Article
Cardiac & Cardiovascular Systems
Domenico Spinelli, Fred A. Weaver, Ali Azizzadeh, Gregory A. Magee, Gabriele Piffaretti, Filippo Benedetto, Charles C. Miller, Harleen K. Sandhu, Dennis R. Gable, Santi Trimarchi
Summary: The study aimed to analyze the outcomes of thoracic endovascular aortic repair for complicated and uncomplicated acute type B aortic dissections. The data from WL Gore's Global Registry for Endovascular Aortic Treatment showed that the 30-day mortality and perioperative complications were equally low for both complicated and uncomplicated type B aortic dissections, and the midterm outcome was positive.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Surgery
Takuya Ogami, George J. Arnaoutakis, Himanshu J. Patel, Chih-Wen Pai, Kim A. Eagle, Santi Trimarchi, Derek Serna-Gallegos, Ibrahim Sultan
Summary: This study aimed to characterize acute kidney injury (AKI) after thoracic endovascular aortic repair (TEVAR) in patients with acute type B aortic dissection (ATBAD). The incidence of postoperative AKI was found to be 16.2% in patients undergoing TEVAR for ATBAD. Patients with postoperative AKI had a higher rate of in-hospital morbidities and mortality than those without AKI. A history of chronic kidney disease (CKD) and preoperative AKI were independently associated with postoperative AKI.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Ruihan Wang, Yuanqing Kan, Mou Yang, Hongkun Zhang, Xiaoming Zhang, Xiangchen Dai, Shuiting Zhai, Hejie Hu, Xiwei Zhang, Bing Chen, Jianhua Huang, Xiao Qin, Zhanxiang Xiao, Xinwu Lu, Wei Guo, Yi Si, Weiguo Fu
Summary: This study aimed to report the clinical outcomes and aortic remodeling after the implantation of the Fabulous thoracic stent system. The results showed favorable clinical benefits of the Fabulous system, with low short-term mortality and a low incidence of reintervention. Patients also exhibited remodeling in both the descending aorta and distal aorta, with varying volumetric changes in different segments.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Guangmin Yang, Hongwei Ge, Guangyan Wu, Yepeng Zhang, Leiyang Zhang, Ming Zhang, Xiaoqiang Li, Min Zhou
Summary: This study compared the effects of thoracic endovascular aortic repair (TEVAR) on patients with acute, subacute, and chronic type B aortic dissection (TBAD). The results showed that patients with acute and subacute TBAD had fewer complications and better aortic remodeling after TEVAR.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Surgery
Jeniann A. Yi, Ryan Gupta, Quy Tat, Helen A. Potter, Sukgu M. Han, Fernando Fleischman, Donald Jacobs, Mark Nehler, Gregory A. Magee
Summary: In this study, medical management of acute uncomplicated TBAD was associated with higher rates of readmission and the need for unplanned operation compared with TEVAR. However, no differences were found in the 1-year mortality for the patients for whom medical management had failed. This finding suggests clinical equipoise for the treatment of acute uncomplicated TBAD and supports the need for a larger randomized trial to determine whether early TEVAR provides clear benefits.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Xiao-Fu Dai, Guan-Hua Fang, Liang-Liang Yan, Yi Dong, Gui-Can Zhang, Zheng Xu, Liang-Wan Chen
Summary: The study evaluated the midterm outcomes of 147 patients who underwent valve-sparing aortic root repair with the patch neointima technique for acute type A aortic dissection. The results demonstrated stable function of aortic valves and no expansion of the aortic root in the midterm follow-up period.
ANNALS OF THORACIC SURGERY
(2021)
Article
Surgery
Joseph Lombardi, Thomas G. Gleason, Jean M. Panneton, Benjamin W. Starnes, Michael D. Dake, Stephan Haulon, Peter J. Mossop, Edem Segbefia, Priya Bharadwaj
Summary: The 5-year outcomes of using the Zenith Dissection Endovascular System for the treatment of acute, complicated type B aortic dissection show a low rate of dissection-related mortality and a positive effect on false lumen thrombosis. Continuous monitoring for distal aortic growth is necessary for all patients.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Christopher Lau, Giovanni Soletti, Kendall M. Lawrence, Mohamed Rahouma, Erin Iannacone, Ivancarmine Gambardella, Mario Gaudino, Leonard N. Girardi
Summary: This study compares the outcomes of open repair for acute complicated type B aortic dissection (ACTBAD) with standard repair. The results show that in an experienced center, open repair of ACTBAD can be performed with low rates of operative mortality and morbidity, achieving outcomes similar to elective repair even in high-risk patients.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Joseph E. Bavaria, William T. Brinkman, G. Chad Hughes, Aamir S. Shah, Kristofer M. Charlton-Ouw, Ali Azizzadeh, Rodney A. White
Summary: Thoracic endovascular aortic repair showed positive and sustained aortic remodeling in the treatment of acute complicated type B aortic dissections. After 5 years, patients had stable or increased true lumen diameters and reduced false lumen diameters. Compliance for clinical follow-up was 78%.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Surgery
Matthew C. Chia, Rhami Khorfan, Mark K. Eskandari
Summary: A study found that about one third of patients undergoing TEVAR for acute TBAD with malperfusion required adjunctive arterial branch interventions, but this did not lead to worse overall outcomes for the patients.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Dan Yi, Xiatian Liu, Libin Fan
Summary: This article presents a rare case of pheochromocytoma combined with aortic dissection. The presence of pheochromocytoma complicates the surgical treatment of aortic dissection. The detection of elevated 24-hour urinary vanillylmandelic acid levels can aid in the diagnosis of pheochromocytoma. Laparoscopic resection of the adrenal mass can be performed after stabilization and control of hypertension.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Letter
Cardiac & Cardiovascular Systems
Stefano D'Alessandro, Francesco Formica
Summary: This study examined the expression, distribution, and contribution of the KCa channel family in ITA and SV, revealing the significant role of BKCa in vasodilatation of ITA. Differences were found in the abundance and distribution of KCa channel subtypes in the endothelium and smooth muscle between ITA and SV.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Review
Medicine, General & Internal
Fionnuala Jordan, Brian FitzGibbon, Edel P. Kavanagh, Peter McHugh, Dave Veerasingam, Sherif Sultan, Niamh Hynes
Summary: This study aimed to compare the effectiveness and safety of thoracic aortic endovascular repair versus open surgical repair for the treatment of complicated chronic Type B aortic dissection, but no trials meeting the inclusion criteria were identified. Therefore, there is currently no evidence to inform decision-making on the optimal intervention for these patients.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Surgery
Juliet Blakeslee-Carter, Hellen A. Potter, Charles A. Banks, Marc Passman, Benjamin Pearce, Graeme McFarland, Sukgu M. Han, Salvatore Scali, Gregory A. Magee, Emily Spangler, Adam W. Beck
Summary: This study investigated the behavior of the visceral aorta after TEVAR for acute and subacute TBAD and identified predictable TAD growth and the occurrence of VSI. Preoperative anatomical features may play a more significant role in VSI occurrence.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Surgery
Amanda C. Filiberto, Eric Y. Pruitt, Sara E. Hensley, M. Libby Weaver, Samir Shah, Salvatore T. Scali, Dan Neal, Thomas S. Huber, Gilbert R. Upchurch, Michol Cooper
Summary: This study aimed to evaluate the sex-based differences in clinical presentation, time to repair, morbidity, and mortality for patients undergoing thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection (TBAD). The results showed that female patients had a longer overall time from initial symptom onset to TEVAR, but this was not associated with sex-based differences in early or late morbidity or mortality.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Tim Berger, Andreas Voetsch, Diaa Alaloh, Maximilian Kreibich, Philipp Krombholz-Reindl, Andreas Winkler, Bartosz Rylski, Thomas Wolfgruber, Friedhelm Beyersdorf, Matthias Siepe, Rainald Seitelberger, Martin Czerny, Roman Gottardi
Summary: In patients with traumatic aortic injury (TAI), the diameter of the aorta is significantly reduced at discharge compared to admission. The reduction in aortic diameter may be attributed to substantial blood loss.
THORACIC AND CARDIOVASCULAR SURGEON
(2022)
Article
Cardiac & Cardiovascular Systems
Stoyan Kondov, Friedhelm Beyersdorf, Nora Braun, Rene Hoehn, Christopher Schlett, Bartosz Rylski, Matthias Siepe, Maximilian Kreibich, Roman Gottardi, Martin Czerny
Summary: This study evaluated the morphology of the aortic arch, with a focus on the left subclavian artery (LSA). Through a morphological analysis of computed tomography angiography scans of 322 patients, three types of aortic arch morphology were identified. The majority of patients had a type III arch. There were significant differences in the distance between the left common carotid artery (LCCA) and LSA offspring, as well as in the diameter of the LSA, based on the morphological types.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Oncology
Adelina Plangger, Barbara Rath, Maximilian Hochmair, Martin Funovics, Christoph Neumayer, Robert Zeillinger, Gerhard Hamilton
Summary: The study found that fascaplysin exhibits high cytotoxicity against NSCLC cells with a different activity pattern compared to the standard drug cisplatin. Additionally, the combination of fascaplysin and the EGFR tyrosine kinase inhibitor afatinib could enhance the antitumor effect.
INVESTIGATIONAL NEW DRUGS
(2022)
Article
Cardiac & Cardiovascular Systems
Sven R. Hauck, Wolf Eilenberg, Alexander Kupferthaler, Maximilian Kern, Theresa-Marie Dachs, Alexander Wressnegger, Christoph Neumayer, Christian Loewe, Martin A. Funovics
Summary: Using a commercially available steerable sheath allowed successful cannulation of all branches, leading to significantly shorter branch cannulation times. This technique has the potential to lower the risks of stroke and brachial puncture site complications, as well as reduce total intervention time and radiation dose.
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2022)
Article
Surgery
Tomasz Dziodzio, Karl Herbert Hillebrandt, Sebastian Knitter, Maximilian Noesser, Brigitta Globke, Paul Viktor Ritschl, Matthias Biebl, Christian Denecke, Jonas Raakow, Georg Lurje, Wenzel Schoening, Moritz Schmelzle, Andreas Kahl, Markus Futterer, Klemens Budde, Kai-Uwe Eckardt, Fabian Halleck, Johann Pratschke, Robert Oellinger
Summary: Obesity is a significant issue affecting kidney transplantation, but the effectiveness of bariatric surgery for candidates on the waiting list is unclear. Some German centers consider bariatric surgery as an appropriate weight loss therapy, but concerns exist.
Article
Surgery
Marco Nicolas Andreas, Tomasz Dziodzio, Karl-Herbert Hillebrandt, Aron Elsner, Julia Strauchmann, Mustafa Aydin, Johann Pratschke, Jens-Carsten Rueckert, Jens Neudecker
Summary: There are variations in the implementation of ERAS guidelines across different centers in Germany. While some perioperative processes are adequately covered, the full establishment of key features of ERAS in clinical practice is yet to be achieved.
ZENTRALBLATT FUR CHIRURGIE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Christian Loewe
Article
Surgery
Alexander Kupferthaler, Sven R. Hauck, Michael Schwarz, Maximilian Kern, Julia Deinsberger, Theresa-Marie Dachs, Christoph Neumayer, Maria-Elisabeth Stelzmueller, Marek Ehrlich, Christian Loewe, Martin A. Funovics
Summary: This study reports the long-term outcomes of tubular and scalloped TEVAR in treating PAUs and compares the safety profile in both cohorts. The results show that TEVAR and scTEVAR provide excellent and similar clinical success and aortic survival with acceptable complication and reintervention rates. The clinical impact is that more patients can be treated with endovascular repair by including scTEVAR.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Surgery
Anna Sotir, Johannes Klopf, Florian Wolf, Martin A. Funovics, Christian Loewe, Christoph Domenig, Tilo Koelbel, Christoph Neumayer, Wolf Eilenberg
Summary: This retrospective study evaluated the clinical outcomes of F/B-EVAR procedures performed under biplane angiography guidance. The study found that using biplane angiography significantly reduced operation time. There were no significant differences between the two groups in fluoroscopy time, contrast agent volume, and radiation dose.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Oncology
Siyer Roohani, Noa Marie Classen, Felix Ehret, Armin Jarosch, Tomasz Dziodzio, Anne Floercken, Sven Maerdian, Daniel Zips, David Kaul
Summary: This study investigated the role of radiotherapy in addition to surgery for oncological outcomes in patients with malignant peripheral nerve sheath tumors. The results showed that adding radiotherapy to wide surgical excision had a beneficial effect on local control. Patients presenting with local disease recurrence at diagnosis had a significantly negative impact on local control.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Franz Duca, Rene Rettl, Christina Kronberger, Christina Binder, Christopher Mann, Fabian Dusik, Lore Schrutka, Daniel Dalos, Beguem Oeztuerk, Theresa Marie Dachs, Bernhard Cherouny, Luciana Camuz Ligios, Hermine Agis, Renate Kain, Matthias Koschutnik, Carolina Dona, Roza Badr-Eslam, Johannes Kastner, Dietrich Beitzke, Christian Loewe, Christian Nitsche, Christian Hengstenberg, Andreas Anselm Kammerlander, Diana Bonderman
Summary: This study investigated the progression of extracellular volume (ECV) and its prognostic impact in cardiac amyloidosis (CA) patients. The study found that ECV significantly increased over time in all patients, with untreated patients showing a greater change. The change in ECV was a predictor of outcome and could provide important information in evaluating amyloid-specific treatments.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Maximilian Kern, Sven R. Hauck, Theresa-Marie Dachs, Lukas Haider, Marie-Elisabeth Stelzmueller, Marek Ehrlich, Christian Loewe, Martin A. Funovics
Summary: This study evaluated the anatomical suitability of currently manufactured stent grafts and valve-carrying devices for the treatment of type A aortic dissection. The results showed that the anatomical feasibility of commercial stent grafts ranged from 4% to 21%, mainly limited by the proximal landing zone diameter, length, and proximity to the sinotubular junction. The anatomical feasibility of valve-carrying conduits ranged from 31% to 80%, with the main limiting factors being the aortic annulus diameter and its distance to the coronary arteries.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Meeting Abstract
Medicine, General & Internal
T. Aschacher, O. Aschacher, K. Schmidt, F. Enzmann, E. Eichmair, B. Winkler, A. Zsuzsanna, F. Nagel, B. Podesser, A. Mitterbauer, B. Messner, M. Grabenwoeger, G. Laufer, M. Ehrlich, M. Bergmann
WIENER KLINISCHE WOCHENSCHRIFT
(2022)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kevin M. Harris, Kristen M. Westenfield, Neil Parikh, Thomas G. Gleason, Marc Schermerhorn, Maral Ouzounian, Arturo Evangelista, Joseph S. Coselli, Chih-Wen Pai, Marek Ehrlich, Clayton Allen Kaiser, Valerio Tolva, Marco Di Eusanio, Ibrahim Sultan, Kim A. Eagle, Himanshu J. Patel
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Surgery
Robin Ristl, Johannes Klopf, Andreas Scheuba, Florian Wolf, Martin Funovics, Bernd Gollackner, Anders Wanhainen, Christoph Neumayer, Martin Posch, Christine Brostjan, Wolf Eilenberg
Summary: This study developed a statistical model that takes into account various characteristics of AAA growth and applied it to predict AAA growth. The results demonstrated that the model accurately described the distribution of AAA growth and could be used to predict growth rates and the probability of exceeding a specific threshold for patients.
BRITISH JOURNAL OF SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)