Everolimus treatment of refractory epilepsy in tuberous sclerosis complex

Long-term effect of everolimus on epilepsy and growth in children under 3 years of age treated for subependymal giant cell astrocytoma associated with tuberous sclerosis complex

(2013) Katarzyna Kotulska et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Nursing Implications for the Lifelong Management of Tuberous Sclerosis Complex

(2013) Karen Agricola et al.   JOURNAL OF NEUROSCIENCE NURSING

Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial

(2013) John J Bissler et al.   LANCET

Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma

(2013) D. A. Krueger et al.   NEUROLOGY

Rapamycin Attenuates the Development of Posttraumatic Epilepsy in a Mouse Model of Traumatic Brain Injury

(2013) Dongjun Guo et al.   PLoS One

Rapamycin Prevents Seizures After Depletion of STRADA in a Rare Neurodevelopmental Disorder

(2013) W. E. Parker et al.   Science Translational Medicine

Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial

(2012) David Neal Franz et al.   LANCET

De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly

(2012) Jeong Ho Lee et al.   NATURE GENETICS

Everolimus alters white matter diffusion in tuberous sclerosis complex

(2012) J.-M. Tillema et al.   NEUROLOGY

mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy

(2012) Emilio Russo et al.   NEUROPHARMACOLOGY

Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy

(2012) X. Huang et al.   NEUROSCIENCE

Mapping the Spatio-Temporal Pattern of the Mammalian Target of Rapamycin (mTOR) Activation in Temporal Lobe Epilepsy

(2012) Long-Ze Sha et al.   PLoS One

Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice

(2011) C. Nicole Sunnen et al.   EPILEPSIA

Antiepileptic treatment before the onset of seizures reduces epilepsy severity and risk of mental retardation in infants with tuberous sclerosis complex

(2011) Sergiusz Jóźwiak et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis

(2011) Francis X. McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epilepsy secondary to tuberous sclerosis: lessons learned and current challenges

(2010) Romina Moavero et al.   CHILDS NERVOUS SYSTEM

Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

(2010) Xiaoxing Huang et al.   NEUROBIOLOGY OF DISEASE

Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis

(2010) Darcy A. Krueger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia

(2009) M. C. Ljungberg et al.   Disease Models & Mechanisms

Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies

(2009) Michael Wong   EPILEPSIA

Rapamycin Reduces Seizure Frequency in Tuberous Sclerosis Complex

(2009) Jennifer Muncy et al.   JOURNAL OF CHILD NEUROLOGY

The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy

(2009) L.-H. Zeng et al.   JOURNAL OF NEUROSCIENCE

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

Recent advances in neurobiology of Tuberous Sclerosis Complex

(2008) Valerio Napolioni et al.   BRAIN & DEVELOPMENT

The Nisonger Child Behavior Rating Form: typical IQ version

(2008) Michael Aman et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE

Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis

(2008) Dan Ehninger et al.   NATURE MEDICINE

Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis

(2008) John J. Bissler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Current Management of Tuberous Sclerosis Complex

(2008) Darcy A Krueger et al.   PEDIATRIC DRUGS