Article
Cardiac & Cardiovascular Systems
Steele C. Butcher, Benjamin Essayagh, Ewout W. Steyerberg, Giovanni Benfari, Clemence Antoine, Francesco Grigioni, Thierry Le Tourneau, Jean-Christian Roussel, Aniek van Wijngaarden, Nina Ajmone Marsan, Christophe Tribouilloy, Dan Rusinaru, Aviram Hochstadt, Yan Topilsky, Hector Michelena, Victoria Delgado, Jeroen J. Bax, Maurice Enriquez-Sarano
Summary: This study examined the impact of secondary outcome determinants on post-operative survival in patients with degenerative mitral regurgitation (DMR) and found that the number of these determinants was independently associated with increased mortality after surgery, providing better outcome discrimination than traditional indications for surgery.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Elisabetta Lapenna, Teodora Nisi, Davide Carino, Marta Bargagna, Stefania Ruggeri, Edoardo Zancanaro, Benedetto Del Forno, Davide Schiavi, Eustachio Agricola, Alessandro Castiglioni, Ottavio Alfieri, Michele De Bonis
Summary: In patients with HOCM and moderate septal thickness with SAM-related MR, addressing abnormalities of the MV apparatus may become necessary as septal hypertrophy decreases. However, performing myectomy alone appears to be associated with a better postoperative course and a trend towards lower cardiac mortality at follow-up, despite a higher rate of residual moderate MR.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Heemoon Lee, Dong Seop Jeong, Wook Sung Kim, Kiick Sung, Keumhee Chough Carriere, Sung-Ji Park, Pyo Won Park
Summary: The study found that prophylactic TAP in patients with mild TR who underwent mitral valve repair may not have a beneficial effect on TR progression. Further large studies are necessary to define the role of prophylactic TAP in mild TR.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Juliano Lentz Carvalho, Hartzell V. Schaff, Rick A. Nishimura, Steve R. Ommen, Jeffrey B. Geske, Brian D. Lahr, Darrell B. Newman, Joseph A. Dearani
Summary: This study investigated the mitral valve leaflet length and outcomes of patients undergoing septal myectomy for obstructive hypertrophic cardiomyopathy. The results showed that patients with hypertrophic cardiomyopathy have slightly elongated mitral valve leaflets. However, the length of the leaflets is not significantly associated with left ventricular outflow tract gradient relief or postoperative outcomes.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Changpeng Song, Jingang Cui, Xinxin Zheng, Jie Lu, Xinli Guo, Shuiyun Wang, Xiaohong Huang
Summary: Obstructive hypertrophic cardiomyopathy (oHCM) and mitral valve (MV) prolapse (MVP) are two conditions that can cause symptomatic heart failure and sudden cardiac death. This study investigated the clinical characteristics and surgical outcomes of patients with oHCM and MVP. Patients with MVP had more severe symptoms and higher incidence of mitral regurgitation, atrial fibrillation, and ventricular tachycardia. Surgery combining mitral valve repair or replacement with myectomy effectively relieved left ventricular outflow tract gradients and mitral regurgitation.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sri Harsha Patlolla, Hartzell Schaff, Rick A. Nishimura, Jeffrey B. Geske, Brian D. Lahr, Alexander T. Lee, Mackram F. Eleid, Steve R. Ommen, Joseph A. Dearani
Summary: This study found a high prevalence of MAC in patients with obstructive hypertrophic cardiomyopathy, lower survival rates in MAC patients, and identified MAC as an independent predictor of poor survival after septal myectomy.
ANNALS OF THORACIC SURGERY
(2022)
Article
Medicine, Research & Experimental
Monica De Gaspari, Mariachiara Mazzucato, Maria Bueno Marinas, Annalisa Angelini, Chiara Calore, Martina Perazzolo Marra, Kalliopi Pilichou, Domenico Corrado, Gaetano Thiene, Stefania Rizzo, Cristina Basso
Summary: The study validates the existence of a muscular mitral-aortic discontinuity during surgery in patients with hypertrophic cardiomyopathy. It reveals that the left atrial myocardium extends into the inter-valvular fibrosa, and its length decreases with age.
LABORATORY INVESTIGATION
(2023)
Article
Cardiac & Cardiovascular Systems
Dae-Young Kim, Jiwon Seo, Iksung Cho, Geu-Ru Hong, Jong-Won Ha, Chi Young Shim
Summary: This study investigates the prognostic implication of mitral valve disease and its progression in East Asian patients with HCM. The presence and progression of MR are associated with a poor prognosis in patients with HCM.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Peijian Wei, Jian Liu, Jiexu Ma, Yanjun Liu, Tong Tan, Hongxiang Wu, Wei Zhu, Zhao Chen, Jimei Chen, Jian Zhuang, Huiming Guo
Summary: This study aimed to evaluate the safety and efficacy of thoracoscopic trans-mitral septal myectomy in elderly patients. The results showed that thoracoscopic surgery can achieve satisfactory treatment outcomes similar to those of young patients in selected elderly patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Fangyu Liu, Yulin Wang, Ye Yang, Hao Lai, Kai Song, Chunsheng Wang, Qiang Ji
Summary: The study suggests that in HOCM patients with severe MR but without intrinsic MV disease, mitral subvalvular management during septal myectomy may lead to reduced MR severity, lower outflow tract gradient, and decreased incidence of SAM.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Peijian Wei, Jiexu Ma, Tong Tan, Wei Zhu, Haiyun Yuan, Jian Zhuang, Jian Liu, Huiming Guo
Summary: In this study, the clinical outcomes of thoracoscopic trans-mitral myectomy were compared with transaortic myectomy in patients with hypertrophic obstructive cardiomyopathy. The results showed that patients in the trans-mitral group had a higher rate of early extubation, shorter ventilation duration, and lower transfusion rate compared to the transaortic group. There were no significant differences in in-hospital mortality, low cardiac output syndrome, or permanent pacemaker implantations between the two groups. Thoracoscopic trans-mitral myectomy effectively relieved left ventricular outflow tract obstruction without increasing major complications.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Andrea Frustaci, Valentino Borghetti, Samuele Pentiricci, Romina Verardo, Rossella Scialla, Matteo Antonio Russo
Summary: This study highlights the importance of genetic screening for Fabry disease before considering surgical treatment for hypertrophic obstructive cardiomyopathy. By analyzing the genes of a 59-year-old man, it was found that he had Fabry disease cardiomyopathy, which helped avoid surgical risks. This research is of significant importance for preventing surgical complications.
Article
Cardiac & Cardiovascular Systems
Zining Wu, Changrong Nie, Changsheng Zhu, Yanhai Meng, Qiulan Yang, Tao Lu, Zhengyang Lu, Xiaoxi Liu, Shuiyun Wang
Summary: This study investigates the prognosis value and impact on valve function of mitral annular calcification (MAC) based on computed tomography (CT) diagnosis after myectomy for hypertrophic obstructive cardiomyopathy (OHCM). Results suggest that patients with MAC have worse prognosis and more recurrent mitral valve regurgitation after septal myectomy.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Stefanos Sakellaropoulos, Stefano Svab, Muhemin Mohammed, Lekaditi Dimitra, Andreas Mitsis
Summary: Hypertrophic cardiomyopathy is a common inherited heart disease, particularly among young athletes, caused primarily by genetic mutations. It is crucial to examine mitral valve apparatus and identify mitral valve abnormalities in HCM patients, as these abnormalities can affect diagnosis and treatment of the disease.
CURRENT PROBLEMS IN CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Jing Fang, Yani Liu, Ying Zhu, Rui Li, Rui Wang, Dao Wen Wang, Yunhu Song, Chenhe Li, Yue Chen, Lin Cheng, Kangchao Zheng, Yun Zhao, Shiliang Li, Cai Cheng, Liming Xia, Xiaoping Chen, Song Wan, Xiang Wei
Summary: This study evaluated the clinical utility of a novel procedure called transapical beating-heart septal myectomy (TA-BSM) for hypertrophic obstructive cardiomyopathy (HOCM). After 3 months of follow-up, 42 out of 46 patients achieved procedural success with significant improvement in left ventricular outflow tract obstruction and mitral regurgitation. In conclusion, TA-BSM is a safe and efficient minimally invasive surgical technique that reduces surgical trauma.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Anita Nguyen, Hartzell V. Schaff, Rick A. Nishimura, Joseph A. Dearani, Jeffrey B. Geske, Brian D. Lahr, Steve R. Ommen
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2018)
Article
Cardiac & Cardiovascular Systems
Sameh M. Said, Zaid M. Abdelsattar, Hartzell V. Schaff, Kevin L. Greason, Richard C. Daly, Alberto Pochettino, Lyle D. Joyce, Joseph A. Dearani
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2018)
Article
Cardiac & Cardiovascular Systems
Nishant Saran, Sameh M. Said, Hartzell V. Schaff, Simon Maltais, John M. Stulak, Kevin L. Greason, Richard C. Daly, Alberto Pochettino, Katherine S. King, Joseph A. Dearani
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Pierre Olivier Dionne, Mackram F. Eleid, Hartzell V. Schaff, Simon Maltais
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Article
Cardiac & Cardiovascular Systems
Nishant Saran, Chaim Locker, Sameh M. Said, Richard C. Daly, Simon Maltais, John M. Stulak, Kevin L. Greason, Alberto Pochettino, Hartzell V. Schaff, Joseph A. Dearani, Lyle D. Joyce, Brian D. Lahr, David L. Joyce
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Article
Cardiac & Cardiovascular Systems
Amit P. Java, Kevin L. Greason, Angela Dispenzieri, Martha Grogan, Katherine S. King, Joseph J. Maleszewski, Richard C. Daly, Mackram F. Eleid, Alberto Pochettino, Hartzell V. Schaff
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Hartzell V. Schaff, Anita Nguyen
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Editorial Material
Cardiac & Cardiovascular Systems
Hao Cui, Anita Nguyen, Hartzell V. Schaff
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2018)
Article
Medicine, General & Internal
Meghana R. K. Helder, Hartzell V. Schaff, Thomas A. Foley, Nandan S. Anavekar, David R. Deyle, Alberto Pochettino, Heidi M. Connolly
MAYO CLINIC PROCEEDINGS
(2018)
Article
Cardiac & Cardiovascular Systems
Krithika Ramaprabhu, Nishant Saran, Joseph Dearani, Brian Lahr, Hartzell Schaff, Kevin Greason, Suraj Yalamuri, Chirantan Mangukia, John Stulak, Gabor Bagameri, Juan Crestanello, Alberto Pochettino
Summary: This study compared the safety and efficacy of direct cannulation of the ascending aorta with cannulation of peripheral arteries in the treatment of type A dissection patients. The results showed that direct cannulation of the ascending aorta is a safe strategy for arterial cannulation, allowing for rapid cannulation and antegrade perfusion.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Alejandra Castro-Varela, Hartzell Schaff
Summary: After analyzing the characteristics of top-cited articles in JTCVS over the past 6 decades, it was found that the majority of the most-cited papers focused on topics in adult cardiac surgery and general thoracic surgery. These articles were presented mainly at the Annual Meeting of the American Association for Thoracic Surgery. The use of citations as a measure of impact has limitations, and alternative metrics may provide a more equitable evaluation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Sri Harsha Patlolla, Hartzell V. V. Schaff, Rick A. A. Nishimura, Mackram F. F. Eleid, Jeffrey B. B. Geske, Steve R. R. Ommen
Summary: This study found that minority racial and ethnic groups were less likely to receive septal reduction therapies for obstructive hypertrophic cardiomyopathy. Hispanic and other ethnic patients undergoing these therapies had significantly higher in-hospital mortality and complication rates. Further research is needed to understand these differences.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Juan A. Crestanello, Kevin Greason, Mohamed Elsisy, Brian Lahr, Gabor Bagameri, Richard Daly, John Stulak, Joseph Dearani, Hartzell Schaff
Summary: This study examined the indications and temporal trends for delayed sternal closure (DSC) after cardiac surgery, as well as factors associated with time to chest closure and its impact on short-term and long-term outcomes. Longer time to chest closure was associated with increased rates of operative complications and operative mortality, but did not have a statistically significant association with long-term survival.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Siddharth Pahwa, Nishant Saran, Alberto Pochettino, Hartzell Schaff, John Stulak, Kevin Greason, Richard Daly, Juan Crestanello, Katherine King, Joseph Dearani
Summary: For functional tricuspid regurgitation (fTR), tricuspid valve repair surgery seems to have better early and late outcomes. Patients undergoing tricuspid valve replacement (TVR) had higher early mortality, renal failure, and longer hospital stay compared to those undergoing tricuspid valve repair (TVr), with worse survival in the TVR cohort.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Anesthesiology
Patrick M. Wieruszewski, Scott D. Nei, Simon Maltais, Hartzell V. Schaff, Erica D. Wittwer
Article
Cardiac & Cardiovascular Systems
Soh Hosoba, Toshiaki Ito, Makoto Mori, Riku Kato, Koh Kajiyama, Shogo Maeda, Yuji Nakai, Yoshihiro Morishita
Summary: This study describes the approach and perioperative outcomes of totally endoscopic isolated and concomitant surgical aortic valve replacement (AVR) using various valve types. The results demonstrate that endoscopic AVR can safely address concomitant valve diseases.
ANNALS OF THORACIC SURGERY
(2024)