JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PI3 Kinase δ Is a Key Regulator of Synoviocyte Function in Rheumatoid Arthritis

(2012) Beatrix Bartok et al.   AMERICAN JOURNAL OF PATHOLOGY

DNA methylome signature in rheumatoid arthritis

(2012) Kazuhisa Nakano et al.   ANNALS OF THE RHEUMATIC DISEASES

Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well as therapeutic targets

(2011) Daphne de Launay et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

(2011) Aleksander M Grabiec et al.   ANNALS OF THE RHEUMATIC DISEASES

STAT3 Protein Promotes T-cell Survival and Inhibits Interleukin-2 Production through Up-regulation of Class O Forkhead Transcription Factors

(2011) Hyun-Mee Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor

(2011) V M Renault et al.   ONCOGENE

PI3K  Plays a Critical Role in Neutrophil Activation by Immune Complexes

(2011) S. Kulkarni et al.   Science Signaling

Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials

(2010) M. G. H. van de Sande et al.   ANNALS OF THE RHEUMATIC DISEASES

The Extending Network of FOXO Transcriptional Target Genes

(2010) Kristan E. van der Vos et al.   ANTIOXIDANTS & REDOX SIGNALING

Integrating Opposing Signals Toward Forkhead Box O

(2010) Maaike C.W. van den Berg et al.   ANTIOXIDANTS & REDOX SIGNALING

PI3K p110  regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

(2010) D. R. Soond et al.   BLOOD

Growth Factor Stimulation Induces Cell Survival by c-Jun·ATF2-dependent Activation of Bcl-XL

(2010) Ahmad Salameh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

(2010) Weiming Ouyang et al.   NATURE IMMUNOLOGY

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

Cell death in rheumatoid arthritis

(2009) Adelheid Korb et al.   APOPTOSIS

FoxO4 Inhibits NF-κB and Protects Mice Against Colonic Injury and Inflammation

(2009) Wen Zhou et al.   GASTROENTEROLOGY

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors

(2009) Ahmed Essaghir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional regulation ofCLMPmRNA is controlled by tristetraprolin in response to TNFα via c-Jun N-terminal kinase signalling

(2008) Kit-Ling Sze et al.   BIOCHEMICAL JOURNAL

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Foxo in the immune system

(2008) S L Peng   ONCOGENE