Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: known and novel aspects of the syndrome

Clinical heterogeneity and diagnostic delay of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome

(2011) Cinzia Mazza et al.   CLINICAL IMMUNOLOGY

IL-22 and TNF-α represent a key cytokine combination for epidermal integrity during infection withCandida albicans

(2011) Stefanie Eyerich et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: Clinical and pathogenetic implications

(2011) Kai Kisand et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17 signaling in host defense against Candida albicans

(2011) Sarah L. Gaffen et al.   IMMUNOLOGIC RESEARCH

Gain-of-function humanSTAT1mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

(2011) Luyan Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-7 Dysregulation and Loss of CD8+ T Cell Homeostasis in the Monogenic Human Disease Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

(2011) S. M. Laakso et al.   JOURNAL OF IMMUNOLOGY

Membrane-Bound IL-22 after De Novo Production in Tuberculosis and Anti-Mycobacterium tuberculosis Effector Function of IL-22+ CD4+ T Cells

(2011) G. Zeng et al.   JOURNAL OF IMMUNOLOGY

Post-splenectomy and hyposplenic states

(2011) Antonio Di Sabatino et al.   LANCET

New mechanism of oral immunity to mucosal candidiasis in hyper-IgE syndrome

(2011) H R Conti et al.   Mucosal Immunology

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

Measuring Autoantibodies against IL-17F and IL-22 in Autoimmune Polyendocrine Syndrome Type I by Radioligand Binding Assay Using Fusion Proteins

(2011) B. E. V. Oftedal et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Chronic Mucocutaneous Candidiasis in Humans with Inborn Errors of Interleukin-17 Immunity

(2011) A. Puel et al.   SCIENCE

Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

(2010) Pietro Luigi Poliani et al.   AMERICAN JOURNAL OF PATHOLOGY

Thymoma and paraneoplastic myasthenia gravis

(2010) A. Marx et al.   AUTOIMMUNITY

Renal Failure Associated with APECED and Terminal 4q Deletion: Evidence of Autoimmune Nephropathy

(2010) Mohammed Al-Owain et al.   Clinical & Developmental Immunology

AIRE gene mutations and autoantibodies to interferon omega in patients with chronic hypoparathyroidism without APECED

(2010) Sara Cervato et al.   CLINICAL ENDOCRINOLOGY

Aire and T cell development

(2010) Mark S Anderson et al.   CURRENT OPINION IN IMMUNOLOGY

Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model

(2010) Kerstin M. Ahlgren et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autoimmune Polyglandular Syndrome Type 1 in Russian Patients: Clinical Variants and Autoimmune Regulator Mutations

(2010) Elizaveta M. Orlova et al.   Hormone Research in Paediatrics

Autoimmune Polyendocrine Syndrome Type 1 in North-Western France: AIRE Gene Mutation Specificities and Severe Forms Needing Immunosuppressive Therapies

(2010) E. Proust-Lemoine et al.   Hormone Research in Paediatrics

Autoimmune Polyendocrine Syndromes: Clues to Type 1 Diabetes Pathogenesis

(2010) Eystein S. Husebye et al.   IMMUNITY

Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy

(2010) Wan-Fai Ng et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3+ precursors and impaired activated population

(2010) Sini M. Laakso et al.   JOURNAL OF AUTOIMMUNITY

21-Hydroxylase epitopes are targeted by CD8 T cells in autoimmune Addison’s disease

(2010) Diane Rottembourg et al.   JOURNAL OF AUTOIMMUNITY

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I

(2010) Anne Puel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines

(2010) Kai Kisand et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Autoimmune Regulator AIRE in Thymoma Biology: Autoimmunity and Beyond

(2010) Alexander Marx et al.   Journal of Thoracic Oncology

Cellular immunity and immunopathology in autoimmune Addison's disease

(2010) Eirik Bratland et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency

(2010) C. E. Teh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flow Cytometry Study of Blood Cell Subtypes Reflects Autoimmune and Inflammatory Processes in Autoimmune Polyendocrine Syndrome Type I

(2010) A. S. B. Wolff et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

Clinical and microstructural aberrations of enamel of deciduous and permanent teeth in patients with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy

(2009) Alenka Pavlič et al.   ARCHIVES OF ORAL BIOLOGY

γδ T cells develop independently of Aire

(2009) Heli Tuovinen et al.   CELLULAR IMMUNOLOGY

Pattern recognition receptor expression is not impaired in patients with chronic mucocutanous candidiasis with or without autoimmune polyendocrinopathy candidiasis ectodermal dystrophy

(2009) M. Hong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Novel sequence variation ofAIREand detection of interferon-ω antibodies in early infancy

(2009) Beáta Tóth et al.   CLINICAL ENDOCRINOLOGY

Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-α/β, IFN-γ, and IFN-λ in host defense

(2009) Shen-Ying Zhang et al.   IMMUNOLOGICAL REVIEWS

AIRE deficiency leads to impaired iNKT cell development

(2009) Emma Lindh et al.   JOURNAL OF AUTOIMMUNITY

T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency

(2009) Eirik Bratland et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Editorial: Functional Autoantibodies Cause Hypoparathyroidism

(2009) Eystein S. Husebye   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Activating Autoantibodies against the Calcium-Sensing Receptor Detected in Two Patients with Autoimmune Polyendocrine Syndrome Type 1

(2009) E. Helen Kemp et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I

(2009) E. S. Husebye et al.   JOURNAL OF INTERNAL MEDICINE

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

(2009) Francesca Chignola et al.   NUCLEIC ACIDS RESEARCH

Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen

(2009) M. Alimohammadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes

(2008) K. Kisand et al.   BLOOD

Hypothetical review: thymic aberrations and type-I interferons; attempts to deduce autoimmunizing mechanisms from unexpected clues in monogenic and paraneoplastic syndromes

(2008) A. Meager et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Impaired dendritic cell maturation and cytokine production in patients with chronic mucocutanous candidiasis with or without APECED

(2008) K. R. Ryan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I

(2008) Bergithe E. Oftedal et al.   CLINICAL IMMUNOLOGY

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

(2008) Tõnis Org et al.   EMBO REPORTS

Detection of a complete autoimmune regulator gene deletion and two additional novel mutations in a cohort of patients with atypical phenotypic variants of autoimmune polyglandular syndrome type 1

(2008) Katarina Trebušak Podkrajšek et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I

(2008) A S Bøe Wolff et al.   GENES AND IMMUNITY

Interferon-alpha controls IL-17 expression in vitro and in vivo

(2008) Alexander R. Moschen et al.   IMMUNOBIOLOGY

Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I

(2008) Antonella Meloni et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire

(2008) Maureen A. Su et al.   JOURNAL OF CLINICAL INVESTIGATION

Patients with Chronic Mucocutaneous Candidiasis Exhibit Reduced Production of Th17-Associated Cytokines IL-17 and IL-22

(2008) Kilian Eyerich et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Critical immunological pathways are downregulated in APECED patient dendritic cells

(2008) Nora Pöntynen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The myasthenia gravis thymus: A rare source of human autoantibody-secreting plasma cells for testing potential therapeutics

(2008) Marguerite E. Hill et al.   JOURNAL OF NEUROIMMUNOLOGY

Innate and adaptive immunity in patients with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy

(2008) R. Perniola et al.   MYCOSES

Autoimmune Polyendocrine Syndrome Type 1 and NALP5, a Parathyroid Autoantigen

(2008) Mohammad Alimohammadi et al.   NEW ENGLAND JOURNAL OF MEDICINE

AIRE regulates T-cell-independent B-cell responses through BAFF

(2008) E. Lindh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity

(2008) A. S. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE