Mouse models for studying genetic influences on factors determining smoking cessation success in humans

The Nicotinic Acetylcholine Receptor  5 Subunit Plays a Key Role in Attention Circuitry and Accuracy

(2013) C. D. C. Bailey et al.   JOURNAL OF NEUROSCIENCE

Subjective sleep disturbance during a smoking cessation program: Associations with relapse

(2011) Michele L. Okun et al.   ADDICTIVE BEHAVIORS

Delay discounting in C57BL/6J and DBA/2J mice: Adolescent-limited and life-persistent patterns of impulsivity.

(2011) Jonathan W. Pinkston et al.   BEHAVIORAL NEUROSCIENCE

The effects of galantamine on nicotine withdrawal-induced deficits in contextual fear conditioning in C57BL/6 mice

(2011) Derek S. Wilkinson et al.   BEHAVIOURAL BRAIN RESEARCH

Nicotine ameliorates impairment of working memory in methamphetamine-treated rats

(2011) Hiroyuki Mizoguchi et al.   BEHAVIOURAL BRAIN RESEARCH

Working memory span capacity improved by a D2 but not D1 receptor family agonist

(2011) Isadore S. Tarantino et al.   BEHAVIOURAL BRAIN RESEARCH

Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice

(2011) Dena Kota et al.   BIOCHEMICAL PHARMACOLOGY

Mechanistic insights into nicotine withdrawal

(2011) Michael Paolini et al.   BIOCHEMICAL PHARMACOLOGY

Deconstructing Craving: Dissociable Cortical Control of Cue Reactivity in Nicotine Addiction

(2011) Daniel Scott et al.   BIOLOGICAL PSYCHIATRY

Parallel goal-directed and habitual control of human drug-seeking: Implications for dependence vulnerability.

(2011) Lee Hogarth et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Nicotine restores morphine-induced memory deficit through the D1 and D2 dopamine receptor mechanisms in the nucleus accumbens

(2011) Ronak Azizbeigi et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Depression-related anhedonic behaviors caused by immobilization stress: a comparison with nicotine-induced depression-like behavioral alterations and effects of nicotine and/or “antidepressant” drugs

(2011) Tamaki Hayase   JOURNAL OF TOXICOLOGICAL SCIENCES

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

(2011) Christie D. Fowler et al.   NATURE

Intravenous nicotine self-administration and cue-induced reinstatement in mice: Effects of nicotine dose, rate of drug infusion and prior instrumental training

(2011) Christie D. Fowler et al.   NEUROPHARMACOLOGY

CHRNA3 rs1051730 Genotype and Short-Term Smoking Cessation

(2011) M. R. Munafo et al.   NICOTINE & TOBACCO RESEARCH

Reward-Related Behavioral Paradigms for Addiction Research in the Mouse: Performance of Common Inbred Strains

(2011) Lauren Lederle et al.   PLoS One

Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence

(2011) Catherine Johnson et al.   PLoS One

Distinct contributions of nicotinic acetylcholine receptor subunit  4 and subunit  6 to the reinforcing effects of nicotine

(2011) R. Exley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurobiology of the incubation of drug craving

(2011) Charles L. Pickens et al.   TRENDS IN NEUROSCIENCES

Nicotine acts in the anterior cingulate, but not dorsal or ventral hippocampus, to reverse ethanol-induced learning impairments in the plus-maze discriminative avoidance task

(2010) Danielle Gulick et al.   ADDICTION BIOLOGY

Cognitive effects of nicotine: genetic moderators

(2010) Aryeh I. Herman et al.   ADDICTION BIOLOGY

Smoking cue reactivity across massed extinction trials: Negative affect and gender effects

(2010) Bradley N. Collins et al.   ADDICTIVE BEHAVIORS

Bupropion and Cognitive Behavioral Therapy for Weight-Concerned Women Smokers

(2010) Michele D. Levine   ARCHIVES OF INTERNAL MEDICINE

Heritability of Delay Discounting in Adolescence: A Longitudinal Twin Study

(2010) Andrey P. Anokhin et al.   BEHAVIOR GENETICS

Repeated agmatine treatment attenuates nicotine sensitization in mice: Modulation by α2-adrenoceptors

(2010) Nandkishor Ramdas Kotagale et al.   BEHAVIOURAL BRAIN RESEARCH

Emergence of Dormant Conditioned Incentive Approach by Conditioned Withdrawal in Nicotine Addiction

(2010) Daniel Scott et al.   BIOLOGICAL PSYCHIATRY

Effects of the α4β2 Partial Agonist Varenicline on Brain Activity and Working Memory in Abstinent Smokers

(2010) James Loughead et al.   BIOLOGICAL PSYCHIATRY

Incubation of Cue-Induced Cigarette Craving During Abstinence in Human Smokers

(2010) Gillinder Bedi et al.   BIOLOGICAL PSYCHIATRY

Regulation of the nicotinic receptor alpha7 subunit by chronic stress and corticosteroids

(2010) Richard G. Hunter et al.   BRAIN RESEARCH

Why do patients with schizophrenia smoke?

(2010) Georg Winterer   CURRENT OPINION IN PSYCHIATRY

Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex

(2010) Amir Abdolahi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Addictive Nicotine Alters Local Circuit Inhibition during the Induction of In Vivo Hippocampal Synaptic Potentiation

(2010) T. A. Zhang et al.   JOURNAL OF NEUROSCIENCE

Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline

(2010) Jesper T Andreasen et al.   JOURNAL OF PSYCHOPHARMACOLOGY

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(2010) George Uhl et al.   MOLECULAR MEDICINE

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(2010) Jed Rose et al.   MOLECULAR MEDICINE

High fat diet altered the mechanism of energy homeostasis induced by nicotine and withdrawal in C57BL/6 mice

(2010) Young-Na Hur et al.   MOLECULES AND CELLS

The role of nicotinic acetylcholine receptors in the medial prefrontal cortex and hippocampus in trace fear conditioning

(2010) J.D. Raybuck et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Nicotine ameliorates NMDA receptor antagonist-induced deficits in contextual fear conditioning through high-affinity nicotinic acetylcholine receptors in the hippocampus

(2010) Jessica M. André et al.   NEUROPHARMACOLOGY

Amphetamine Exposure Selectively Enhances Hippocampus-Dependent Spatial Learning and Attenuates Amygdala-Dependent Cue Learning

(2010) Rutsuko Ito et al.   NEUROPSYCHOPHARMACOLOGY

Incubation of conditioned fear in the conditioned suppression model in rats: role of food-restriction conditions, length of conditioned stimulus, and generality to conditioned freezing

(2010) C.L. Pickens et al.   NEUROSCIENCE

Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans

(2010) S. P. David et al.   NICOTINE & TOBACCO RESEARCH

Beta2* nicotinic acetylcholine receptors modulate pain sensitivity in acutely abstinent tobacco smokers

(2010) K. P. Cosgrove et al.   NICOTINE & TOBACCO RESEARCH

Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity

(2010) Jennifer A. Wilking et al.   Pharmacogenetics and Genomics

Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement

(2010) George R Uhl et al.   PHARMACOGENOMICS

Oral nicotine consumption does not affect maternal care or early development in mice but results in modest hyperactivity in adolescence

(2010) Christopher J. Heath et al.   PHYSIOLOGY & BEHAVIOR

Genome Wide Association for Addiction: Replicated Results and Comparisons of Two Analytic Approaches

(2010) Tomas Drgon et al.   PLoS One

Conditional Knockout of NMDA Receptors in Dopamine Neurons Prevents Nicotine-Conditioned Place Preference

(2010) Lei Phillip Wang et al.   PLoS One

Effects of nicotine withdrawal on verbal working memory and associated brain response

(2010) Lawrence H. Sweet et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice

(2010) Candice Contet et al.   PSYCHOPHARMACOLOGY

Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse

(2010) K. J. Jackson et al.   PSYCHOPHARMACOLOGY

Meta-analysis of the acute effects of nicotine and smoking on human performance

(2010) Stephen J. Heishman et al.   PSYCHOPHARMACOLOGY

A systematic review of the Diagnostic and Statistical Manual diagnostic criteria for nicotine dependence

(2009) Joseph DiFranza et al.   ADDICTIVE BEHAVIORS

Genetic influence on human intelligence (Spearman'sg): How much?

(2009) Thomas J. Bouchard   ANNALS OF HUMAN BIOLOGY

ADHD and Smoking

(2009) Francis Joseph McClernon et al.   Annals of the New York Academy of Sciences

Molecular Genetics of Addiction and Related Heritable Phenotypes

(2009) George R. Uhl et al.   Annals of the New York Academy of Sciences

Measurement of affective state during chronic nicotine treatment and withdrawal by affective taste reactivity in mice: The role of endocannabinoids

(2009) Victoria C. Wing et al.   BIOCHEMICAL PHARMACOLOGY

Preclinical pharmacology of the α4β2 nAChR partial agonist varenicline related to effects on reward, mood and cognition

(2009) Hans Rollema et al.   BIOCHEMICAL PHARMACOLOGY

d-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: A pilot investigation

(2009) Elizabeth J. Santa Ana et al.   DRUG AND ALCOHOL DEPENDENCE

Smoking and smoking cessation in disadvantaged women: Assessing genetic contributions

(2009) George R. Uhl et al.   DRUG AND ALCOHOL DEPENDENCE

Working memory deficits predict short-term smoking resumption following brief abstinence

(2009) Freda Patterson et al.   DRUG AND ALCOHOL DEPENDENCE

Nicotine withdrawal-induced deficits in trace fear conditioning in C57BL / 6 mice - a role for high-affinity β2 subunit-containing nicotinic acetylcholine receptors

(2009) J. D. Raybuck et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits

(2009) Jennifer A. Davis et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Serotonin transporter genotype and depressive symptoms moderate effects of nicotine on spatial working memory.

(2009) Joshua M. Carlson et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Appetite control and energy balance regulation in the modern world: reward-driven brain overrides repletion signals

(2009) H Zheng et al.   INTERNATIONAL JOURNAL OF OBESITY

Dramatically Decreased Cocaine Self-Administration in Dopamine But Not Serotonin Transporter Knock-Out Mice

(2009) M. Thomsen et al.   JOURNAL OF NEUROSCIENCE

The Role of  6-Containing Nicotinic Acetylcholine Receptors in Nicotine Reward and Withdrawal

(2009) K. J. Jackson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Nicotine improves ethanol-induced memory impairment: The role of dorsal hippocampal NMDA receptors

(2009) Ameneh Rezayof et al.   LIFE SCIENCES

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(2009) Tomas Drgon et al.   MOLECULAR MEDICINE

Dopamine Enables In Vivo Synaptic Plasticity Associated with the Addictive Drug Nicotine

(2009) Jianrong Tang et al.   NEURON

Enhanced nicotine sensitivity in nociceptin/orphanin FQ receptor knockout mice

(2009) Kazuto Sakoori et al.   NEUROPHARMACOLOGY

Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats

(2009) Krista Spiller et al.   NEUROPHARMACOLOGY

The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion

(2009) K.J. Jackson et al.   NEUROPHARMACOLOGY

Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice

(2009) Kia J. Jackson et al.   NEUROPHARMACOLOGY

Dopaminergic Signaling Mediates the Motivational Response Underlying the Opponent Process to Chronic but Not Acute Nicotine

(2009) Taryn E Grieder et al.   NEUROPSYCHOPHARMACOLOGY

The Hippocampus and Cingulate Cortex Differentially Mediate the Effects of Nicotine on Learning Versus on Ethanol-Induced Learning Deficits Through Different Effects at Nicotinic Receptors

(2009) Danielle Gulick et al.   NEUROPSYCHOPHARMACOLOGY

Nicotine and extinction of fear conditioning

(2009) G.A. Elias et al.   NEUROSCIENCE

Sex differences in response to nicotine in C57Bl/6:129SvEv mice

(2009) Carolina Isiegas et al.   NICOTINE & TOBACCO RESEARCH

Genetics of Tracking of Body Mass Index from Birth to Late Middle Age: Evidence from Twin and Family Studies

(2009) Karri Silventoinen et al.   Obesity Facts

Promise of pharmacogenomics in smoking cessation

(2009) George R Uhl   PHARMACOGENOMICS

Stress-induced hyperthermia is reduced by rapid-acting anxiolytic drugs independent of injection stress in rats

(2009) Christiaan H. Vinkers et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of nicotine on novelty detection and memory recognition performance: double-blind, placebo-controlled studies of smokers and nonsmokers

(2009) Brett Froeliger et al.   PSYCHOPHARMACOLOGY

Molecular Genetics of Successful Smoking Cessation

(2008) George R. Uhl et al.   ARCHIVES OF GENERAL PSYCHIATRY

Genome-Wide Association for Methamphetamine Dependence

(2008) George R. Uhl et al.   ARCHIVES OF GENERAL PSYCHIATRY

Nicotine enhances context learning but not context-shock associative learning.

(2008) Justin W. Kenney et al.   BEHAVIORAL NEUROSCIENCE

Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice.

(2008) Jonathan D. Raybuck et al.   BEHAVIORAL NEUROSCIENCE

Cannabinoid receptor ligands suppress memory-related effects of nicotine in the elevated plus maze test in mice

(2008) Grazyna Biala et al.   BEHAVIOURAL BRAIN RESEARCH

Nicotine withdrawal disrupts both foreground and background contextual fear conditioning but not pre-pulse inhibition of the acoustic startle response in C57BL/6 mice

(2008) J ANDRE et al.   BEHAVIOURAL BRAIN RESEARCH

Anxiety-like behavior during nicotine withdrawal predict subsequent nicotine consumption in adolescent C57BL/6 mice

(2008) Alex C. Manhães et al.   BEHAVIOURAL BRAIN RESEARCH

Nicotinic α7- or β2-containing receptor knockout: Effects on radial-arm maze learning and long-term nicotine consumption in mice

(2008) Edward D. Levin et al.   BEHAVIOURAL BRAIN RESEARCH

Allelic Variation of Calsyntenin 2 (CLSTN2) Modulates the Impact of Developmental Tobacco Smoke Exposure on Mnemonic Processing in Adolescents

(2008) Leslie K. Jacobsen et al.   BIOLOGICAL PSYCHIATRY

Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples

(2008) Catherine Johnson et al.   BMC Medical Genetics

Variation in Nicotine Consumption in Inbred Mice Is Not Linked to Orosensory Ability

(2008) A. Rebecca Glatt et al.   CHEMICAL SENSES

Effects of smoking abstinence on reaction time variability in smokers with and without ADHD: An ex-Gaussian analysis

(2008) Scott H. Kollins et al.   DRUG AND ALCOHOL DEPENDENCE

Effect of forced chronic oral nicotine exposure on intravenous self-administration and rewarding properties of acute nicotine

(2008) Anne Tammimäki et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning

(2008) Y. S. Mineur et al.   GENES BRAIN AND BEHAVIOR

Prodynorphin gene disruption increases the sensitivity to nicotine self-administration in mice

(2008) Lola Galeote et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

New operant model of nicotine-seeking behaviour in mice

(2008) Elena Martín-García et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Association Between Trauma Exposure and Smoking in a Population-Based Sample of Young Adults

(2008) Miguel E. Roberts et al.   JOURNAL OF ADOLESCENT HEALTH

Efficacy of a Nicotine (4 mg)-Containing Lozenge on the Cognitive Impairment of Nicotine Withdrawal

(2008) Giuseppe Atzori et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Modulation of Hippocampus-Dependent Learning and Synaptic Plasticity by Nicotine

(2008) Justin W. Kenney et al.   MOLECULAR NEUROBIOLOGY

Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice

(2008) Danielle Gulick et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice

(2008) A STOKER et al.   NEUROPHARMACOLOGY

The selective nicotinic acetylcholine receptor α7 agonist JN403 is active in animal models of cognition, sensory gating, epilepsy and pain

(2008) Dominik Feuerbach et al.   NEUROPHARMACOLOGY

DAT Genotype Modulates Brain and Behavioral Responses Elicited by Cigarette Cues

(2008) Teresa R Franklin et al.   NEUROPSYCHOPHARMACOLOGY

Opposing actions of chronic stress and chronic nicotine on striatal function in mice

(2008) Ramiro Salas et al.   NEUROSCIENCE LETTERS

Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice

(2008) Barbara J. Caldarone et al.   NEUROSCIENCE LETTERS

Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults

(2008) F. Joseph McClernon et al.   NICOTINE & TOBACCO RESEARCH

Nicotine abstinence genotyping: assessing the impact on smoking cessation clinical trials

(2008) G R Uhl et al.   PHARMACOGENOMICS JOURNAL

Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies

(2008) Paul M. Johnson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Bupropion differentially alters the aversive, locomotor and rewarding properties of nicotine in CD-1 mice

(2008) A RAUHUT et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Nicotine withdrawal disrupts new contextual learning

(2008) George S. Portugal et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Neurobiology of nicotine dependence

(2008) A. Markou   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Age-dependent differences in nicotine reward and withdrawal in female mice

(2008) D. Kota et al.   PSYCHOPHARMACOLOGY

Effects of transdermal nicotine on episodic memory in non-smokers with and without schizophrenia

(2008) Lindsay E. Jubelt et al.   PSYCHOPHARMACOLOGY

A reliable method to study cue-, priming-, and stress-induced reinstatement of cocaine self-administration in mice

(2008) Guadalupe Soria et al.   PSYCHOPHARMACOLOGY

High Impulsivity Predicts the Switch to Compulsive Cocaine-Taking

(2008) D. Belin et al.   SCIENCE

“Higher order” addiction molecular genetics: Convergent data from genome-wide association in humans and mice

(2007) George R. Uhl et al.   BIOCHEMICAL PHARMACOLOGY

A Common Genetic Predisposition to Stress Sensitivity and Stress-Induced Nicotine Craving

(2007) Andras Bilkei-Gorzo et al.   BIOLOGICAL PSYCHIATRY

β2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning

(2007) George S. Portugal et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Nicotine place preference in a biased conditioned place preference design

(2007) Jennifer M. Brielmaier et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR