Review
Medicine, General & Internal
Chayakrit Krittanawong, Johao Escobar, Hafeez Ul Hassan Virk, Mahboob Alam, Nedaa Skeik, Umberto Campia, Peter K. Henke, Samin Sharma
Summary: Lower extremity peripheral artery and upper extremity artery disease are significant vascular conditions that require timely diagnosis and treatment. Lower extremity peripheral artery is associated with worse cardiovascular events, but is often overlooked. Upper extremity artery disease can have multiple causes, not just atherosclerosis. Increased awareness and early intervention can reduce complications and improve patient outcomes.
AMERICAN JOURNAL OF MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sang-Eun Lee, Ji Min Sung, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Eun Ju Chun, Edoardo Conte, Ilan Gottlieb, Martin Hadamitzky, Yong Jin Kim, Byoung Kwon Lee, Jonathon A. Leipsic, Erica Maffei, Hugo Marques, Pedro de Araujo Goncalves, Gianluca Pontone, Sanghoon Shin, Peter H. Stone, Habib Samady, Renu Virmani, Jagat Narula, Daniel S. Berman, Leslee J. Shaw, Jeroen J. Bax, Fay Y. Lin, James K. Min, Hyuk-Jae Chang
Summary: The progression of aortic valve calcification is associated with the progression of calcified plaque volume in coronary atherosclerosis, indicating a potential link between the two conditions.
Article
Cardiac & Cardiovascular Systems
Giancarlo Pirozzolo, Andreas Seitz, Valeria Martinez Pereyra, Anastasios Athanasiadis, Marc Albert, Ulrich F. W. Franke, Raffi Bekeredjian, Udo Sechtem, Peter Ong
Summary: Epicardial and microvascular coronary artery spasm are common findings in patients with ongoing or recurrent angina after CABG but no relevant stenosis. Vasoreactivity to acetylcholine differs significantly between LITA bypasses and native LAD arteries, with vasoconstriction primarily occurring in the LAD.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Per Morten Molstad, Jan Erik Nordrehaug, Terje K. Steigen, Tom Wilsgaard, Rune Wiseth, Svein Rotevatn, Jan Mannsverk, Tommy Larsen, Kristina Elisabet Larsby, Sigrun Adnegard Skarstad, Eivind Oygard Fosse, Oystein Dahl-Eriksen, Kaare Harald Bonaa
Summary: This study compared drug-eluting stents (DES) with bare-metal stents (BMS) in terms of target lesion revascularization (TLR) rate in native vessels and saphenous vein grafts (SVG). The results showed that DES had a persistent benefit in reducing TLR rate in native vessels after 5 years, but there was no difference between DES and BMS in SVG. The high rate of TLR and myocardial infarction (MI) in SVG suggests that treating native vessels should be preferred whenever possible.
Article
Cardiac & Cardiovascular Systems
Daniel J. F. M. Thuijs, Piroze Davierwala, Milan Milojevic, Salil Deo, Thilo Noack, A. Pieter Kappetein, Patrick W. Serruys, Friedrich-Wilhelm Mohr, Marie-Claude Morice, Michael J. Mack, L. Elisabeth G. E. Stahle, Niels J. Verberkmoes, David R. Holmes, Stuart J. Head
Summary: The study found that patients who underwent multiple arterial grafts (MAG) in the SYNTAX study had a significantly lower all-cause death rate at the 12.6-year follow-up compared to those who received single arterial grafts (SAG).
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Natasa Javorszky, Balint Homonnay, Gary Gerstenblith, David Bluemke, Peter Kiss, Mihaly Torok, David Celentano, Hong Lai, Shenghan Lai, Marton Kolossvary
Summary: This study developed an open-source deep learning model for segmenting coronary plaques on coronary CT angiography. The model showed excellent performance in quantifying plaque volumes in both the test set and an external dataset, and transfer learning further improved the accuracy of the model.
EUROPEAN RADIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Alexander R. van Rosendael, Inge J. van den Hoogen, Umberto Gianni, Xiaoyue Ma, Sara W. Tantawy, A. Maxim Bax, Yao Lu, Daniele Andreini, Mouaz H. Al-Mallah, Matthew J. Budoff, Filippo Cademartiri, Kavitha Chinnaiyan, Jung Hyun Choi, Edoardo Conte, Hugo Marques, Pedro de Araujo Goncalves, Ilan Gottlieb, Martin Hadamitzky, Jonathon A. Leipsic, Erica Maffei, Gianluca Pontone, Sanghoon Shin, Yong-Jin Kim, Byoung Kwon Lee, Eun Ju Chun, Ji Min Sung, Sang-Eun Lee, Renu Virmani, Habib Samady, Yu Sato, Peter H. Stone, Daniel S. Berman, Jagat Narula, Ron Blankstein, James K. Min, Fay Y. Lin, Leslee J. Shaw, Jeroen J. Bax, Hyuk-Jae Chang
Summary: The study found that statin therapy is associated with increased transformation of coronary atherosclerosis towards high-density calcium, supporting the concept of reduced atherosclerotic risk with increased densification of calcium.
Article
Cardiac & Cardiovascular Systems
Alex L. Huang, Jonathon A. Leipsic, Sagit Ben Zekry, Stephanie Sellers, Amir A. Ahmadi, Philipp Blanke, Martin Hadamitzky, Yong-Jin Kim, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Matthew J. Budoff, Ilan Gottlieb, Byoung Kwon Lee, Eun Ju Chun, Filippo Cademartiri, Erica Maffei, Hugo Marques, Sanghoon Shin, Jung Hyun Choi, Renu Virmani, Habib Samady, Peter H. Stone, Daniel S. Berman, Jagat Narula, Leslee J. Shaw, Jeroen J. Bax, Hyuk-Jae Chang
Summary: The study found that the change in atherosclerotic plaque volume in patients with chronic kidney disease is associated with declining renal function, but does not directly lead to plaque progression. Instead, the decline in renal function is more closely related to plaque progression.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Review
Cardiac & Cardiovascular Systems
Luke P. Dawson, Mark Lum, Nitesh Nerleker, Stephen J. Nicholls, Jamie Layland
Summary: Advancements in treatments aimed at reducing cardiovascular events have been paralleled by improvements in coronary imaging modalities to assess plaque volumes and composition. Studies aiming to demonstrate plaque regression and improvements in high-risk features have potential to reduce cardiovascular events in the future.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Yan-Feng Zhou, Yanxiu Wang, Guodong Wang, Zhen Zhou, Shuohua Chen, Tingting Geng, Yan-Bo Zhang, Yi Wang, Jun-Xiang Chen, An Pan, Shouling Wu
Summary: This study aimed to investigate the association between statin use and progression of arterial stiffness in Chinese adults with high atherosclerotic risk. The results showed that statin use was associated with lower baseline baPWV and slower progression of baPWV.
Article
Cardiac & Cardiovascular Systems
Rui Lv, Liang Wang, Akiko Maehara, Xiaoya Guo, Jie Zheng, Habib Samady, Don P. Giddens, Gary S. Mintz, Gregg W. Stone, Dalin Tang
Summary: This article reviews the application of image-based computational modeling in quantifying plaque morphology and biomechanical conditions for understanding plaque evolution and rupture process. The progress made in plaque progression and vulnerability prediction studies is discussed. However, inconsistencies and differences in existing literature make direct comparison and analysis challenging.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Changjing Feng, Rui Chen, Siting Dong, Wei Deng, Shushen Lin, Xiaomei Zhu, Wangyan Liu, Yi Xu, Xiaohu Li, Yinsu Zhu
Summary: By analyzing clinical data and CCTA images of 400 patients, it was found that FAI and NCPB were independent risk factors for coronary plaque progression. Combining conventional parameters with radiomics features derived from CCTA can better predict plaque progression.
EUROPEAN RADIOLOGY
(2023)
Article
Physiology
Haipeng Liu, Aleksandra Wingert, Xinhong Wang, Jucheng Zhang, Jianzhong Sun, Fei Chen, Syed Ghufran Khalid, Yinglan Gong, Ling Xia, Jun Jiang, Jian'an Wang, Dingchang Zheng
Summary: In this study, the geometric properties of coronary plaques of different sizes were investigated, revealing a positive relationship between the number and volume of coronary plaques and calcifications in patients with coronary artery disease. The findings suggest consistency in the relationship between geometric parameters of different dimensions in various coronary plaques.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Zixiang Ye, Yaxin Wu, Yimin Tu, Mulei Chen, Yanxiang Gao, Linying Shi, Peizhao Li, Enmin Xie, Ziyu Guo, Qing Li, Xiaozhai Yu, Yike Li, Wenquan Niu, Jingyi Ren, Jingang Zheng
Summary: This study demonstrates that blood group O may be negatively associated with the risk and severity of coronary artery disease (CAD) in end-stage renal disease (ESRD) patients undergoing dialysis, while blood groups A, B, and AB may be positively associated with the severity of CAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Daniel Bos, Banafsheh Arshi, Quirijn J. A. van den Bouwhuijsen, M. Kamran Ikram, Mariana Selwaness, Meike W. Vernooij, Maryam Kavousi, Aad van der Lugt
Summary: This study found that hemorrhage in carotid atherosclerotic plaque is an independent risk factor for stroke and coronary heart disease.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)