Early interneuron dysfunction in ALS: Insights from a mutantsod1zebrafish model

Does interneuronal dysfunction contribute to neurodegeneration in amyotrophic lateral sclerosis?

(2012) Martin R. Turner et al.   Amyotrophic Lateral Sclerosis

An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1

(2012) S. Guareschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders

(2011) Mathias Jucker et al.   ANNALS OF NEUROLOGY

Autophagy inhibition engages Nrf2-p62 Ub-associated signaling

(2011) Brigit E. Riley et al.   Autophagy

The Seeds of Neurodegeneration: Prion-like Spreading in ALS

(2011) Magdalini Polymenidou et al.   CELL

Spinal Inhibitory Interneuron Pathology Follows Motor Neuron Degeneration Independent of Glial Mutant Superoxide Dismutase 1 Expression in SOD1-ALS Mice

(2011) Mehdi Hossaini et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Glycine Receptor Channels in Spinal Motoneurons Are Abnormal in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

(2011) Q. Chang et al.   JOURNAL OF NEUROSCIENCE

Inhibitory Synaptic Regulation of Motoneurons: A New Target of Disease Mechanisms in Amyotrophic Lateral Sclerosis

(2011) Lee J. Martin et al.   MOLECULAR NEUROBIOLOGY

Generation and Characterization of a genetic zebrafish model of SMA carrying the human SMN2 gene

(2011) Le T Hao et al.   Molecular Neurodegeneration

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

(2011) Laura Ferraiuolo et al.   Nature Reviews Neurology

A yeast functional screen predicts new candidate ALS disease genes

(2011) J. Couthouis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Stress of Protein Misfolding: From Single Cells to Multicellular Organisms

(2011) T. Gidalevitz et al.   Cold Spring Harbor Perspectives in Biology

Circuit Neuroscience in Zebrafish

(2010) Rainer W. Friedrich et al.   CURRENT BIOLOGY

A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease

(2010) T. Ramesh et al.   Disease Models & Mechanisms

Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice

(2010) Margaret Wong et al.   HUMAN MOLECULAR GENETICS

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

(2010) Brigit E. Riley et al.   JOURNAL OF CELL BIOLOGY

Energy metabolism in amyotrophic lateral sclerosis

(2010) Luc Dupuis et al.   LANCET NEUROLOGY

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

(2010) Daryl A Bosco et al.   NATURE NEUROSCIENCE

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Review: Neuromuscular synaptic vulnerability in motor neurone disease: amyotrophic lateral sclerosis and spinal muscular atrophy

(2010) L. M. Murray et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Nerve Terminal Degeneration Is Independent of Muscle Fiber Genotype in SOD1G93A Mice

(2010) Dario I. Carrasco et al.   PLoS One

Motor Network Degeneration in Amyotrophic Lateral Sclerosis: A Structural and Functional Connectivity Study

(2010) Esther Verstraete et al.   PLoS One

Early Excitability Changes in Lumbar Motoneurons of Transgenic SOD1G85R and SOD1G93A-Low Mice

(2009) Arnaud Pambo-Pambo et al.   JOURNAL OF NEUROPHYSIOLOGY

Genetics of motor neuron disorders: new insights into pathogenic mechanisms

(2009) Patrick A. Dion et al.   NATURE REVIEWS GENETICS

Circuits controlling vertebrate locomotion: moving in a new direction

(2009) Martyn Goulding   NATURE REVIEWS NEUROSCIENCE

ALS motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degeneration

(2009) J. M. Ravits et al.   NEUROLOGY

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

(2008) Steve Vucic et al.   BRAIN

Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons

(2008) Manuel F. Batista et al.   DEVELOPMENTAL BIOLOGY

From clues to mechanisms: Understanding ALS initiation and spread

(2008) C. Armon   NEUROLOGY

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS

(2008) B TURNER et al.   PROGRESS IN NEUROBIOLOGY