Molecular pathways and targets in cancer-related inflammation

Oxidative Stress Regulates Expression of VEGFR1 in Myeloid Cells: Link to Tumor-Induced Immune Suppression in Renal Cell Carcinoma

(2014) S. Kusmartsev et al.   JOURNAL OF IMMUNOLOGY

Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway

(2014) H. Shime et al.   JOURNAL OF IMMUNOLOGY

Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment

(2009) Marcin Kortylewski et al.   CANCER CELL

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Host-Derived Interleukin-1  Is Important in Determining the Immunogenicity of 3-Methylcholantrene Tumor Cells

(2009) M. Elkabets et al.   JOURNAL OF IMMUNOLOGY

Inflaming metastasis

(2009) Alberto Mantovani   NATURE

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling

(2008) R. J. Byers et al.   BLOOD

Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3

(2008) Y.-C. Chang et al.   BLOOD

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

(2008) Y. Sawanobori et al.   BLOOD

Matrix Metalloproteinase-9 Is Required for Tumor Vasculogenesis but Not for Angiogenesis: Role of Bone Marrow-Derived Myelomonocytic Cells

(2008) G-One Ahn et al.   CANCER CELL

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

(2008) Toshiharu Sakurai et al.   CANCER CELL

Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?

(2008) Sergei Grivennikov et al.   CANCER CELL

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

(2008) Li Yang et al.   CANCER CELL

A Catalytic Role for Proangiogenic Marrow-Derived Cells in Tumor Neovascularization

(2008) Marco Seandel et al.   CANCER CELL

A Macrophage Gene Expression Signature Defines a Field Effect in the Lung Tumor Microenvironment

(2008) R. S. Stearman et al.   CANCER RESEARCH

Inflammatory Cytokines Induce Phosphorylation and Ubiquitination of Prostate Suppressor Protein NKX3.1

(2008) M. C. Markowski et al.   CANCER RESEARCH

Circulating Colony Stimulating Factor-1 and Breast Cancer Risk

(2008) R. M. Tamimi et al.   CANCER RESEARCH

The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma

(2008) Federica Marchesi et al.   CANCER RESEARCH

Vascular Endothelial Growth Factor Receptor 2 Mediates Macrophage Infiltration into Orthotopic Pancreatic Tumors in Mice

(2008) S. P. Dineen et al.   CANCER RESEARCH

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

(2008) Keisuke Oguma et al.   EMBO JOURNAL

Activated neutrophils induce an hMSH2-dependent G2/M checkpoint arrest and replication errors at a (CA)13-repeat in colon epithelial cells

(2008) C Campregher et al.   GUT

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

(2008) Paola Allavena et al.   IMMUNOLOGICAL REVIEWS

Opposing effects of fibrosarcoma cell-derived IL-1α and IL-1β on immune response induction

(2008) Rachid Marhaba et al.   INTERNATIONAL JOURNAL OF CANCER

Breast cancer expression of CD163, a macrophage scavenger receptor, is related to early distant recurrence and reduced patient survival

(2008) Ivan Shabo et al.   INTERNATIONAL JOURNAL OF CANCER

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

(2008) Charlotte Rolny et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens

(2008) Maciej Lech et al.   JOURNAL OF EXPERIMENTAL MEDICINE

“Re-educating” tumor-associated macrophages by targeting NF-κB

(2008) Thorsten Hagemann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

(2008) Jose Rafael Sierra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer

(2008) Willscott E. Naugler et al.   TRENDS IN MOLECULAR MEDICINE