Ratiometric Activatable Cell-Penetrating Peptides Label Pancreatic Cancer, Enabling Fluorescence-Guided Surgery, Which Reduces Metastases and Recurrence in Orthotopic Mouse Models

Fluorescence-guided Surgery with a Fluorophore-conjugated Antibody to Carcinoembryonic Antigen (CEA), that Highlights the Tumor, Improves Surgical Resection and Increases Survival in Orthotopic Mouse Models of Human Pancreatic Cancer

(2014) Cristina A. Metildi et al.   ANNALS OF SURGICAL ONCOLOGY

Successful Fluorescence-Guided Surgery on Human Colon Cancer Patient-Derived Orthotopic Xenograft Mouse Models Using a Fluorophore-Conjugated Anti-CEA Antibody and a Portable Imaging System

(2014) Yukihiko Hiroshima et al.   Journal of Laparoendoscopic & Advanced Surgical Techniques

Fluorescently labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model

(2013) Cristina A. Metildi et al.   JOURNAL OF SURGICAL ONCOLOGY

Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides

(2012) E. N. Savariar et al.   CANCER RESEARCH

An LED Light Source and Novel Fluorophore Combinations Improve Fluorescence Laparoscopic Detection of Metastatic Pancreatic Cancer in Orthotopic Mouse Models

(2012) Cristina A. Metildi et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection

(2011) Hiroyuki Kishimoto et al.   CELL CYCLE

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Glowing Tumors Make for Better Detection and Resection

(2011) M. Bouvet et al.   Science Translational Medicine

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

(2010) Q. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The FLARE™ Intraoperative Near-Infrared Fluorescence Imaging System: A First-in-Human Clinical Trial in Breast Cancer Sentinel Lymph Node Mapping

(2009) Susan L. Troyan et al.   ANNALS OF SURGICAL ONCOLOGY

Real-time identification of liver cancers by using indocyanine green fluorescent imaging

(2009) Takeaki Ishizawa et al.   CANCER

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

(2009) Emilia S. Olson et al.   Integrative Biology

Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides

(2009) Todd A. Aguilera et al.   Integrative Biology

Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses

(2009) H. Kishimoto et al.   MOLECULAR CANCER THERAPEUTICS

In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation

(2009) H. Kishimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fluorophore-conjugated anti-CEA Antibody for the Intraoperative Imaging of Pancreatic and Colorectal Cancer

(2008) Sharmeela Kaushal et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Imaging of Primary and Metastatic Pancreatic Cancer Using a Fluorophore-Conjugated Anti-CA19-9 Antibody for Surgical Navigation

(2008) Michele McElroy et al.   WORLD JOURNAL OF SURGERY