Article
Veterinary Sciences
Mathilde L. Pas, Kevin Vanneste, Jade Bokma, Laura Van Driessche, Sigrid C. J. De Keersmaecker, Nancy H. Roosens, Freddy Haesebrouck, Filip Boyen, Bart Pardon
Summary: This report presents a case of sepsis in a calf caused by a multidrug resistant Raoultella ornithinolytica, highlighting the need for rapid and appropriate treatment. Whole genome sequencing confirmed the identification of the pathogen and its drug resistant qualities. The calf recovered with empirical parenteral therapy and ancillary treatment. Further investigation is needed to determine if animals and farms could be reservoirs for such resistant strains.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Infectious Diseases
Xiaonan Chen, Xinjian Zhou, Jun Cao, Ke Ma, Zhijie Xia
Summary: Raoultella ornithinolytica is a Gram-negative bacillus that can cause healthcare-associated infections. This case report describes a 25-year-old patient with R. ornithinolytica infection presenting with fever, rash, and lymph node enlargement. Treatment with meropenem and loratadine was successful in managing the infection and associated allergic reaction.
BMC INFECTIOUS DISEASES
(2021)
Article
Microbiology
Jose E. Villacis, Hugo G. Castelan-Sanchez, Jorge Rojas-Vargas, Ulises E. Rodriguez-Cruz, Viviana Alban, Jorge A. Reyes, Pablo M. Meza-Rodriguez, Sonia Davila-Ramos, Fernando Villavicencio, Margarita Galarza, Monica C. Gestal
Summary: This study aimed to investigate the clinical and molecular features of Raoultella ornithinolytica strains isolated from clinical environments in Ecuador, and to compare their genomes with previously published genomes of Raoultella spp. The results revealed the genome plasticity of R. ornithinolytica and its ability to acquire antibiotic resistance genes, highlighting the importance of genomic surveillance and infectious control for these uncommon species.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Immunology
Deniz Yaprak, Mina Misirligil, Ali Dinc Bozat, Belma Saygili Karagol
Summary: This article presents a rare case of community-acquired Raoultella ornithinolytica septicemia in a neonate and reviews the literature on ROS in the neonatal period, emphasizing the importance of early diagnosis and appropriate antibiotics for a good prognosis in neonatal septicemia.
PEDIATRIC INFECTIOUS DISEASE JOURNAL
(2021)
Article
Microbiology
Cheng-Zhen Wang, Xun Gao, Qi-Wen Yang, Lu-Chao Lv, Miao Wan, Jun Yang, Zhong-Peng Cai, Jian-Hua Liu
Summary: The study identified a novel mobile gene cluster, tmexCD2-toprJ2, present in Raoultella ornithinolytica, which confers resistance to multiple antimicrobials and may have originated from a Pseudomonas species. The expression of tmexCD2-toprJ2 in Escherichia coli resulted in increased resistance to tigecycline and decreased susceptibility to other antimicrobials. Genetic context analyses demonstrated that tmexCD2-toprJ2 might have been captured and mobilized by a XerD-like tyrosine recombinase system.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Microbiology
Iliana Alejandra Cortes-Ortiz, Edgar Mendieta-Condado, Noe Escobar-Escamilla, Julio Cesar Juarez-Gomez, Fabiola Garces-Ayala, Adnan Araiza Rodriguez, Juan Carlos Bravata-Alcantara, Victor Hugo Gutierrez-Munoz, Juan Manuel Bello-Lopez, Jose Ernesto Ramirez-Gonzalez
Summary: Class D beta-lactamases OXA-232 and OXA-48 were found to hydrolyze penicillin, cephalosporins, and carbapenems, limiting therapeutic options for bacteraemia. The study identified Raoultella ornithinolytica carrying OXA 232 and OXA-48 genes, confirming the results of the beta-lactamases assay. This represents the first report of multidrug resistance R. ornithinolytica in Mexico, highlighting the emergence of OXA producer microorganisms as a significant threat.
ARCHIVES OF MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Laila Ibrahim Faqe Salih, Rezan Omer Rasheed, Sirwan Muhsin Muhammed
Summary: In this study, metal-resistant Raoultella ornithinolytica was isolated from metal-contaminated samples collected from the Tanjaro River in Sulaymaniyah, Iraq. The bacterium showed high removal rates for various heavy metals and had capabilities to remove metals under different conditions. It can be used as an eco-friendly biological expedient for the remediation and detoxification of metals from contaminated environments.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Genetics & Heredity
Marjorie J. Gibbon, Natacha Couto, Sophia David, Ruth Barden, Richard Standerwick, Kishore Jagadeesan, Hollie Birkwood, Punyawee Dulyayangkul, Matthew B. Avison, Andrew Kannan, Dan Kibbey, Tim Craft, Samia Habib, Harry A. Thorpe, Jukka Corander, Barbara Kasprzyk-Hordern, Edward J. Feil
Summary: Hospital wastewater serves as an important reservoir for antibiotic-resistant Klebsiella, with species within the Raoultella group playing an unexpected role in the maintenance and dissemination of plasmid-borne bla(OXA-48) gene.
MICROBIAL GENOMICS
(2021)
Article
Medical Laboratory Technology
In Young Yoo, Woong Heo, Joo An Kwon, Miran Lee, Yeon-Joon Park
Summary: Diabetic foot infection is a common complication of diabetes mellitus, and besides bacterial infections, fungal infections can also cause such infections. This study reports a case of diabetic foot infection caused by Cutaneotrichosporon debeurmannianum.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2022)
Article
Medicine, General & Internal
Juan Camilo Motta, Enrique Ucros, Mariana Reyes Rey, Paula Daniela Gomez, Magda Sanchez
Summary: Raoultella spp. is increasingly isolated in immunocompromised patients with multiple comorbidities, and there is a growing concern about the presence of multi-drug resistant strains.
Article
Environmental Sciences
Nai-Xian Feng, Fei Zhang, Yunchang Xie, Hui Bin, Lei Xiang, Yan-Wen Li, Fantao Zhang, Yunhong Huang, Hai -Ming Zhao, Quan-Ying Cai, Ce-Hui Mo, Qing X. Li
Summary: Genome mining identified bacteria with potential to degrade phthalates (PAEs), which are widely present in soils and food products and pose a high risk to human health. Ribosome engineering was used to activate the expression of key genes involved in PAEs biodegradation, resulting in a mutant strain XF201-G2U5 that showed high activity in degrading di-n butyl phthalate (DBP) and other PAEs. This strategy enables the discovery of novel bacterial resources for the bioremediation of PAEs and other emerging contaminants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Infectious Diseases
Sai Vikram Alampoondi Venkataramanan, Lovin George, Kamal Kant Sahu, George M. Abraham
Summary: This study identified 37 cases of UTI caused by Raoultella planticola over a 5-year period, with a mean patient age of 77 years. The most common comorbidity was diabetes mellitus, and common presenting complaints were altered mental status and fever. Resistance to ampicillin was high in isolates, with some also being multidrug-resistant but susceptible to ciprofloxacin. The severity of infection ranged from simple cystitis to septic shock, but there were no mortalities in the cohort.
INFECTION AND DRUG RESISTANCE
(2021)
Review
Endocrinology & Metabolism
Fang Du, Jing Ma, Hongping Gong, Raju Bista, Panpan Zha, Yan Ren, Yun Gao, Dawei Chen, Xingwu Ran, Chun Wang
Summary: This study investigated the microbial spectrum isolated from foot ulcers among diabetic patients in China and found a diverse range of infectious agents. The prevalence of different microbes varied across geographic regions, with Staphylococcus aureus being the most common bacterium detected. The study also revealed the common occurrence of polymicrobial and multidrug-resistant infections in foot ulcers. The findings of this study are valuable for guiding the empirical use of antibiotics for diabetic foot infections.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Michal Zloch, Ewelina Maslak, Wojciech Kupczyk, Marek Jackowski, Pawel Pomastowski, Boguslaw Buszewski
Summary: This study evaluated the use of different culture media in reflecting the microbial compositions of diabetic foot infections in Poland. The results showed significant differences in species coverage and efficiency between the investigated media. Selecting the appropriate media set can significantly improve the accuracy of reflecting the microbial compositions of diabetic foot infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Medicine, General & Internal
Wei Chai, Yuqing Wang, Huancheng Zheng, Song Yue, Yan Liu, Yili Wu, Xuezhi Li
Summary: The study analyzed the pathogen spectrum and antibiotic susceptibility of diabetic foot ulcers, finding that dominant pathogens were sensitive to at least one antibiotic, but the antibacterial efficacy of common antibiotics decreased over time. Identification and testing of antibiotic susceptibility of dominant pathogens are essential for effective treatment of diabetic foot ulcers.
FRONTIERS IN MEDICINE
(2021)
