Lubiprostone for Constipation in Adults with Cystic Fibrosis: A Pilot Study

Clinical trial: phase 2 study of lubiprostone for irritable bowel syndrome with constipation

(2010) J. F. JOHANSON et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Use of the Chloride Channel Activator Lubiprostone for Constipation in Adults with Cystic Fibrosis: A Case Series

(2010) Catherine E O'Brien et al.   ANNALS OF PHARMACOTHERAPY

Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype

(2010) Robert C De Lisle et al.   BMC GASTROENTEROLOGY

Lubiprostone Activates Cl− Secretion via cAMP Signaling and Increases Membrane CFTR in the Human Colon Carcinoma Cell Line, T84

(2010) Mei Ao et al.   DIGESTIVE DISEASES AND SCIENCES

Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon

(2009) Guijun Fei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lubiprostone Stimulates Duodenal Bicarbonate Secretion in Rats

(2009) Misa Mizumori et al.   DIGESTIVE DISEASES AND SCIENCES

Efficacy and Safety of Lubiprostone in Patients with Chronic Constipation

(2009) Charles F. Barish et al.   DIGESTIVE DISEASES AND SCIENCES

Activation of Intestinal Cl− Secretion by Lubiprostone Requires the Cystic Fibrosis Transmembrane Conductance Regulator

(2009) Marcel J.C. Bijvelds et al.   GASTROENTEROLOGY

Constipation in pediatric Cystic Fibrosis patients: An underestimated medical condition

(2009) H.P.J. van der Doef et al.   Journal of Cystic Fibrosis

Defining DIOS and Constipation in Cystic Fibrosis With a Multicentre Study on the Incidence, Characteristics, and Treatment of DIOS

(2009) Roderick H Houwen et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

A synthetic prostone activates apical chloride channels in A6 epithelial cells

(2008) Hui Fang Bao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice

(2008) Kelvin D. MacDonald et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Multicenter, 4-Week, Double-Blind, Randomized, Placebo-Controlled Trial of Lubiprostone, a Locally-Acting Type-2 Chloride Channel Activator, in Patients With Chronic Constipation

(2007) John F Johanson et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR

(2007) L J MacVinish et al.   BRITISH JOURNAL OF PHARMACOLOGY