Ecdysone Receptors: From the Ashburner Model to Structural Biology

The Juvenile Hormone Signaling Pathway in Insect Development

(2012) Marek Jindra et al.   Annual Review of Entomology

Molecular adaptation and resilience of the insect’s nuclear receptor USP

(2012) Arnaud Chaumot et al.   BMC EVOLUTIONARY BIOLOGY

Coordination of Triacylglycerol and Cholesterol Homeostasis by DHR96 and the Drosophila LipA Homolog magro

(2011) Matthew H. Sieber et al.   Cell Metabolism

Nitric oxide coordinates metabolism, growth, and development via the nuclear receptor E75

(2011) L. Caceres et al.   GENES & DEVELOPMENT

Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling

(2011) Donya Tohidi-Esfahani et al.   PEST MANAGEMENT SCIENCE

Molecular Evolution of Ultraspiracle Protein (USP/RXR) in Insects

(2011) Ekaterina F. Hult et al.   PLoS One

Synthesis, binding and bioactivity of γ-methylene γ-lactam ecdysone receptor ligands: Advantages of QSAR models for flexible receptors

(2010) Woldeamanuel Birru et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural diversity and evolution of the N-terminal isoform-specific region of ecdysone receptor-A and -B1 isoforms in insects

(2010) Takayuki Watanabe et al.   BMC EVOLUTIONARY BIOLOGY

The genome of the nematode Pristionchus pacificus encodes putative homologs of RXR/Usp and EcR

(2010) Manish Parihar et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

An ecdysone receptor from the pentatomomorphan, Nezara viridula, shows similar affinities for moulting hormones makisterone A and 20-hydroxyecdysone

(2010) Donya Tohidi-Esfahani et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

An ortholog of the ecdysone receptor protein (EcR) from the parasitic nematode Haemonchus contortus

(2010) Lloyd D. Graham et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

An EcR homolog from the filarial parasite, Dirofilaria immitis requires a ligand-activated partner for transactivation

(2010) Cathy Shea et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

What are nuclear receptor ligands?

(2010) Frances M. Sladek   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Origin and evolution of the ligand-binding ability of nuclear receptors

(2010) Gabriel V. Markov et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Intrinsic disorder of Drosophila melanogaster hormone receptor 38 N-terminal domain

(2010) Agnieszka Dziedzic-Letka et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular Evidence for a Functional Ecdysone Signaling System in Brugia malayi

(2010) George Tzertzinis et al.   PLoS Neglected Tropical Diseases

Nuclear ReceptorsHomo sapiensRev-erbβ andDrosophila melanogasterE75 Are Thiolate-Ligated Heme Proteins Which Undergo Redox-Mediated Ligand Switching and Bind CO and NO

(2009) Katherine A. Marvin et al.   BIOCHEMISTRY

Protein structure based rational design of ecdysone agonists

(2009) Graham Holmwood et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ecdysteroid hormone action

(2009) Klaus-Dieter Spindler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Arthropod nuclear receptors and their role in molting

(2009) Yoshiaki Nakagawa et al.   FEBS Journal

Suppression of the ecdysteroid-triggered growth arrest by a novelDrosophilamembrane steroid binding protein

(2009) Ikuko Fujii-Taira et al.   FEBS LETTERS

Structural and Evolutionary Innovation of the Heterodimerization Interface between USP and the Ecdysone Receptor ECR in Insects

(2009) T. Iwema et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

(2009) Keith I Pardee et al.   PLOS BIOLOGY

Annotation of Tribolium nuclear receptors reveals an increase in evolutionary rate of a network controlling the ecdysone cascade

(2008) François Bonneton et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Edysone receptor isoforms play distinct roles in controlling molting and metamorphosis in the red flour beetle, Tribolium castaneum

(2008) Anjiang Tan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

The evolution of the Ecdysozoa

(2008) M. J Telford et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect

(2008) S. M. Nowickyj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoform-specific variation in the intrinsic disorder of the ecdysteroid receptor N-terminal domain

(2008) Małgorzata Nocula-Ługowska et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Caenorhabditis elegans nuclear receptors: insights into life traits

(2008) Daniel B. Magner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Novel Ecdysone Receptor Mediates Steroid-Regulated Developmental Events during the Mid-Third Instar of Drosophila

(2008) Benjamin F. B. Costantino et al.   PLoS Genetics