Is it time for in silico simulation of drug cardiac side effects?

Arrhythmic risk biomarkers for the assessment of drug cardiotoxicity: from experiments to computer simulations

(2012) A. Corrias et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk

(2011) Gary R. Mirams et al.   CARDIOVASCULAR RESEARCH

Novel Approaches to Assessing Cardiac Safety – Proceedings of a Workshop

(2011) Katherine Fletcher et al.   DRUG SAFETY

High-throughput functional curation of cellular electrophysiology models

(2011) Jonathan Cooper et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

An introduction to QT interval prolongation and non-clinical approaches to assessing and reducing risk

(2010) CE Pollard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Chaste: A test-driven approach to software development for biological modelling

(2009) Joe Pitt-Francis et al.   COMPUTER PHYSICS COMMUNICATIONS