Article
Psychiatry
Dan J. Stein, Steven J. Shoptaw, Daniel V. Vigo, Crick Lund, Pim Cuijpers, Jason Bantjes, Norman Sartorius, Mario Maj
Summary: Psychiatry has been characterized by different models and approaches to mental disorder. The focus of debate in recent decades has been on psychiatric nosology and the need for new paradigms. Despite the development of evidence-based treatments, there is still a treatment and research-practice gap in mental health. Novel perspectives such as clinical neuroscience and personalized pharmacotherapy, statistical approaches, community mental health care, digital therapies, and global mental health approaches have the potential to impact psychiatric practice and research.
Article
Oncology
Michele Maddalo, Lorenzo Bertolotti, Aldo Mazzilli, Andrea Giovanni Maria Flore, Rocco Perotta, Francesco Pagnini, Francesco Ziglioli, Umberto Maestroni, Chiara Martini, Damiano Caruso, Caterina Ghetti, Massimo De Filippo
Summary: Using a machine learning model based on radiomic features, this study developed a pipeline to distinguish between malignant and benign small renal masses. The model achieved good performance in accurately classifying renal cell carcinomas and benign renal tumors.
Article
Environmental Sciences
Shuyao Wu, Laibao Liu, Delong Li, Wentao Zhang, Kaidu Liu, Jiashu Shen, Linbo Zhang
Summary: This study evaluates the distribution and changes of global deserts by combining climate classification maps and long-term observational data. The results show that approximately 7.53% of global land is covered by deserts, and only about 16.03% of these deserts are expanding. The study also identifies vegetation cover diversity as the strongest predictor for both hot and cold desert expansion.
LAND DEGRADATION & DEVELOPMENT
(2023)
Article
Acoustics
Austin Kwong, Ana Mitchell, Danielle Wang, John P. McGahan
Summary: This study retrospectively reviewed consecutive renal ultrasound examinations and found that most echogenic renal masses were benign angiomyolipomas (AMLs), with a smaller proportion being renal cell carcinomas (RCCs). The majority of masses smaller than or equal to 2 cm were benign, while further evaluation was necessary for masses larger than 2 cm.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Review
Anesthesiology
Jeanna D. Blitz
Summary: This review aims to provide a conceptual framework for preoperative evaluation and to highlight the clinical evidence available to support perioperative decision-making.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jose Pablo Pedraza-Sanchez, Reyes Chaves-Marcos, Javier Mazuecos-Quiros, alvaro Luis Bisono-Castillo, Ignacio Osman-Garcia, Carlos Miguel Gutierrez-Marin, Rafael Antonio Medina Lopez, Alvaro Juarez Soto
Summary: This study compared the efficacy, safety, and oncological outcomes of percutaneous radiofrequency ablation (PRFA) and partial nephrectomy (PN) for small renal masses (SRMs). The results showed that PRFA is non-inferior to PN in terms of oncological outcomes and safety, particularly for high-risk patients.
EUROPEAN RADIOLOGY
(2023)
Article
Urology & Nephrology
Teele Kuusk, Joana B. Neves, Maxine Tran, Axel Bex
Summary: This study conducted a narrative review on the applications of radiomics in characterizing small renal masses, focusing on methods to accurately differentiate between benign and malignant renal masses, especially different subtypes of renal cell carcinoma and other specific types. It found that radiomics has the potential to improve non-invasive diagnostic accuracy and predict the behavior of small renal masses, but further prospective validation studies are needed for better management algorithms.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Environmental Sciences
Carlos A. Novaes, Rui Cunha Marques
Summary: Stormwater systems in most cities are crucial but often overlooked infrastructure, relying on weak institutional and organizational structures. Solving the issues associated with these systems requires more than just technological solutions, but also a paradigm shift towards a new socio-institutional mentality that addresses new demands.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Agriculture, Dairy & Animal Science
Patricia V. Turner, Kathryn Bayne
Summary: Continued evolution of research animal care is crucial for upholding the principles of replacement, reduction, and refinement. Animals' feelings are fundamental to their behavior and welfare, and an updated behavioral management program that considers their needs and desired outcomes is proposed. This approach not only enhances animal welfare but also improves the scientific quality of research. The expansion of these programs to include all research species is necessary to reduce stress, encourage natural behaviors, and generate reliable scientific data. An umbrella-based model for research animal behavioral management programs is described, along with the importance of regular welfare assessments to ensure the program's effectiveness and identify areas for improvement.
Article
Urology & Nephrology
Jessica C. Dai, Tara Nikonow Morgan, Devan Moody, Joseph McLaughlin, Jeffrey A. Cadeddu
Summary: The incidence of localized renal cell carcinoma has increased in recent decades due to greater use of imaging, but treatment has shifted towards less invasive, nephron-sparing approaches like radiofrequency ablation (RFA). RFA offers the advantages of being minimally invasive and highly nephron sparing, with the added benefits of reduced blood loss and complication rates.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Oncology
Genevieve Charbonneau, Catherine Hudon, Luke T. Lavallee, Wassim Kassouf, Isabelle Gaboury, Paul Toren, Felix Couture, Veronique Foley, Amelie Tetu, Patrick O. Richard
Summary: Patients' perceptions of active surveillance for SRMs vary among individuals, with their physician's recommendation being one of the most important influencing factors. Developing more patient-oriented information tools is necessary to educate patients, reduce physician influence on decision-making, and ensure that patients' decisions reflect their own values and preferences.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Urology & Nephrology
Jessica C. Dai, Tara N. Morgan, Ryan L. Steinberg, Brett A. Johnson, Alaina Garbens, Jeffrey A. Cadeddu
Summary: This study reported the 5-year oncologic outcomes of percutaneous IRE for small renal masses, showing that IRE has low morbidity but suboptimal intermediate-term oncologic outcomes compared with conventional thermal ablation techniques for small low-complexity tumors and should be restricted to select cases.
JOURNAL OF ENDOUROLOGY
(2021)
Article
Urology & Nephrology
Sandra Seo Young Kim, Rodney Breau, Ranjeeta Mallick, Anil Kapoor, Antonio Finelli, Frederic Pouliot, Simon Tanguay, Adrian Fairey, Bimal Bhindi, Luke Lavallee, Alan So, Ricardo Rendon
Summary: The study found a strong correlation between ultrasound and cross-sectional imaging with pathological renal mass sizes, especially for small renal masses. There was high agreement between ultrasound and cross-sectional imaging in 75% of patients at baseline imaging. Correlation between ultrasound and CT/MRI for small renal masses was higher in patients with lower body mass index.
Review
Chemistry, Physical
Thomas J. P. Hersbach, Marc T. M. Koper
Summary: Cathodic corrosion, an enigmatic electrochemical process discovered in the late 1800s, has attracted increased attention in the past decade. Recent advances have led to new insights into the effects and possible reaction intermediates of cathodic corrosion, as well as applications in nanoparticle synthesis and electrocatalyst modification.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Review
Medicine, General & Internal
Lorenzo Bertolotti, Maria Vittoria Bazzocchi, Enrico Iemma, Francesco Pagnini, Francesco Ziglioli, Umberto Maestroni, Annalisa Patera, Matteo Pio Natale, Chiara Martini, Massimo De Filippo
Summary: Over the past two decades, the detection rate of small renal masses has increased, leading to the preference for nephron-sparing treatments. Thermal ablation, including radiofrequency ablation, cryoablation, and microwave ablation, has gained popularity as a minimally invasive alternative with good clinical outcomes and low recurrence rates. These techniques require imaging studies, such as ultrasound and CT, to assess lesions and plan procedures. This review aims to compare different ablative modalities and imaging guides, providing guidance for interventional radiologists in selecting the best treatment option.
Article
Surgery
Daniel Pucheril, Sean A. Fletcher, Xi Chen, David F. Friedlander, Alexander P. Cole, Marieke J. Krimphove, Adam C. Fields, Nelya Melnitchouk, Adam S. Kibel, Prokar Dasgupta, Quoc-Dien Trinh
Summary: This retrospective insurance-based analysis showed that robotic surgery was associated with fewer missed days from work compared to open surgery for major procedures such as radical prostatectomy, hysterectomy/myomectomy, and partial colectomy. This information can help stakeholders better understand the indirect benefits of robotic surgery in relation to its cost.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Pamela W. Lu, Rebecca E. Scully, Adam C. Fields, Vanessa M. Welten, Stuart R. Lipsitz, Quoc-Dien Trinh, Adil Haider, Joel S. Weissman, Karen M. Freund, Nelya Melnitchouk
Summary: Racial disparities exist in patients with rectal cancer in terms of treatment and survival outcomes. Patients treated at minority-serving hospitals have lower odds of receiving standard of care treatment for locally advanced rectal adenocarcinoma, with Black patients experiencing higher mortality risk compared to White patients.
JOURNAL OF GASTROINTESTINAL SURGERY
(2021)
Article
Oncology
Marco Bandini, Jeffrey S. Ross, Daniele Raggi, Andrea Gallina, Maurizio Colecchia, Roberta Luciano, Patrizia Giannatempo, Elena Fare, Filippo Pederzoli, Marco Bianchi, Renzo Colombo, Giorgio Gandaglia, Nicola Fossati, Laura Marandino, Umberto Capitanio, Federico Deho', Siraj M. Ali, Russell Madison, Jon H. Chung, Andrea Salonia, Alberto Briganti, Francesco Montorsi, Andrea Necchi
Summary: The study presents a composite biomarker-based pT0N0 probability calculator that reveals the complex interplay between tumor mutational burden (TMB), programmed cell-death-ligand-1 (PD-L1)-combined positive score (CPS), and clinical T stage. The calculator showed a high predictive value with a C index of 0.77, and decision-curve analysis demonstrated a higher net benefit compared to the treat-all option within clinically meaningful threshold probabilities.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Oncology
Junaid Nabi, Karl H. Tully, Alexander P. Cole, Maya Marchese, Eugene B. Cone, Nelya Melnitchouk, Adam S. Kibel, Quoc-Dien Trinh
Summary: The study found that underinsured, Medicare-insured, and Medicaid-insured patients are less likely to receive surgical care at high-volume hospitals. For patients with colorectal cancer, the effect of insurance coverage differed by study period, and improved since 2011.
Article
Urology & Nephrology
David F. Friedlander, Aaron Brant, Timothy D. McClure, Joseph Del Pizzo, Molly A. Nowels, Quoc-Dien Trinh, Art Sedrakyan, Bilal Chughtai
Summary: This study analyzed data from the New York State database on nearly 220,000 patients who underwent ureterorenoscopy or shockwave lithotripsy between 2000 and 2016, finding that patients undergoing shockwave lithotripsy had lower 30-day complication rates but higher odds of treatment failure at 90 and 180 days.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Surgery
Austin Haag, Junaid Nabi, Peter Herzog, Nicollette K. Kwon, Maya Marchese, Adam Fields, Jolene Wun, David F. Friedlander, Eugene B. Cone, Quoc-Dien Trinh
Summary: This study assessed the perioperative outcomes and costs of colorectal surgeries for TRICARE military beneficiaries, finding that direct care was associated with higher readmissions, similar overall complications, and higher costs compared to purchased care. Interestingly, higher volume in the direct-care setting did not translate to fewer complications, challenging common assumptions about volume and quality in healthcare.
Article
Respiratory System
Stephen W. Reese, Eugene Cone, Maya Marchese, Brenda Garcia, Wesley Chou, Asha Ayub, Kerry Kilbridge, Gerald Weinhouse, Quoc-Dien Trinh
Summary: The study identified associations between immune checkpoint inhibitors and pulmonary toxicities, including pneumonitis, interstitial lung disease, pulmonary embolism, and respiratory failure. The research also found other associations with immune checkpoint inhibitors, although not consistently across all agents. Many of these immune-related adverse drug reactions were severe and contributed to a significant source of mortality in reported cases.
Article
Oncology
Hari S. Iyer, Scarlett L. Gomez, Jarvis T. Chen, Quoc-Dien Trinh, Timothy R. Rebbeck
Summary: The study found that Black-White disparities in prostate cancer mortality decreased over the study period in Massachusetts and Pennsylvania, while neighborhood socioeconomic status mortality disparities trends either stagnated or increased, calling for further attention and action.
Article
Oncology
Bhav Jain, Kenrick Ng, Patricia Mae G. Santos, Kekoa Taparra, Vinayak Muralidhar, Brandon A. Mahal, Neha Vapiwala, Quoc-Dien Trinh, Paul L. Nguyen, Edward Christopher Dee
Summary: The study identified differences in localized prostate cancer risk group at presentation and disparities in treatment patterns for different Asian American, Native Hawaiian, and Pacific Islander subgroups. Further research is needed to assess and address barriers to prostate cancer care.
JCO ONCOLOGY PRACTICE
(2022)
Review
Health Care Sciences & Services
Logan G. Briggs, Muhieddine Labban, Khalid Alkhatib, David-Dan Nguyen, Alexander P. Cole, Quoc-Dien Trinh
Summary: Digital health technology plays a crucial role in cancer care, promoting personalized medicine and enhancing the quality and accessibility of healthcare services. Physicians utilize various digital health technologies such as smartphone apps, wearable devices, and web-based communication platforms to improve cancer screening, patient education, symptom monitoring, and other aspects of cancer care.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2022)
Article
Oncology
Zhiyu Qian, Khalid Al Khatib, Xi Chen, Sanvi Belani, Muhieddine Labban, Stuart Lipsitz, Alexander P. Cole, Hari S. Iyer, Quoc-Dien Trinh
Summary: PSA screening among younger black and white men has steadily decreased since 2012, but the decrease has been more rapid among black men compared to white men.
JNCI CANCER SPECTRUM
(2023)
Article
Oncology
Nico C. Grossmann, Francesco Soria, Tristan Juvet, Aaron M. Potretzke, Hooman Djaladat, Alireza Ghoreifi, Eiji Kikuchi, Andrea Mari, Zine-Eddine Khene, Kazutoshi Fujita, Jay D. Raman, Alberto Breda, Matteo Fontana, John P. Sfakianos, John L. Pfail, Ekaterina Laukhtina, Pawel Rajwa, Maximillian Pallauf, Cedric Poyet, Giovanni E. Cacciamani, Thomas van Doeveren, Joost L. Boormans, Alessandro Antonelli, Marcus Jamil, Firas Abdollah, Guillaume Ploussard, Axel Heidenreich, Enno Storz, Siamak Daneshmand, Stephen A. Boorjian, Morgan Roupret, Michael Rink, Shahrokh F. Shariat, Benjamin Pradere
Summary: The study compared perioperative and oncologic outcomes among patients who underwent open, laparoscopic, and robotic RNU for non-metastatic upper urinary tract urothelial carcinoma. The results showed worse bladder recurrence-free survival in patients who had laparoscopic and robotic RNU compared to open RNU. However, recurrence-free, cancer-specific, and overall survival were similar between the three surgical approaches. Laparoscopic and robotic RNU were associated with shorter hospital stay and fewer major postoperative complications. Further research is needed to investigate the factors responsible for the inferior bladder recurrence-free survival in patients treated with minimally invasive techniques.
Article
Urology & Nephrology
Edoardo Beatrici, Muhieddine Labban, Benjamin V. Stone, Dejan K. Filipas, Leonardo O. Reis, Giovanni Lughezzani, Nicolo M. Buffi, Adam S. Kibel, Alexander P. Cole, Quoc-Dien Trinh
Summary: The use of expectant management for low-risk prostate cancer has significantly increased over the past decade, likely due to growing awareness of the harms of overtreatment.
Article
Oncology
Dejan K. Filipas, Edoardo Beatrici, Jose Nolazco, Zhiyu Qian, Phillip Marks, Muhieddine Labban, Benjamin Stone, Phillip M. Pierorazio, Stuart R. Lipsitz, Quoc-Dien Trinh, Steven L. Chang, Alexander P. Cole
Summary: The use of nonoperative management for small renal masses has increased over the past decade. Observational management is more frequently used among Black patients. Possible reasons include race-based differences in physicians' risk assessments and resource allocation.
JNCI CANCER SPECTRUM
(2023)
Article
Urology & Nephrology
Muhieddine Labban, Nicola Frego, Zhiyu Qian, David-Dan Nguyen, Chang-Rong Chen, Brittany D. Berk, Stuart R. Lipsitz, Naeem Bhojani, Martin Kathrins, Quoc-Dien Trinh
Summary: The 5-item Frailty Index (5i-FI) is a useful predictor of surgical complications in endoscopic surgery for benign prostatic obstruction (BPO). After adjusting for selection bias, laser enucleation of the prostate (LEP) and photoselective vaporization of the prostate (PVP) are associated with lower rates of complications compared to transurethral resection of the prostate (TURP). However, frail patients are less likely to undergo PVP and LEP. Preoperative frailty assessment can improve risk stratification in BPO surgery.
WORLD JOURNAL OF UROLOGY
(2022)