Certolizumab Pegol: A TNF-α Antagonist for the Treatment of Moderate-to-Severe Crohn's Disease

CIMZIA (Certolizumab Pegol) is effective in the treatment of Crohnʼs Disease patients with open fistulas

(2012) S Schreiber et al.   INFLAMMATORY BOWEL DISEASES

Certolizumab pegol—what role does this new TNF inhibitor have in the treatment of RA?

(2009) Daniel E Furst   Nature Reviews Rheumatology

Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial

(2008) J Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study

(2008) R Fleischmann et al.   ANNALS OF THE RHEUMATIC DISEASES

Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials

(2008) C Salliot et al.   ANNALS OF THE RHEUMATIC DISEASES

Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

(2008) Edward Keystone et al.   ARTHRITIS AND RHEUMATISM

A PEGylated Fab′ Fragment against Tumor Necrosis Factor for the Treatment of Crohn Disease

(2008) Tim Bourne et al.   BIODRUGS

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Successful induction of clinical response and remission with certolizumab pegol in Crohnʼs disease patients refractory or intolerant to infliximab: A real-life multicenter experience of compassionate use

(2008) Silvio Danese et al.   INFLAMMATORY BOWEL DISEASES

Successful treatment of fistulizing Crohnʼs disease with certolizumab pegol

(2007) Silvio Danese et al.   INFLAMMATORY BOWEL DISEASES

Tumor necrosis factor antagonist mechanisms of action: A comprehensive review

(2007) Daniel Tracey et al.   PHARMACOLOGY & THERAPEUTICS