A Pilot Trial Targeting the ICOS-ICOS-L Pathway in Nonhuman Primate Kidney Transplantation

2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+T cell responses

(2014) Danya Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ICOS Controls the Pool Size of Effector-Memory and Regulatory T Cells

(2014) Y. Burmeister et al.   JOURNAL OF IMMUNOLOGY

Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival Without a Requirement for Memory T Cell Depletion

(2013) D. J. Lo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Long-Term Belatacept Exposure Maintains Efficacy and Safety at 5 Years: Results From the Long-Term Extension of the BENEFIT Study

(2013) L. Rostaing et al.   AMERICAN JOURNAL OF TRANSPLANTATION

ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner

(2013) Jian Zheng et al.   PLoS One

Belatacept-Based Regimens Are Associated With Improved Cardiovascular and Metabolic Risk Factors Compared With Cyclosporine in Kidney Transplant Recipients (BENEFIT and BENEFIT-EXT Studies)

(2011) Yves Vanrenterghem et al.   TRANSPLANTATION

Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression

(2010) D. J. Lo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

ICOS-Dependent and -Independent Functions of Memory CD4 T Cells in Allograft Rejection

(2008) Q.-W. Zhang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Effector Functions of Donor-Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts

(2008) A. D. Schenk et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Donor-Reactive CD8 Memory T Cells Infiltrate Cardiac Allografts Within 24-h Posttransplant in Naive Recipients

(2008) A. D. Schenk et al.   AMERICAN JOURNAL OF TRANSPLANTATION