma: Tumor-Stromal/Hematopoietic Interactions in Tumor Progression

Phase I trial of pegylated interferon- -2b in young patients with plexiform neurofibromas

(2011) R. I. Jakacki et al.   NEUROLOGY

Nf1−/− Schwann Cell-Conditioned Medium Modulates Mast Cell Degranulation by c-Kit-Mediated Hyperactivation of Phosphatidylinositol 3-Kinase

(2010) Shi Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular and Cellular Mechanisms of Learning Disabilities: A Focus on NF1

(2010) C. Shilyansky et al.   Annual Review of Neuroscience

Neurofibromatosis type 1 (NF1) and pheochromocytoma: prevalence, clinical and cardiovascular aspects

(2010) Laura Zinnamosca et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Mast cells and the neurofibroma microenvironment

(2010) K. Staser et al.   BLOOD

Cyclic AMP Suppression Is Sufficient to Induce Gliomagenesis in a Mouse Model of Neurofibromatosis-1

(2010) N. M. Warrington et al.   CANCER RESEARCH

Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level

(2010) Christopher B. Franco et al.   Cell Stem Cell

Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells

(2010) Karl Staser et al.   CURRENT OPINION IN HEMATOLOGY

Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner

(2010) D. Y. Lee et al.   GENES & DEVELOPMENT

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

(2010) Elisabeth A. Lasater et al.   JOURNAL OF CLINICAL INVESTIGATION

Neurofibromatosis-1 Heterozygosity Increases Microglia in a Spatially and Temporally Restricted Pattern Relevant to Mouse Optic Glioma Formation and Growth

(2010) Grant W. Simmons et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The ecology of brain tumors: lessons learned from neurofibromatosis-1

(2010) W W Pong et al.   ONCOGENE

Cell of Origin and Microenvironment Contribution for NF1-Associated Dermal Neurofibromas

(2009) Lu Q. Le et al.   Cell Stem Cell

Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation

(2009) Tu-Hsueh Yeh et al.   GLIA

Unravelling the genetic basis of variable clinical expression in neurofibromatosis 1

(2009) Audrey Sabbagh et al.   HUMAN MOLECULAR GENETICS

Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model

(2009) Maria Demestre et al.   JOURNAL OF NEURO-ONCOLOGY

Ras Dependent Paracrine Secretion of Osteopontin by Nf1+/− Osteoblasts Promote Osteoclast Activation in a Neurofibromatosis Type I Murine Model

(2009) Huijie Li et al.   PEDIATRIC RESEARCH

Translation of the Philadelphia chromosome into therapy for CML

(2008) B. J. Druker   BLOOD

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells

(2008) A. S. McDaniel et al.   BLOOD

Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin

(2008) Mateusz Kolanczyk et al.   BMC Medicine

Induction of Abnormal Proliferation by Nonmyelinating Schwann Cells Triggers Neurofibroma Formation

(2008) Huarui Zheng et al.   CANCER CELL

Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells

(2008) Jianqiang Wu et al.   CANCER CELL

The Loss of Nf1 Transiently Promotes Self-Renewal but Not Tumorigenesis by Neural Crest Stem Cells

(2008) Nancy M. Joseph et al.   CANCER CELL

Increased c-Jun-NH2-Kinase Signaling in Neurofibromatosis-1 Heterozygous Microglia Drives Microglia Activation and Promotes Optic Glioma Proliferation

(2008) G. C. Daginakatte et al.   CANCER RESEARCH

Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/−- and c-kit-Dependent Bone Marrow

(2008) Feng-Chun Yang et al.   CELL

Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning

(2008) Yijun Cui et al.   CELL

How does the Schwann cell lineage form tumors in NF1?

(2008) Steven L. Carroll et al.   GLIA

Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway

(2008) E. A. Lasater et al.   HUMAN MOLECULAR GENETICS

New developments in mast cell biology

(2008) Janet Kalesnikoff et al.   NATURE IMMUNOLOGY

Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis

(2007) Stephen J. Galli et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Somatic Mutation Analysis in NF1 Café au lait Spots Reveals Two NF1 Hits in the Melanocytes

(2007) Sofie De Schepper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY