Article
Medicine, General & Internal
Roberto Chiesa, Enrico Rinaldi, Andrea Kahlberg, Sarah Tinaglia, Annarita Santoro, Giovanni Colacchio, Germano Melissano
Summary: This study aimed to determine whether the contemporary approach for thoracoabdominal aortic aneurysm repair influenced the outcomes. Retrospective analysis was conducted and patients were divided into two groups for comparison. The results showed a significant reduction in in-hospital mortality and spinal cord ischemia in the second group, which utilized adjuncts systematically.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Carlos Perez-Vega, Ricardo A. Domingo, Shashwat Tripathi, Andres Ramos-Fresnedo, Jaime L. Martinez Santos, Rudy J. Rahme, William D. Freeman, Sukhwinder S. Sandhu, David A. Miller, Bernard R. Bendok, Waleed Brinjikji, Alfredo Quinones-Hinojosa, Fredric B. Meyer, Rabih G. Tawk, W. Christopher Fox
Summary: Patients with Loeys-Dietz syndrome have an increased risk of intracranial aneurysms, especially in those with a history of smoking. The prevalence rate of intracranial aneurysms in this series was 30%. Screening imaging should be considered at diagnosis, and patients should be encouraged to quit smoking. Further studies are needed to determine the risk of aneurysm rupture and treatment considerations in this unique population.
Article
Surgery
Sandrine Darigny, Parla Astarci, Maxime Elens
Summary: This case report highlights the major aortic complications in a male patient with Loeys-Dietz syndrome and the need for multiple surgical procedures to achieve complete recovery.
VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Article
Multidisciplinary Sciences
Taehun Kim, Dayeong Hong, Junhyeok Ock, Sung Jun Park, Younju Rhee, Sangwook Lee, Guk Bae Kim, Dong Hyun Yang, Joon Bum Kim, Namkug Kim
Summary: The new techniques for repairing thoracoabdominal aortic aneurysms using patient-specific 3D-printed graft reconstruction guides have effectively addressed the challenges in positioning and guiding the visceral and segmental arteries. Evaluation based on accuracy, marking time, reproducibility, and surgeon feedback has demonstrated the efficiency and efficacy of these techniques in accurately reconstructing customized grafts.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Jahan Mohebali, Christopher A. Latz, Richard P. Cambria, Virendra Patel, Emel A. Ergul, R. Todd Lancaster, Mark F. Conrad, W. Darrin Clouse
Summary: The study found excellent long-term patency of visceral and renal reconstructions after open TAAA repair, regardless of the reconstructive technique used. There were no significant differences in patency even when target vessel disease was addressed during reconstruction. These findings further support the effective long-term durability of open TAAA repair and are relevant to the ongoing evolution of endovascular strategies.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
Rodolfo V. Rocha, Charles De Mestral, Derrick Y. Tam, Douglas S. Lee, Mohammed Al-Omran, Peter C. Austin, Thomas L. Forbes, Maral Ouzounian, Thomas F. Lindsay
Summary: This study compared the 1-year healthcare costs of endovascular and open repairs for thoracoabdominal aortic aneurysm (TAAA), finding that endovascular repair had higher costs in the first month post-procedure compared to open repair, but no significant differences in costs from 1 to 12 months post-repair. Older age, urgent procedures, and history of stroke were associated with increased costs in the first month postoperatively.
JOURNAL OF VASCULAR SURGERY
(2021)
Review
Respiratory System
Lamia Harik, Christopher Lau
Summary: Thoracoabdominal aortic aneurysms (TAAAs) are associated with high morbidity and mortality rates. Surgical repair is recommended for symptomatic aneurysms and those reaching a certain size or growth threshold. Open repair remains the gold standard, but endovascular repair has become more widely applicable due to technological advancements.
JOURNAL OF THORACIC DISEASE
(2023)
Article
Clinical Neurology
Anna L. Huguenard, Gabrielle W. Johnson, Rupen R. Desai, Joshua W. Osbun, Ralph G. Dacey, Alan C. Braverman
Summary: This study evaluated the incidence of phenotypic abnormalities, craniofacial features, and Chiari malformation type I (CM-I) in patients with Loeys-Dietz syndrome (LDS), as well as explored possible risk factors for the development of intracranial aneurysms. The results showed a significant association between CM-I and the presence of intracranial aneurysms, while the craniofacial severity index (CFI) was not correlated. Therefore, surveillance for intracranial aneurysms should be conducted in all LDS patients, regardless of the severity of their phenotypes.
JOURNAL OF NEUROSURGERY
(2023)
Review
Pediatrics
Francesco Baldo, Laura Morra, Agnese Feresin, Flavio Faletra, Yasmin Al Naber, Luigi Memo, Laura Travan
Summary: Loeys-Dietz syndrome (LDS) is a rare connective tissue disorder characterized by cardiovascular manifestations, craniofacial and skeletal features, and other abnormalities. Early diagnosis is crucial in preventing complications. Case reports and literature review suggest that early intervention can modify the natural history of the disease, highlighting the multiple benefits of early diagnosis.
ITALIAN JOURNAL OF PEDIATRICS
(2022)
Article
Surgery
Luis Cajas-Monson, Mario D'Oria, Emanuel Tenorio, Bernardo C. Mendes, Gustavo S. Oderich, Randall R. DeMartino
Summary: This study reviewed the association of renal function on patient survival after fenestrated and branched endovascular aneurysm repair (FB-EVAR), with findings suggesting that selected patients with CKD 4-5 may have similar short- and long-term mortality compared to those with normal to moderate renal dysfunction. Renal dysfunction, although a major contraindication for open repair, might not be as prohibitive for endovascular repair in well-selected patients.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Felipe Sanchez Tijmes, Victor Siang Hua Chan, Jillian Murphy, Dalia Abdulmonem L. Hashem, Kate Hanneman, Rachel M. Wald, Paaladinesh Thavendiranathan, Maral Ouzounian, Erwin Oechslin, Gauri R. Karur
Summary: This study evaluated the impact of mitral annular disjunction (MAD) on cardiac magnetic resonance imaging in Loeys-Dietz Syndrome (LDS) and found that MAD is highly prevalent in LDS, associated with progressive aortic dilatation and aortic events at younger age. MAD may be a marker of disease severity necessitating close surveillance.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Donald Adam, Mauro Iafrancesco, Maciej Juszczak, Martin Claridge, David Quinn, Eshan Senanayake, Paul Clift, Jorge Mascaro
Summary: A study conducted at an aortic centre in the UK showed that descending thoracic and thoracoabdominal aortic replacement in patients with Marfan syndrome and Loeys-Dietz syndrome can be performed with low perioperative morbidity and mortality, satisfactory long-term survival, and low requirement for distal reintervention.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Panagiotis Doukas, Cathryn Bassett, Hanif Krabbe, Jelle Frankort, Michael J. Jacobs, Moustafa Elfeky, Alexander Gombert
Summary: This study evaluated the diagnostic capacity of intestinal fatty acid-binding protein (IFABP) levels in detecting visceral malperfusion after open thoracoabdominal aortic repairs. The results showed that elevated IFABP concentrations in serum accurately detected visceral malperfusion during the first 12 hours after surgery. Therefore, IFABP measurements can be a valuable tool for reliable and timely detection of visceral malperfusion.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Genetics & Heredity
Konstantinia Almpani, Denise K. Liberton, Priyam Jani, Cyrus Keyvanfar, Rashmi Mishra, Natasha Curry, Pamela Orzechowski, Pamela A. Frischmeyer-Guerrerio, Janice S. Lee
Summary: The study provides a comprehensive analysis of craniofacial and functional features among LDS subtypes and SGS, revealing developmental abnormalities associated with mutation variants along the TGF-beta signalling pathway. Results show that LDS type 2 patients exhibit the greatest craniofacial shape variation, while SGS patients cluster distinctly. The study highlights the impact of mutations on the TGF-beta pathway on craniofacial anomalies with severe downstream effects on cranial base structures and clinical phenotypes.
JOURNAL OF MEDICAL GENETICS
(2022)
Article
Surgery
Enrico Rinaldi, Diletta Loschi, Annarita Santoro, Victor Bilman, Dhaniel Morgado De Freitas, Carlo Campesi, Sarah Tinaglia, Roberto Chiesa, Germano Melissano
Summary: This study investigated the outcomes of thoracoabdominal aortic aneurysm (TAAA) patients with shaggy aorta (SA) treated with open surgical repair (OSR). The results showed that patients with SA had worse postoperative outcomes, including higher in-hospital mortality, postoperative acute renal failure, and postoperative embolization, compared to patients without SA. However, the grade of SA did not significantly impact postoperative outcomes.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Pierleone Lucatelli, Marco Cini, Antonio Benvenuti, Luca Saba, Giulio Tommasino, Giulia Guaccio, Graham Munneke, Eugenio Neri, Carmelo Ricci
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Eugenio Neri, Enrico Tucci, Giulia Guaccio, Luigi Muzzi
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pierleone Lucatelli, Marco Cini, Giulio Tommasino, Antonio Benvenuti, Giulia Guaccio, Stefano Bascetta, Eugenio Neri, Carmelo Ricci
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Eugenio Neri, Enrico Tucci, Giulio Tommasino, Luigi Muzzi
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
(2018)
Editorial Material
Surgery
Claudio Ceccherini, Carmelo Ricci, Marco Cini, Francesco Vigni, Sara Leonini, Giulio Tommasino, Luigi Muzzi, Enrico Tucci, Antonio Benvenuti, Eugenio Neri
JOURNAL OF ENDOVASCULAR THERAPY
(2013)
Article
Computer Science, Information Systems
Simone Bonechi, Paolo Andreini, Alessandro Mecocci, Nicola Giannelli, Franco Scarselli, Eugenio Neri, Monica Bianchini, Giovanna Maria Dimitri
Summary: The automatic segmentation of the aorta using 2D convolutional neural networks and 3D CT scans as input is presented in this paper. A semi-automated approach was used to obtain 3D annotations for a set of CT images, and two different network architectures were compared for segmentation on three CT views. The results show promising accuracy and efficiency of the neural networks in providing aortic segmentation.
Article
Surgery
Gioele Simonte, Giacomo Isernia, Emanuele Gatta, Eugenio Neri, Gianbattista Parlani, Laura Candeloro, Sara Schiavon, Gabriele Pagliariccio, Marco Cini, Massimo Lenti, Luciano Carbonari, Carmelo Ricci
Summary: This study evaluated the early outcomes of a single manufacturer custom-made inner-branched endograft in a multicenter Italian experience. The results showed that the inner branched technology has wide applicability and achieved good clinical success in complex aortic repair.
JOURNAL OF VASCULAR SURGERY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Amato Santoro, Maria Barilli, Carmine Marallo, Matteo Cameli
EUROPEAN HEART JOURNAL SUPPLEMENTS
(2022)
Article
Surgery
Veronica Lorenz, Carmelo Ricci, Marco Cini, Laura Candeloro, Giulio Tommasino, Luigi Muzzi, Enrico Tucci, Eugenio Neri
Summary: An 80-year-old man with diffuse vascular atherosclerosis and a deep ulcerative lesion at the level of the aortic arch concavity was not eligible for open surgical repair. However, a totally endovascular branched arch repair involving transapical delivery of the three branches was successful.
JOURNAL OF VASCULAR SURGERY CASES INNOVATIONS AND TECHNIQUES
(2023)
Article
Cardiac & Cardiovascular Systems
Massimo Fineschi, Francesco Contorni, Arcangelo Carrera, Eugenio Neri
Summary: In this case, a patient with a biological Bentall graft presented with severely deteriorated aortic prosthetic valve and tube dissection. Since redo surgery was not feasible, a valve-in-valve (ViV) procedure was performed to treat both the valve and tube problems. The procedure was successful and subsequent imaging showed closure of the graft wall false lumen.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Arcangelo Carrera, Francesco Contorni, Andrea Gambacciani, Eugenio Neri
Summary: This case report describes a successful treatment of stable exertional angina due to late stenosis of the coronary prosthetic conduit using trans-femoral percutaneous angioplasty and off-label implantation of a balloon-expandable bare-metal stent designed for peripheral artery disease. A multimodality imaging approach was essential for lesion assessment and procedural planning.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Eugenio Neri, Luigi Muzzi, Enrico Tucci, Marco Cini, Lucio Barabesi, Giulio Tommasino, Carmelo Ricci
Summary: The study retrospectively analyzed 146 patients who underwent aortic arch-replacement procedures using the Siena graft, showing that the device provides a reliable platform for the treatment of diffuse aneurysmal disease. It offers flexibility in managing extended aortic lesions and allows for selection of the most appropriate treatment approach.
Review
Cardiac & Cardiovascular Systems
Alessandro Iadanza, Flavio D'Ascenzi, Andrea Torrisi, Giuseppe Sinicropi, Eugenio Neri, Sonia Bernazzali, Massimo Maccherini, Carlo Pierli
STRUCTURAL HEART-THE JOURNAL OF THE HEART TEAM
(2019)
Article
Surgery
Luigi Muzzi, Giulio Tommasino, Giulia Guaccio, Enrico Tucci, Franco Roviello, Eugenio Neri
ANNALS OF VASCULAR SURGERY
(2017)
Article
Cardiac & Cardiovascular Systems
C. Ricci, C. Ceccherini, M. Cini, F. Vigni, S. Leonini, A. Puliti, A. Benvenuti, E. Tucci, G. Tommasino, L. Muzzi, E. Neri
JOURNAL OF CARDIOVASCULAR SURGERY
(2013)
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)
