Cooperation Between Integrins and Growth Factor Receptors in Signaling and Endocytosis

Regulation of Integrin Activation

(2011) Chungho Kim et al.   Annual Review of Cell and Developmental Biology

Angiopoietin-Like 4 Interacts with Integrins β1 and β5 to Modulate Keratinocyte Migration

(2010) Yan Yih Goh et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial α3β1-Integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF

(2010) Rita Graça da Silva et al.   AMERICAN JOURNAL OF PATHOLOGY

Collagen I matrix turnover is regulated by fibronectin polymerization

(2010) Feng Shi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Deciphering the human platelet sheddome

(2010) K. P. Fong et al.   BLOOD

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

(2010) Elina Mattila et al.   BMC CANCER

Tetraspanin CD151 Regulates Transforming Growth Factor   Signaling: Implication in Tumor Metastasis

(2010) R. Sadej et al.   CANCER RESEARCH

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

(2010) Kathrin S. Zeller et al.   CELLULAR SIGNALLING

Segmentation and tracking of cytoskeletal filaments using open active contours

(2010) Matthew B. Smith et al.   Cytoskeleton

Endothelial  5 and  v integrins cooperate in remodeling of the vasculature during development

(2010) A. van der Flier et al.   DEVELOPMENT

Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes

(2010) Viola Hélène Lobert et al.   DEVELOPMENTAL CELL

Integrin-Linked Kinase Controls Microtubule Dynamics Required for Plasma Membrane Targeting of Caveolae

(2010) Sara A. Wickström et al.   DEVELOPMENTAL CELL

Angiopoietin-2 Stimulation of Endothelial Cells Induces αvβ3 Integrin Internalization and Degradation

(2010) Markus Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Binding of the EGF-like Domain of Neuregulin-1 to Integrins (αvβ3 and α6β4) Is Involved in Neuregulin-1/ErbB Signaling

(2010) Katsuaki Ieguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin α1β1 Promotes Caveolin-1 Dephosphorylation by Activating T Cell Protein-tyrosine Phosphatase

(2010) Corina M. Borza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

The α2β1 integrin is a metastasis suppressor in mouse models and human cancer

(2010) Norma E. Ramirez et al.   JOURNAL OF CLINICAL INVESTIGATION

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

Mammary-derived growth inhibitor (MDGI) interacts with integrin α-subunits and suppresses integrin activity and invasion

(2010) J Nevo et al.   ONCOGENE

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Protein Kinase D1 Regulates VEGF-A-Induced αvβ3 Integrin Trafficking and Endothelial Cell Migration

(2010) Laura Di Blasio et al.   TRAFFIC

The Membrane-Associated Protein, Supervillin, Accelerates F-Actin-Dependent Rapid Integrin Recycling and Cell Motility

(2010) Zhiyou Fang et al.   TRAFFIC

Signal co-operation between integrins and other receptor systems

(2009) Charles H. Streuli et al.   BIOCHEMICAL JOURNAL

Integrins during evolution: Evolutionary trees and model organisms

(2009) Mark S. Johnson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Agonizing Integrin Antagonists?

(2009) Sara M. Weis et al.   CANCER CELL

Silencing of TMS1/ASC Promotes Resistance to Anoikis in Breast Epithelial Cells

(2009) M. J. Parsons et al.   CANCER RESEARCH

Integrins and Mutant p53 on the Road to Metastasis

(2009) Galina Selivanova et al.   CELL

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

(2009) Maddalena Adorno et al.   CELL

Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes

(2009) Johanna Ivaska et al.   CELL AND TISSUE RESEARCH

RalA-Exocyst Complex Regulates Integrin-Dependent Membrane Raft Exocytosis and Growth Signaling

(2009) Nagaraj Balasubramanian et al.   CURRENT BIOLOGY

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis

(2009) Eleni Bazigou et al.   DEVELOPMENTAL CELL

Molecular mechanism of α2β1 integrin interaction with human echovirus 1

(2009) Johanna Jokinen et al.   EMBO JOURNAL

Genetic and cell biological analysis of integrin outside-in signaling

(2009) K. R. Legate et al.   GENES & DEVELOPMENT

The Direct Binding of Insulin-like Growth Factor-1 (IGF-1) to Integrin αvβ3 Is Involved in IGF-1 Signaling

(2009) Jun Saegusa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

(2009) Anjali Teckchandani et al.   JOURNAL OF CELL BIOLOGY

Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells

(2009) Ellen J. Ezratty et al.   JOURNAL OF CELL BIOLOGY

Mice that lack activity of  v 6- and  v 8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

(2009) P. Aluwihare et al.   JOURNAL OF CELL SCIENCE

Integrins in immunity

(2009) R. Evans et al.   JOURNAL OF CELL SCIENCE

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

Integrin signal masks growth-promotion activity of HB-EGF in monolayer cell cultures

(2009) H. Mizushima et al.   JOURNAL OF CELL SCIENCE

Activation of Protein Kinase C α Is Necessary for Sorting the PDGF β-Receptor to Rab4a-dependent Recycling

(2009) Carina Hellberg et al.   MOLECULAR BIOLOGY OF THE CELL

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

Regulation of endocytosis via the oxygen-sensing pathway

(2009) Yi Wang et al.   NATURE MEDICINE

Integrins: masters and slaves of endocytic transport

(2009) Patrick T. Caswell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of cell signalling by uPAR

(2009) Harvey W. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Absence of αvβ6 Integrin Is Linked to Initiation and Progression of Periodontal Disease

(2008) Farzin Ghannad et al.   AMERICAN JOURNAL OF PATHOLOGY

Anoikis resistance and tumor metastasis

(2008) Craig D. Simpson et al.   CANCER LETTERS

Hypoxia-Inducible Factor 1  Mediates Anoikis Resistance via Suppression of  5 Integrin

(2008) N. Rohwer et al.   CANCER RESEARCH

Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion

(2008) B. Joshi et al.   CANCER RESEARCH

Cell adhesion receptors in mechanotransduction

(2008) Martin A Schwartz et al.   CURRENT OPINION IN CELL BIOLOGY

Integrin Trafficking Regulated by Rab21 Is Necessary for Cytokinesis

(2008) Teijo Pellinen et al.   DEVELOPMENTAL CELL

Polymerized Collagen Inhibits Fibroblast Proliferation via a Mechanism Involving the Formation of a β1 Integrin-Protein Phosphatase 2A-Tuberous Sclerosis Complex 2 Complex That Suppresses S6K1 Activity

(2008) Hong Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling

(2008) Seiji Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

(2008) Jacky G. Goetz et al.   JOURNAL OF CELL BIOLOGY

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments

(2008) Patrick T. Caswell et al.   JOURNAL OF CELL BIOLOGY

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling

(2008) E. Mattila et al.   JOURNAL OF CELL SCIENCE

Integrin α9β1 is a receptor for nerve growth factor and other neurotrophins

(2008) Izabela Staniszewska et al.   JOURNAL OF CELL SCIENCE

Caveolin-1-dependent  1 integrin endocytosis is a critical regulator of fibronectin turnover

(2008) F. Shi et al.   JOURNAL OF CELL SCIENCE

A Raft-derived, Pak1-regulated Entry Participates in α2β1 Integrin-dependent Sorting to Caveosomes

(2008) Mikko Karjalainen et al.   MOLECULAR BIOLOGY OF THE CELL

Endocytic transport of integrins during cell migration and invasion

(2008) Patrick Caswell et al.   TRENDS IN CELL BIOLOGY

Semaphorin 7a Promotes Spreading and Dendricity in Human Melanocytes through β1-Integrins

(2007) Glynis A. Scott et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY