Article
Virology
Soran Amin Hamalaw, Ali Hattem Bayati, Muhammed Babakir-Mina, Domenico Benvenuto, Silvia Fabris, Michele Guarino, Marta Giovanetti, Massimo Ciccozzi
Summary: Early detection and prompt response are crucial in preventing and controlling outbreaks. This study evaluates the performance of the Communicable Disease Surveillance System (CDSS) in the Kurdistan region of Iraq, finding deficiencies in surveillance guiding manuals, data analysis, epidemic preparedness, feedback, and standard guidelines. Strengthening the CDSS in this region requires continuous feedback, supervision, well-trained staff, and coordination between researchers and physicians.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Review
Cell Biology
Francesco Valentini, Giulia Rocchi, Umberto Vespasiani-Gentilucci, Michele Pier Luca Guarino, Annamaria Altomare, Simone Carotti
Summary: Fetal life and the first few months after birth are crucial periods for adaptation to environmental conditions and can have long-term metabolic consequences and impact on gut microbiota composition, thus affecting future health.
Review
Microbiology
Giulia Rocchi, Marta Giovanetti, Francesca Benedetti, Alessandra Borsetti, Giancarlo Ceccarelli, Davide Zella, Annamaria Altomare, Massimo Ciccozzi, Michele Pier Luca Guarino
Summary: The SARS-CoV-2 pandemic has caused an unprecedented global crisis. The virus primarily infects the lungs by binding to the ACE-2 cell receptor on the surface of alveolar epithelial cells. Interestingly, this receptor is also found in the epithelial cells of the intestinal tract. Recent data suggests that the gut microbiota may play a role in modulating inflammation. Gastrointestinal symptoms, including diarrhea, are often observed in infected individuals, and there is evidence that the virus can spread through fecal-oral transmission.
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Elena Imperia, Chiara Spiezia, Yeganeh Manon Khazrai, Michele Pier Luca Guarino
Summary: Inflammatory bowel diseases, including Chron's disease and ulcerative colitis, are chronic immune-mediated diseases of the intestinal tract. Dietary therapy has been shown to be crucial in managing symptoms and pathology of IBD, although there is currently no specific therapeutic diet. Further research is needed to determine the appropriate amount and type of fiber intake for IBD patients.
Review
Nutrition & Dietetics
Annamaria Altomare, Michele Fiore, Gabriele D'Ercole, Elena Imperia, Roberta Maria Nicolosi, Susanna Della Posta, Gabriella Pasqua, Michele Cicala, Laura De Gara, Sara Ramella, Michele Pier Luca Guarino
Summary: Radiotherapy-induced mucositis (RIOM) is a common side effect of anti-neoplastic treatments, affecting patients' quality of life and treatment response. Recent evidence suggests that natural compounds can potentially prevent and treat this damage without compromising treatment efficacy.
Review
Microbiology
Andras Bikov, Silvano Dragonieri, Balazs Csoma, Carmen Mazzuca, Panaiotis Finamore, Giulia Rocchi, Lorenza Putignani, Michele Guarino, Simone Scarlata
Summary: The bacteria in the human body, especially the gut microbiome, play an important role in respiratory diseases such as bronchial asthma, chronic obstructive pulmonary disease, and obstructive sleep apnea. This article summarizes the evidence and discusses the impact of altered gut microbiome on these diseases and their comorbidities, as well as the potential of manipulating the gut microbiome for therapeutic purposes.
Article
Gastroenterology & Hepatology
Alessandra Lo Presti, Federica Del Chierico, Annamaria Altomare, Francesca Zorzi, Giovanni Monteleone, Lorenza Putignani, Silvia Angeletti, Michele Cicala, Michele Pier Luca Guarino, Massimo Ciccozzi
Summary: This study investigated the phylogenetic dynamics of P. copri in patients with IBS, IBD, and healthy volunteers. Results showed longer genetic distances between IBD and healthy volunteers, as well as between IBD and IBS, indicating higher genetic variability in P. copri sequences within IBD. Different strains of P. copri were found in IBS patients, and a correlation between isolates and disease grading was observed. Understanding the phylogenetic characteristics of P. copri is important for better understanding the interactions between microbiota and the pathophysiology of IBD and IBS.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
(2023)
Article
Nutrition & Dietetics
Alessio Molfino, Sara Emerenziani, Giuseppe Tonini, Daniele Santini, Antonietta Gigante, Michele Pier Luca Guarino, Chiara Nuglio, Giovanni Imbimbo, Annalisa La Cesa, Michele Cicala, Maurizio Muscaritoli
Summary: This study evaluated the prevalence of anorexia, hypophagia, and cachexia in patients with gastrointestinal or lung cancer at time of diagnosis. The results showed that 68% of patients had cachexia, 57% had anorexia, and 48% had hypophagia. These conditions had negative impacts on patients' nutritional intake, indicating a need for early multimodal strategies to improve food intake.
FRONTIERS IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Vittoria Terrigno, Florencia Carbone, Jan Tack, Michele Cicala, Michele Pier Luca Guarino
Summary: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. The exact cause of IBS is not fully understood, but it is believed to involve a combination of factors such as abnormal gut motility, inflammation, increased intestinal permeability, and sensitivity. Diet and gut microbiota have also been identified as important contributors to IBS. This review examines the effects of dietary components, functional foods, prebiotics, probiotics, and symbiotics on symptoms and gut microbiota in individuals with IBS-C.
Meeting Abstract
Gastroenterology & Hepatology
A. Altomare, G. Rocchi, F. Zorzi, F. Del Chierico, A. Lo Presti, S. Emerenziani, C. Nuglio, L. Pica, M. Ciccozzi, L. Putignani, M. Cicala, M. P. L. Guarino
DIGESTIVE AND LIVER DISEASE
(2022)
