Large-Scale Structural Biology of the Human Proteome

Lessons from Structural Genomics

(2009) Thomas C. Terwilliger et al.   Annual Review of Biophysics

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

(2009) Alastair J. Barr et al.   CELL

Histone modifying enzymes: Structures, mechanisms, and specificities

(2008) Ronen Marmorstein et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)

(2008) Ashok V. Purandare et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The unfoldomics decade: an update on intrinsically disordered proteins

(2008) A Keith Dunker et al.   BMC GENOMICS

The tyrosine phosphatase Shp2 (PTPN11) in cancer

(2008) Gordon Chan et al.   CANCER AND METASTASIS REVIEWS

Structural Coupling of SH2-Kinase Domains Links Fes and Abl Substrate Recognition and Kinase Activation

(2008) Panagis Filippakopoulos et al.   CELL

Similar Biological Activities of Two Isostructural Ruthenium and Osmium Complexes

(2008) Jasna Maksimoska et al.   CHEMISTRY-A EUROPEAN JOURNAL

Doing more than just the structure—structural genomics in kinase drug discovery

(2008) Brian D Marsden et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The emerging functions of histone demethylases

(2008) Karl Agger et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites

(2008) Ashley C W Pike et al.   EMBO JOURNAL

Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery

(2008) Paul Bamborough et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acetylation of EKLF Is Essential for Epigenetic Modification and Transcriptional Activation of the  -Globin Locus

(2008) T. Sengupta et al.   MOLECULAR AND CELLULAR BIOLOGY

What histone code for DNA repair?

(2008) Alexandre E. Escargueil et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Structural genomics: from genes to structures with valuable materials and many questions in between

(2008) Brian G Fox et al.   NATURE METHODS

Protein crystallization: from purified protein to diffraction-quality crystal

(2008) Naomi E Chayen et al.   NATURE METHODS

Large-scale evaluation of protein reductive methylation for improving protein crystallization

(2008) Youngchang Kim et al.   NATURE METHODS

Protein production and purification

(2008) Susanne Gräslund et al.   NATURE METHODS

DNA methylation landscapes: provocative insights from epigenomics

(2008) Miho M. Suzuki et al.   NATURE REVIEWS GENETICS

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein  -subunits

(2008) M. Soundararajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic Reprogramming by Adenovirus e1a

(2008) R. Ferrari et al.   SCIENCE

PSI Has to Live and Become PCI: Protein Complex Initiative

(2008) Ilya A. Vakser   STRUCTURE