Spleen Tyrosine Kinase Modulates Fibrous Airway Obliteration and Associated Lymphoid Neogenesis After Transplantation

Syk mediates airway contractility independent of leukocyte function

(2015) X. Wang et al.   ALLERGY

Update on pathology of antibody-mediated rejection in the lung allograft

(2014) William D. Wallace et al.   Current Opinion in Organ Transplantation

Spleen tyrosine kinase inhibitors: a review of the patent literature 2010 – 2013

(2014) Peter Norman   EXPERT OPINION ON THERAPEUTIC PATENTS

Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat

(2014) Sharmila Ramessur Chandran et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease

(2014) Doanh Le Huu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Syk Associates with Clathrin and Mediates Phosphatidylinositol 3-Kinase Activation during Human Rhinovirus Internalization

(2014) C. Lau et al.   JOURNAL OF IMMUNOLOGY

Getting Syk: spleen tyrosine kinase as a therapeutic target

(2014) Robert L. Geahlen   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of Spleen Tyrosine Kinase Attenuates Allergen-Mediated Airway Constriction

(2013) Lily Y. Moy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impact of Cytokine Expression in the Pre-Implanted Donor Lung on the Development of Chronic Lung Allograft Dysfunction Subtypes

(2013) T. Saito et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases

(2013) H. Patterson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Adult Lung and Heart-Lung Transplant Report—2013; Focus Theme: Age

(2013) Roger D. Yusen et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome

(2013) Stijn E. Verleden et al.   TRANSPLANTATION

Spleen tyrosine kinase inhibition attenuates airway hyperresponsiveness and pollution-induced enhanced airway response in a chronic mouse model of asthma

(2012) Patricia Castellanos Penton et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Spleen Tyrosine Kinase Is Important in the Production of Proinflammatory Cytokines and Cell Proliferation in Human Mesangial Cells following Stimulation with IgA1 Isolated from IgA Nephropathy Patients

(2012) M. J. Kim et al.   JOURNAL OF IMMUNOLOGY

Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration

(2012) J Hoellenriegel et al.   LEUKEMIA

Chronic Rejection Pathology after Orthotopic Lung Transplantation in Mice: The Development of a Murine BOS Model and Its Drawbacks

(2012) Stéphanie De Vleeschauwer et al.   PLoS One

Rejection of Tracheal Allograft by Intrapulmonary Lymphoid Neogenesis in the Absence of Secondary Lymphoid Organs

(2012) Dirk Wagnetz et al.   TRANSPLANTATION

Neutralizing IL-17 Prevents Obliterative Bronchiolitis in Murine Orthotopic Lung Transplantation

(2011) L. Fan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

(2011) Brit Neuhaus et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Azithromycin in Posttransplant Bronchiolitis Obliterans Syndrome

(2011) Robin Vos et al.   CHEST

Chronic Allograft Dysfunction

(2011) Christiane Knoop et al.   CLINICS IN CHEST MEDICINE

Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo

(2011) Eva Wex et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A review of bronchiolitis obliterans syndrome and therapeutic strategies

(2011) Don Hayes   Journal of Cardiothoracic Surgery

HRV Signaling in Airway Epithelial Cells Is Regulated by ITAM-Mediated Recruitment and Activation of Syk

(2011) Christine Lau et al.   PROTEIN AND PEPTIDE LETTERS

Stromal Activation and Formation of Lymphoid-Like Stroma in Chronic Lung Allograft Dysfunction

(2011) Masaaki Sato et al.   TRANSPLANTATION

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia

(2010) M. Buchner et al.   BLOOD

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

(2010) Michael E. Weinblatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chronic Allograft Rejection: Epidemiology, Diagnosis, Pathogenesis, and Treatment

(2010) S. Weigt et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Src-family and Syk Kinases in Activating and Inhibitory Pathways in Innate Immune Cells: Signaling Cross Talk

(2010) C. A. Lowell   Cold Spring Harbor Perspectives in Biology

CXCL12 and CXCR4 in bone marrow physiology

(2010) Natalia M Moll et al.   Expert Review of Hematology

Aspergillus Colonization of the Lung Allograft Is a Risk Factor for Bronchiolitis Obliterans Syndrome

(2009) S. S. Weigt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406

(2009) M. P. Quiroga et al.   BLOOD

Effect of Etiology and Timing of Respiratory Tract Infections on Development of Bronchiolitis Obliterans Syndrome

(2009) Vincent G. Valentine et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The Role of Intrapulmonary De Novo Lymphoid Tissue in Obliterative Bronchiolitis after Lung Transplantation

(2009) M. Sato et al.   JOURNAL OF IMMUNOLOGY

Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells

(2009) X. Zhang et al.   MOLECULAR CANCER RESEARCH

Pseudomonas aeruginosa Colonization of the Allograft After Lung Transplantation and the Risk of Bronchiolitis Obliterans Syndrome

(2009) Phil Botha et al.   TRANSPLANTATION

De Novo or Persistent Pseudomonal Airway Colonization After Lung Transplantation: Importance for Bronchiolitis Obliterans Syndrome?

(2008) Robin Vos et al.   TRANSPLANTATION