Roflumilast: A Novel Treatment for Chronic Obstructive Pulmonary Disease

ABCD of the phosphodiesterase family: interaction and differential activity in COPD

(2016) David Halpin   International Journal of Chronic Obstructive Pulmonary Disease

Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease

(2011) Klaus F. Rabe   BRITISH JOURNAL OF PHARMACOLOGY

Effect of repeated dose of erythromycin on the pharmacokinetics of roflumilast and roflumilast N-oxide

(2011) G. Lahu et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Treatment of Chronic Obstructive Pulmonary Disease with Roflumilast, a New Phosphodiesterase 4 Inhibitor

(2010) Nicholas J. Gross et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

The preclinical pharmacology of roflumilast – A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease

(2010) Armin Hatzelmann et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Costs of inpatient and emergency department care for chronic obstructive pulmonary disease in an elderly Medicare population

(2010) Anand A. Dalal et al.   JOURNAL OF MEDICAL ECONOMICS

Effects of rifampicin on the pharmacokinetics of roflumilast and roflumilast N-oxide in healthy subjects

(2009) Nassr Nassr et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

PDE4 inhibitors: a review of current developments (2005 – 2009)

(2009) Lluís Pagès et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

(2009) Leonardo M Fabbri et al.   LANCET

Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials

(2009) Peter MA Calverley et al.   LANCET

Effect of Single and Repeated Doses of Ketoconazole on the Pharmacokinetics of Roflumilast and Roflumilast N-Oxide

(2008) Gezim Lahu et al.   JOURNAL OF CLINICAL PHARMACOLOGY