ROS1 Receptor Tyrosine Kinase, a Druggable Target, is Frequently Overexpressed in Non-Small Cell Lung Carcinomas Via Genetic and Epigenetic Mechanisms

ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

(2012) Kristin Bergethon et al.   JOURNAL OF CLINICAL ONCOLOGY

Survey of Tyrosine Kinase Signaling Reveals ROS Kinase Fusions in Human Cholangiocarcinoma

(2011) Ting-Lei Gu et al.   PLoS One

PIK3CA Mutations May Be Discordant between Primary and Corresponding Metastatic Disease in Breast Cancer

(2010) J. Dupont Jensen et al.   CLINICAL CANCER RESEARCH

Design, synthesis and biological evaluation of new potent and highly selective ROS1-tyrosine kinase inhibitor

(2009) Byung Sun Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, screening, and molecular modeling study of a new series of ROS1 receptor tyrosine kinase inhibitors

(2009) Ibrahim M. El-Deeb et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Epigenetic Regulation of c-ROS Receptor Tyrosine Kinase Expression in Malignant Gliomas

(2009) H. J. Jun et al.   CANCER RESEARCH

Genetic disparity between primary tumours, disseminated tumour cells, and manifest metastasis

(2009) Nikolas H. Stoecklein et al.   INTERNATIONAL JOURNAL OF CANCER

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE