Article
Oncology
M. Degiuli, R. Reddavid, M. Tomatis, A. Ponti, M. Morino, M. Sasako
Summary: This study compared the effects of D1 and D2 gastrectomy on gastric cancer patients, showing that D2 surgery can significantly improve survival and reduce gastric cancer-related mortality in patients with advanced disease and lymph node metastasis. D1 surgery may be more effective in older patients and early-stage disease.
EUROPEAN JOURNAL OF CANCER
(2021)
Review
Medicine, Research & Experimental
Yongpu Yang, Yuyan Chen, Yilin Hu, Ying Feng, Qinsheng Mao, Wanjiang Xue
Summary: This meta-analysis compares the surgical and survival outcomes of laparoscopic total gastrectomy with D2 lymphadenectomy (LTGD2) and open total gastrectomy with D2 lymphadenectomy (OTGD2) for gastric cancer. The results show that LTGD2 has advantages in terms of less blood loss, lower postoperative complication rates, faster postoperative recovery, and shorter hospital stays compared to OTGD2, but there is no significant difference in the number of lymph nodes dissected and 5-year survival rates.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2022)
Review
Surgery
Sailiang Liu, Laiyuan Li, Haojie Sun, Bojie Chen, Minhao Yu, Ming Zhong
Summary: This meta-analysis aimed to compare the outcomes of D3 and D2 lymphadenectomy in right hemicolectomy for right colon cancer. The results showed that D3 lymphadenectomy was superior to D2 lymphadenectomy in terms of blood loss, harvested lymph nodes, 3-year overall survival, 5-year overall survival, and 5-year disease-free survival. Further randomized controlled trials are needed for stronger evidence.
SURGICAL INNOVATION
(2022)
Review
Oncology
Ognjen Barcot, Matija Boric, Marija Cavar, Goran Poropat, Livia Puljak
Summary: The study found that measuring abdominal drain amylase level (d-AMY) on postoperative day 1 can accurately predict the development of postoperative pancreatic fistula (POPF) after gastric surgery, with high sensitivity and specificity.
Article
Medicine, General & Internal
Xiangyu Meng, Lu Wang, Guangcong Liu, Jun Zhang, Yue Wang, Dong Yang, Guoliang Zheng, Tao Zhang, Zhichao Zheng, Yan Zhao
Summary: Based on Chinese data, this study found that D2 radical gastrectomy plus complete mesogastrium excision (CME) provides better surgical outcomes and lower risk of complications compared to D2 radical gastrectomy alone.
CHINESE MEDICAL JOURNAL
(2022)
Review
Oncology
Bo Dong, Anyuan Zhang, Yuqiang Zhang, Wei Ye, Lan Liao, Zonglin Li
Summary: This study evaluated the efficacy of indocyanine green (ICG) fluorescence imaging-guided lymphadenectomy in radical gastrectomy for gastric cancer. The pooled analysis showed that the use of ICG increased the number of retrieved lymph nodes and reduced intraoperative blood loss. There was no significant impact on operative time and overall complications. In terms of oncological outcomes, ICG imaging decreased the overall recurrence rate but did not significantly improve the 2-year overall survival rate.
FRONTIERS IN ONCOLOGY
(2022)
Article
Surgery
Casey J. Allen, David T. Pointer, Alisa N. Blumenthaler, Rutika J. Mehta, Sarah E. Hoffe, Bruce D. Minsky, Grace L. Smith, Mariela Blum, Paul F. Mansfield, Naruhiko Ikoma, Prajnan Das, Jaffer Ajani, Sean P. Dineen, Jason B. Fleming, Brian D. Badgwell, Jose M. Pimiento
Summary: The study results indicated that in patients with gastric adenocarcinoma, those who received neoadjuvant chemotherapy plus chemoradiation (CRT) had higher rates of completed perioperative therapy, higher rates of complete pathologic response, lower pathologic stage, and improved survival.
Article
Oncology
Andre Roncon Dias, Amir Zeide Charruf, Marcus Fernando Kodama Pertille Ramos, Ulysses Ribeiro, Bruno Zilberstein, Ivan Cecconello
Summary: D2 lymphadenectomy for gastric cancer is technically demanding and requires clearance of the lymph node stations along the main arteries that irrigate the stomach and the liver. Surgeons must be aware of anatomical variations in vessel irrigation to safely perform the procedure and avoid complications.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Medicine, General & Internal
Lucian Mocan
Summary: Gastric cancer is the fifth most common cancer worldwide, with surgery being the only curative treatment. Early detection and screening combined with neoadjuvant therapy can reduce the incidence of gastric cancer, but patients are often diagnosed at an advanced stage.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Itamoto Kota, Hikage Makoto, Kamiya Satoshi, Tanizawa Yutaka, Bando Etsuro, Terashima Masanori
Summary: D1+ gastrectomy may be oncologically feasible for patients with cT1N1, cT2N0-1, or cT3N0 stage gastric cancer, with similar outcomes compared to D2 gastrectomy.
Review
Oncology
Bas A. Uijterwijk, Kongyuan Wei, Meidai Kasai, Benedetto Ielpo, Jony van Hilst, Palanivelu Chinnusamy, Daniel H. L. Lemmers, Fernando Burdio, Palanisamy Senthilnathan, Marc G. Besselink, Mohammed Abu Hilal, Renyi Qin
Summary: This study compared the oncological and surgical outcomes of minimally invasive pancreatoduodenectomy (MIPD) and open pancreatoduodenectomy (OPD) in patients with resectable pancreatic ductal adenocarcinoma (PDAC). The results showed that MIPD was non-inferior to OPD in terms of radicality, lymph node yield, major complications, and 90-day mortality. MIPD also had advantages in terms of blood loss, hospital stay, and operation time. These findings suggest that MIPD is a viable alternative to traditional surgery.
Article
Oncology
Elizabeth Jacob, Levi Smucker, Ryan Crouse, Ayana Allard-Picou
Summary: This case presents a rare instance of isolated extremity metastasis of gastric adenocarcinoma following R0 resection of the primary tumor and negative nodal disease, suggesting hematogenous spread. It underscores the importance of understanding the biology, workup, and management of gastric cancer for improved treatment outcomes.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Giulio Illuminati, Antonio D'Urso, Enrico Fiori, Saverio Cerasari, Priscilla Nardi, Alfonso Lapergola, Rocco Pasqua, Salvatore Sorrenti, Daniele Pironi, Augusto Lauro, Vito D'Andrea
Summary: The aim of this retrospective study was to compare the outcomes of laparoscopy-assisted total gastrectomy (LATG) and open total gastrectomy (OTG) for advanced gastric cancer. The study found that OTG had comparable results to LATG in terms of postoperative mortality, morbidity, overall survival (OS), disease-free survival (DFS), number of retrieved lymph nodes, operating time, intraoperative blood loss, postoperative length of stay (LOS), and incidence of local recurrence.
UPDATES IN SURGERY
(2023)
Review
Surgery
Shenghan Lou, Xin Yin, Yufei Wang, Yao Zhang, Yingwei Xue
Summary: This study evaluated the benefits and risks of laparoscopic gastrectomy (LG) compared to open gastrectomy (OG) for the treatment of gastric cancer. The results showed that LG had advantages such as less blood loss, fewer postoperative complications, and faster recovery, but had disadvantages such as shorter proximal resection margin length, longer operation time, and fewer retrieved lymph nodes compared to OG. LG can be an alternative approach to OG for experienced surgeons, and patients with lower BMI and older age may benefit most.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Multidisciplinary Sciences
Greg Marchand, Ahmed Taher Masoud, Ahmed Abdelsattar, Alexa King, Hollie Ulibarri, Julia Parise, Amanda Arroyo, Catherine Coriell, Sydnee Goetz, Carmen Moir, Atley Moberly, Malini Govindan
Summary: Recent evidence suggests that laparoscopic radical hysterectomy (LRH) and robot-assisted radical hysterectomy (RRH) open techniques (ORH) are associated with an increase in recurrence and a decrease in overall survival in patients with cervical cancer. This study aimed to reassess the outcomes of LRH compared to ORH, excluding RRH. A systematic review was conducted, and 60 studies met the eligibility criteria. The findings indicate that LRH is associated with a shorter hospital stay, less blood loss, and a lower complication rate compared to ORH, while ORH is superior in terms of operating time and the number of resected lymph nodes.
SCIENTIFIC REPORTS
(2023)
Editorial Material
Oncology
Matthew E. B. Dixon, Niraj J. Gusani
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
Elizabeth J. Olecki, Kelly A. Stahl, Madeline B. Torres, June S. Peng, Matthew Dixon, Chan Shen, Niraj J. Gusani
Summary: This study examined the benefit of adjuvant chemotherapy (AT) for patients with pancreatic adenocarcinoma after completion of neoadjuvant chemotherapy (NT) and surgical resection. The results showed a significant survival benefit for subgroups with low-risk pathologic features, suggesting the addition of AT after NT may be beneficial for these patients.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Editorial Material
Oncology
Elizabeth J. Olecki, Kelly A. Stahl, Madeline B. Torres, June S. Peng, Matthew Dixon, Chan Shen, Niraj J. Gusani
ANNALS OF SURGICAL ONCOLOGY
(2021)
Letter
Gastroenterology & Hepatology
Courtney Lester, Leonard Walsh, Kayla M. Hartz, Abraham Mathew, John M. Levenick, Brandy D. Headlee, Heather D. Heisey, James H. Birkholz, Matthew Dixon, Jennifer L. Maranki, Niraj J. Gusani, Charles E. Dye, Matthew T. Moyer
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
William Wong, Rolfy A. Perez Holguin, Elizabeth J. Olecki, Kelly A. Stahl, Matthew Dixon, June Peng, Arvind Dasari, Chan Shen
Summary: This study evaluated the national trends in minimally invasive surgery (MIS) for small bowel neuroendocrine tumors (SBNETs) and its association with lymph node (LN) yield. The study found that the utilization of MIS has increased, especially in higher volume centers. MIS patients had a greater number of LN harvested and shorter length of stay compared to open surgery patients.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Oncology
Madeline B. Torres, Matthew E. B. Dixon, Niraj J. Gusani
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA
(2022)
Review
Gastroenterology & Hepatology
Elizabeth J. Olecki, Joanna Swinarska, Rolfy A. Perez Holguin, Kelly A. Stahl, William G. Wong, June S. Peng, Matthew E. B. Dixon
Summary: Background: Jaundice in periampullary neoplasms is often treated with biliary stenting. Level 1 data showed increased complications after pancreaticoduodenectomy in patients with stents. This study analyzed US patient data and found that preoperative biliary stenting is still common, but the non-stent group had lower overall complications and postoperative infections. There was no significant difference in mortality and pancreatic fistula rate between groups. Conclusion: Despite the increased risk of complications, biliary stenting will likely remain common practice due to the trend of increased utilization of neoadjuvant chemotherapy.
Article
Oncology
William G. Wong, Rolfy A. Perez Holguin, Anna Y. Tarren, Chan Shen, Charles Vining, June S. Peng, Matthew E. Dixon
Summary: This study compares the predictive ability of different scoring systems for posthepatectomy liver failure (PHLF) and 30-day mortality. The results show that the ALBI score is more accurate in predicting severe PHLF and 30-day mortality than the MELD-Na and PALBI scores.
JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Rolfy A. Perez Holguin, Elizabeth J. Olecki, Kelly A. Stahl, William G. Wong, Charles C. Vining, Matthew E. B. Dixon, June S. Peng
Summary: This study aimed to determine the optimal treatment for cT2N0 esophageal and gastroesophageal junction adenocarcinoma. The results showed that adjuvant therapy was associated with improved survival compared to neoadjuvant therapy and surgery-alone. Selective use of adjuvant therapy for patients who are upstaged pathologically or have high-risk features can lead to better outcomes.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Surgery
Rolfy A. Perez Holguin, Kelly A. Stahl, Brandon S. Hendriksen, William G. Wong, Elizabeth J. Olecki, Charles C. Vining, Matthew E. Dixon, June S. Peng, Chan Shen
Summary: This study found that robotic-assisted gastrectomy had a lower conversion rate compared to laparoscopic gastrectomy. Conversion to open surgery was associated with longer hospital stay and higher rates of positive surgical margins.
JOURNAL OF SURGICAL RESEARCH
(2022)
Meeting Abstract
Surgery
William G. Wong, Rolfy A. Perez Holguin, Elizabeth Olecki, Charles C. Vining, Matthew E. Dixon, June S. Peng
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Meeting Abstract
Surgery
Elizabeth J. Olecki, Rolfy Perez Holguin, William G. Wong, Joanna Swinarska, Charles C. Vining, June Peng, Matthew E. B. Dixon
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Meeting Abstract
Surgery
William G. Wong, Rolfy A. Perez Holguin, Jonatham Pham, Colette R. Pameijer, Matthew E. Dixon, June S. Peng, Charles C. Vining
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Meeting Abstract
Gastroenterology & Hepatology
William G. Wong, Rolfy A. Perez Holguin, Elizabeth J. Olecki, Kelly A. Stahl, Matthew E. Dixon, June S. Peng, Arvind Dasari, Chan Shen
Meeting Abstract
Oncology
Joanna T. Swinarska, Charles Vining, Matthew Dixon, June Peng
ANNALS OF SURGICAL ONCOLOGY
(2022)