Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease

Genotype–phenotype correlations in neurogenetics: Lesch-Nyhan disease as a model disorder

(2013) Rong Fu et al.   BRAIN

Purine metabolism during neuronal differentiation: the relevance of purine synthesis and recycling

(2013) Martin Göttle et al.   JOURNAL OF NEUROCHEMISTRY

Regional brain volume abnormalities in Lesch-Nyhan disease and its variants: a cross-sectional study

(2013) David J Schretlen et al.   LANCET NEUROLOGY

The Housekeeping Gene Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Regulates Multiple Developmental and Metabolic Pathways of Murine Embryonic Stem Cell Neuronal Differentiation

(2013) Tae Hyuk Kang et al.   PLoS One

Developmental origins of brain disorders: roles for dopamine

(2013) Kelli M. Money et al.   Frontiers in Cellular Neuroscience

MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch–Nyhan disease?

(2011) Ghiabe-Henri Guibinga et al.   HUMAN MOLECULAR GENETICS

Levodopa is not a useful treatment for Lesch-Nyhan disease

(2011) Jasper E. Visser et al.   MOVEMENT DISORDERS

HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developmental Regulatory Role for a Housekeeping Gene?

(2011) Tae Hyuk Kang et al.   PLoS One

Lesch-Nyhan disease: from mechanism to model and back again

(2009) H. A. Jinnah   Disease Models & Mechanisms

Hypoxanthine-guanine phosphoribosyl transferase regulates early developmental programming of dopamine neurons: implications for Lesch-Nyhan disease pathogenesis

(2009) I. Ceballos-Picot et al.   HUMAN MOLECULAR GENETICS

Deficiency of the Housekeeping Gene Hypoxanthine–Guanine Phosphoribosyltransferase (HPRT) Dysregulates Neurogenesis

(2009) Ghiabe-Henri Guibinga et al.   MOLECULAR THERAPY

Convergent evidence for abnormal striatal synaptic plasticity in dystonia

(2009) David A. Peterson et al.   NEUROBIOLOGY OF DISEASE

Consequences of impaired purine recycling in dopaminergic neurons

(2008) J.C. Lewers et al.   NEUROSCIENCE

Transcriptional regulation of mesencephalic dopaminergic neurons: The full circle of life and death

(2007) Kambiz N. Alavian et al.   MOVEMENT DISORDERS