Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination

Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB

(2013) Svetlana Frank et al.   ANNALS OF THE RHEUMATIC DISEASES

Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine-Induced Cartilage Degradation

(2013) Kirsty L. Culley et al.   ARTHRITIS AND RHEUMATISM

Matrix Metalloproteinase 13 Expression in Response to Double-Stranded RNA in Human Chondrocytes

(2013) Marta Radwan et al.   ARTHRITIS AND RHEUMATISM

Effects of a proteasome inhibitor on the NF-κB signalling pathway in experimental osteoarthritis

(2013) R Quan et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo

(2012) Annika Burleigh et al.   ARTHRITIS AND RHEUMATISM

Cartilage development and degeneration: a Wnt Wnt situation

(2012) Katherine Ann Staines et al.   CELL BIOCHEMISTRY AND FUNCTION

Regulation of NF-κB by deubiquitinases

(2012) Edward W. Harhaj et al.   IMMUNOLOGICAL REVIEWS

The ubiquitin proteasome system and efficacy of proteasome inhibitors in diseases

(2012) Selvarajan Chitra et al.   International Journal of Rheumatic Diseases

Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues

(2012) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Tyrosine Nitration of PA700 Links Proteasome Activation to Endothelial Dysfunction in Mouse Models with Cardiovascular Risk Factors

(2012) Jian Xu et al.   PLoS One

Diverse ubiquitin signaling in NF-κB activation

(2012) Kazuhiro Iwai   TRENDS IN CELL BIOLOGY

Age-dependent alteration of TGF-β signalling in osteoarthritis

(2011) Peter M. van der Kraan et al.   CELL AND TISSUE RESEARCH

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs)

(2011) Fernando Lopitz-Otsoa et al.   Journal of Proteomics

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation

(2010) M. J. Barter et al.   ANNALS OF THE RHEUMATIC DISEASES

The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats

(2010) Evangelia Yannaki et al.   ARTHRITIS AND RHEUMATISM

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Regulatory mechanisms involved in the control of ubiquitin homeostasis

(2010) Y. Kimura et al.   JOURNAL OF BIOCHEMISTRY

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes

(2010) Matt J. Barter et al.   MATRIX BIOLOGY

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling

(2009) Jin Nam et al.   PLoS One

Differential Toll-like receptor-dependent collagenase expression in chondrocytes

(2008) Q Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Polyubiquitin chains: functions, structures, and mechanisms

(2008) W. Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

FLN29 Deficiency Reveals Its Negative Regulatory Role in the Toll-like Receptor (TLR) and Retinoic Acid-inducible Gene I (RIG-I)-like Helicase Signaling Pathway

(2008) Takahito Sanada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-κBp65-specific siRNA

(2007) L.X. Chen et al.   OSTEOARTHRITIS AND CARTILAGE