Advancing drug discovery for schizophrenia

AKT Kinase Activity Is Required for Lithium to Modulate Mood-Related Behaviors in Mice

(2011) Jen Q Pan et al.   NEUROPSYCHOPHARMACOLOGY

Balancing histone methylation activities in psychiatric disorders

(2011) Cyril Jayakumar Peter et al.   TRENDS IN MOLECULAR MEDICINE

Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo

(2011) J A Allen et al.   Translational Psychiatry

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

The Psychiatric GWAS Consortium: Big Science Comes to Psychiatry

(2010) Patrick F. Sullivan   NEURON

Epigenetic GABAergic targets in schizophrenia and bipolar disorder

(2010) A. Guidotti et al.   NEUROPHARMACOLOGY

Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex

(2010) I. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral Olfactory System for Clinical and Basic Psychiatry: A Promising Entry Point to the Mystery of Brain Mechanism and Biomarker Identification in Schizophrenia

(2009) Akira Sawa et al.   AMERICAN JOURNAL OF PSYCHIATRY

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

(2009) Stephen J Huffaker et al.   NATURE MEDICINE

mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning

(2009) Jennifer E Ayala et al.   NEUROPSYCHOPHARMACOLOGY

Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation

(2009) Erbo Dong et al.   Epigenomics

Akt/GSK3 Signaling in the Action of Psychotropic Drugs

(2008) Jean-Martin Beaulieu et al.   Annual Review of Pharmacology and Toxicology

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

(2008) T. Walsh et al.   SCIENCE

Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling

(2008) Alessandro Guidotti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

(2008) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES