Epigenetic promoter silencing in Friedreich ataxia is dependent on repeat length

Altered Nucleosome Positioning at the Transcription Start Site and Deficient Transcriptional Initiation in Friedreich Ataxia

(2014) Yogesh K. Chutake et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study

(2014) Vincenzo Libri et al.   LANCET

Rating disease progression of Friedreich’s ataxia by the International Cooperative Ataxia Rating Scale: analysis of a 603-patient database

(2013) Günther Metz et al.   BRAIN

Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3

(2013) P. K. Chan et al.   HUMAN MOLECULAR GENETICS

Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia

(2013) Joel M. Gottesfeld et al.   JOURNAL OF NEUROCHEMISTRY

Development of Frataxin Gene Expression Measures for the Evaluation of Experimental Treatments in Friedreich’s Ataxia

(2013) Heather L. Plasterer et al.   PLoS One

Analysis of Echocardiograms in a Large Heterogeneous Cohort of Patients With Friedreich Ataxia

(2011) Sean R. Regner et al.   AMERICAN JOURNAL OF CARDIOLOGY

FXN methylation predicts expression and clinical outcome in Friedreich ataxia

(2011) Marguerite V. Evans-Galea et al.   ANNALS OF NEUROLOGY

Repeat Expansion Affects Both Transcription Initiation and Elongation in Friedreich Ataxia Cells

(2010) Daman Kumari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY