Article
Radiology, Nuclear Medicine & Medical Imaging
Noam Nissan, Efi Efraim Moss Massasa, Ethan Bauer, Osnat Halshtok-Neiman, Anat Shalmon, Michael Gotlieb, Renata Faermann, David Samoocha, Yael Yagil, Tomer Ziv-Baran, Debbie Anaby, Miri Sklair-Levy
Summary: This study aimed to test the diagnostic performance of breast dynamic contrast-enhanced (DCE) MRI during lactation. The results showed that the readers achieved a high diagnostic accuracy in the MIP-DCE images, but with some false-positive interpretations. In addition, the BPE grades were significantly higher in the healthy controls compared to the PABC cohort, while the CNR decreased gradually in the four post-contrast images.
EUROPEAN RADIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Francisco Javier Sanchez, Esther Pueyo, Emiliano Raul Diez
Summary: Postoperative atrial fibrillation (POAF) is a complication of cardiovascular surgeries that increases the risk of embolic stroke, prolonged hospital stay, and cardiovascular mortality. While many pathophysiological mechanisms are known, predicting POAF remains a hot topic. Doppler echocardiogram and strain echocardiography have shown significant predictive capacity for POAF.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Food Science & Technology
Andrew L. Waterhouse, Yingxin Miao
Summary: Oxidation is a limiting factor in wine aging, and antioxidant assays can be used to assess a wine's aging potential by measuring its capacity to chemically reduce reagent components. Flavanols show the highest correlation between antioxidant activity and wine components, and an ideal assay for wine aging capacity should respond selectively to specific functional groups. Comparing the various assays against the shelf life of commercial wines would be a definitive test.
Article
Reproductive Biology
Danyi Liu, Guorong Lyu, Hongwei Lai, Liya Li, Yaduan Gan, Shuping Yang
Summary: By retrospectively collecting data from 393 patients who met the inclusion criteria, we found that ultrasound MCP can accurately predict BOTs. Indicators that could well identify BOT in different pathological types of tumors were derived by multivariate unordered logistic regression analysis. The correlation between ultrasound MCP and pathological features was analyzed.
JOURNAL OF OVARIAN RESEARCH
(2023)
Article
Ecology
Loke von Schmalensee, Katrin Hulda Gunnarsdottir, Joacim Naslund, Karl Gotthard, Philipp Lehmann
Summary: This study demonstrates that it is challenging to predict the temperature dependence of performance traits in ectotherms in natural environments, despite being feasible in controlled laboratory settings. The research shows that accurate predictions of development rates in butterflies can be made in the field using models parameterized under constant laboratory temperatures, but this accuracy depends on considering non-linearity in reaction norms, spatial heterogeneity in microclimate, and temporal variation in temperature across microhabitats. Additionally, insect development rates are generally unaffected by thermal fluctuations, discounting direct effects of temperature.
Article
Astronomy & Astrophysics
Alina Sabyr, Zoltan Haiman, Jose Manuel Zorrilla Matilla, Tianhuan Lu
Summary: In order to extract full cosmological information from next-generation large and high-precision weak lensing surveys, it is necessary to utilize higher-order statistics that probe the small-scale, nonlinear regime of large-scale structure. WL peak counts, which trace overdensities in the cosmic web, are one promising and simple statistic for constraining cosmological parameters. However, halo-based models for WL peak counts do not explain all WL peaks, especially negative peaks, and neglecting nonhalo contributions leads to a significant bias on the parameters for surveys larger than 100 deg(2). Other elements of the cosmic web need to be incorporated into models of WL peaks in order to infer unbiased cosmological constraints.
Article
Pharmacology & Pharmacy
Kemiao Yuan, Songyun Zhao, Bicheng Ye, Qi Wang, Yuan Liu, Pengpeng Zhang, Jiaheng Xie, Hao Chi, Yu Chen, Chao Cheng, Jinhui Liu
Summary: The phenomenon of T Cell exhaustion (TEX) is the progressive deterioration in the functionality of T cells within the immune system during prolonged conflicts with chronic infections or tumors. In the context of ovarian cancer immunotherapy, understanding the features of TEX within the immune microenvironment is crucial for the management of OC patients.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Chemistry, Physical
Giovanna Bruno, Bernardo de Souza, Frank Neese, Giovanni Bistoni
Summary: This article proposes a computational strategy for accurate calculation of singlet-triplet gaps of aromatic compounds, which achieves excellent agreement with experimental data.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Surgery
Elisa Bertocchi, Giuliano Barugola, Marcello Ceccaroni, Massimo Guerriero, Roberto Rossini, Irene Gentile, Giacomo Ruffo
Summary: The study showed that DLS is a better predictor for anastomotic leakage (AL) and major complications, while CRP and PCT have limited predictive value on POD3 and POD6. There is a significant relationship between malnutrition and AL.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Multidisciplinary Sciences
Mary C. Politi, Catherine H. Saunders, Victoria F. Grabinski, Renata W. Yen, Amy E. Cyr, Marie-Anne Durand, Glyn Elwyn
Summary: Shared decision-making is recommended in medical decisions, but clinicians often guide patients subtly or explicitly; this study found that some surgeons tend to provide information and advice, while others are more likely to present comparable options, and surgeons using conversation aids are more likely to describe choices as comparable.
Article
Spectroscopy
Alexander A. Ksenofontov, Michail M. Lukanov, Pavel S. Bocharov
Summary: This article introduces a convenient tool for predicting the molar absorption coefficient of a wide range of dyes without any computer costs. The new model, based on the RFR method, achieves an accuracy of 0.26 log unit in predicting the molar absorption coefficient, thanks to being trained on data for over 20,000 unique dye molecules.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Nursing
Mohammadali Amini-Tehrani, Hadi Zamanian, Mona Daryaafzoon, Seyedehroja Andikolaei, Mahshid Mohebbi, Arefeh Imani, Bita Tahmasbi, Sahar Foroozanfar, Zahra Jalali
Summary: The study revealed that total stigma, enacted stigma, and internalized stigma among breast cancer patients play significant roles in predicting psychological distress, with stigma affecting distress through the mediation of body image.
JOURNAL OF ADVANCED NURSING
(2021)
Article
Endocrinology & Metabolism
Stephen J. Mooney, Lin Song, Adam Drewnowski, James Buskiewicz, Sean D. Mooney, Brian E. Saelens, David E. Arterburn
Summary: Health system clinical weight data can accurately estimate obesity prevalence in census tracts, showing a correlation in spatial distribution with lower educational attainment areas having higher obesity rates. This suggests that health system data can be a valuable resource for geographic obesity surveillance.
Article
Surgery
Jana de Boniface, Robert Szulkin, Anna L. Johansson
Summary: Older women with breast cancer have a higher risk of major medical complications after surgery, especially those who undergo mastectomy. The removal of the whole breast is associated with a higher risk of complications and worse survival in older patients. Mastectomy should be considered with caution in older women.
BRITISH JOURNAL OF SURGERY
(2023)
Article
Chemistry, Physical
Si Zhang, David F. Hahn, Michael R. Shirts, Vincent A. Voelz
Summary: Alchemical free energy methods are crucial in computational drug discovery for their accuracy in estimating protein-ligand affinities. Expanded ensemble methods show advantages in alchemical free energy calculations, but literature lacks examples of using this approach for protein-ligand binding. This study demonstrates the effectiveness of expanded ensemble methods in predicting relative binding free energies for Tyk2 inhibitors. The findings suggest ways to improve convergence and estimates in alchemical free energy calculations.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2021)