Review
Cardiac & Cardiovascular Systems
Anuradha Kalyanasundaram, Ning Li, Ralph S. Augostini, Raul Weiss, John D. Hummel, Vadim V. Fedorov
Summary: This article introduces the anatomy, activation mechanism, and arrhythmias related to the sinoatrial node (SAN). The complex structure and conduction mechanism of the SAN pose challenges in clinical mapping and ablation procedures, and incorrect diagnosis and treatment may lead to poor outcomes. The aim of the article is to provide a state-of-the-art overview of the 3D structure, function, and treatment approaches of SAN and atrial arrhythmias to improve diagnosis and mechanistic treatment.
Review
Cardiac & Cardiovascular Systems
Reza Hosseini Dolama, Amir Hosein Eghbal, Malihe Rezaee, Ali Vasheghani Farahani, Arash Jalali, Kaveh Hosseini
Summary: This study systematically reviewed the evidence on the prevalence of sinus node dysfunction (SND), permanent pacemaker (PPM) implantation, and their management approaches following cardiac surgeries. The results showed that patients undergoing maze and maze-valve procedures are at higher risk of post-op SND, while lone valve surgery had the lowest prevalence of PPM implantation. Rating: 8/10
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Lei Wang, Zhijun Liu, Zhongliang He, Chun Zhang
Summary: This article reports a case of a 67-year-old female patient with a history of breast cancer surgery and multiple cycles of radiotherapy and chemotherapy, who developed chest wall sinus with infection. The patient underwent two-stage surgery and was successfully cured. Clinical evidence shows that the use of a pedicled latissimus dorsi myocutaneous flap is an effective method for treating intractable chest wall sinus.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Muhammad Umer Butt, Nazli Okumus, Ahmad Jabri, Charles Thomas, Yasir Tarabichi, Saima Karim
Summary: This study analyzed the relationship between the timing of catheter ablation for atrial fibrillation (AF) and the need for permanent pacemaker (PPM) implantation in patients with sick sinus syndrome. The results showed that patients who underwent catheter ablation within 5 years of sick sinus syndrome diagnosis had the lowest rate of PPM implantation.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Medicine, General & Internal
Tsuyoshi Ota, Katsunori Okajima, Yuichi Nagamatsu, Tomoyuki Nakanishi, Yasuhiro Kaetsu, Takahiro Sawada, Takeaki Shirai, Rio Shiraki, Makoto Kadotani, Yoshio Onishi
Summary: In this case report, a 46-year-old woman with COVID-19 infection developed symptomatic sinus bradycardia and congestive heart failure. Despite the administration of various therapies, including isoproterenol, theophylline, and cilostazol, her symptoms did not improve. She eventually underwent pacemaker implantation 53 days after admission, with 60% atrial pacing remaining after 6 months.
CLINICAL CASE REPORTS
(2023)
Review
Cardiac & Cardiovascular Systems
Vasiliki Patsiou, Anna-Bettina Haidich, Amalia Baroutidou, Andreas Giannopoulos, George Giannakoulas
Summary: This systematic review and meta-analysis compared the use of epicardial and endocardial pacemakers in children with atrioventricular block or sinus node dysfunction. The results showed that epicardial pacemakers were more likely to lead to lead failure compared to endocardial pacemakers, but there were no significant differences in threshold rise, post-implantation infection, battery depletion, and mortality rates.
PEDIATRIC CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Alexander Sharp, Gareth Matthews, Nikolaos Papageorgiou, Richard Till, Daniel Raine, Ian Williams, Cairistine Grahame-Clarke, Santosh Nair, Omar Abdul-Samad, Vassilios Vassiliou, Pankaj Garg, Wei Yao Lim
Summary: The study found that patients who underwent pacemaker implantation for symptomatic sinus node dysfunction had significantly lower mortality rates when the procedure was performed in an outpatient setting rather than during an inpatient admission.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmed Habbout, Audrey Sagnard, Thibaut Pommier, Romain Didier, Fabien Garnier, Marie Fichot, Geraldine Bertaux, Gabriel Laurent, Charles Guenancia
Summary: This retrospective study analyzed patients with reversible high-degree symptomatic sinus node dysfunction (SND) and atrioventricular block (AVB), excluding acute myocardial infarction and post-cardiac surgery patients. The results showed that nearly one third of the patients required pacemaker implantation at follow-up. Patients with complete bundle branch block or left bundle branch hemiblock on discharge ECG were more likely to experience recurrence leading to pacemaker implantation.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Amy L. Rahm, Jacob A. Razzouk, Carter S. Foster, Sonia L. Voleti, Anees J. Razzouk, Randall S. Fortuna
Summary: Through a retrospective study of 38 patients with a follow-up of at least five years after external pericardial lateral tunnel Fontan (EPLTF) surgery, it was found that the EPLTF pathway enlarges over time in correlation with increasing body surface area (BSA). Significant enlargement was observed at three distinct locations along the pathway. Further research is needed to determine the ideal pathway size, differentiate normal physiologic growth from pathologic enlargement, and correlate changes with clinical outcomes.
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Ioannis Doundoulakis, Konstantinos A. Gatzoulis, Petros Arsenos, Polychronis Dilaveris, Ioannis Skiadas, Dimitrios Tsiachris, Christos-Konstantinos Antoniou, Stergios Soulaidopoulos, George Karystinos, Voula Pylarinou, Maria Drakopoulou, Skevos Sideris, Charalambos Vlachopoulos, Dimitrios Tousoulis
Summary: The study aimed to evaluate the effect of permanent pacing on the incidence of syncope in patients with mild degree of SB, and found that among patients with positive invasive electrophysiology testing, receiving ABP significantly reduced the rate of syncope.
JOURNAL OF ARRHYTHMIA
(2021)
Article
Cardiac & Cardiovascular Systems
Tomofumi Mizuno, Nobuhiro Nishii, Hiroshi Morita, Hiroshi Ito
Summary: This report describes a case of successful management of atrial tachycardia and sinus node dysfunction in an elderly Fontan patient through transvenous pacemaker implantation via the right femoral vein. This is a feasible option when open thoracic surgery or catheter ablation is not possible.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Carlo de Asmundis, Luigi Pannone, Dhanunjaya Lakkireddy, Thomas M. Beaver, Chad R. Brodt, Randall J. Lee, Kenneth Frazier, Gian-Battista Chierchia, Mark La Meir
Summary: The goal of the HEAL-IST trial is to evaluate the safety and effectiveness of hybrid sinus node-sparing ablation therapy for symptomatic IST patients who are refractory or intolerant to drugs. This prospective, multicenter trial will treat up to 142 subjects with a Bayesian adaptive design. The primary safety endpoint is assessed through 30 days post-procedure, while the primary effectiveness endpoint measures freedom from IST at 12 months.
Article
Cardiac & Cardiovascular Systems
Karthik Gonuguntla, Komal Ejaz, Chaitanya Rojulpote, Ayesha Shaik, Abhijit Bhattaru, Tapan Buch, Sreekant Avula, Rahul Rauniyar, Vijay Singh, Pranav Karambelkar, Pranathi Narayanareddy, Kashyap Kela, Richard G. Cowden, Nikola Perosevic, Pranjal Boruah
Summary: This study examined the prevalence of sinus node dysfunction (SND) in patients with systemic lupus erythematosus (SLE) using data from the years 2010 to 2014. The prevalence of SND in patients with SLE was found to be 4.3%, with a 3.6% prevalence of pacemaker (PM) implantation in patients with both SLE and SND over a five-year period. The majority of these patients had a dual-chamber PM (85.6%), and there was an increase in prevalence rates of SND in female patients with SLE over the five-year period. Various complications associated with PM implantation in patients with SLE and SND were also reported.
AMERICAN JOURNAL OF CARDIOVASCULAR DISEASE
(2021)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)
