MicroRNAs mark in the MLL-rearranged leukemia

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

(2012) Guillermo Senisterra et al.   BIOCHEMICAL JOURNAL

microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming

(2012) Meng Amy Li et al.   BIOESSAYS

A novel hierarchical prognostic model of AML solely based on molecular mutations

(2012) V. Grossmann et al.   BLOOD

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

(2012) A. Shi et al.   BLOOD

MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia

(2012) X.-S. Wang et al.   BLOOD

Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

(2012) Xi Jiang et al.   CANCER CELL

Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing

(2012) Blerta Xhemalce et al.   CELL

Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals

(2012) Ryuya Fukunaga et al.   CELL

miRNAs involved in the generation, maintenance, and differentiation of pluripotent cells

(2012) Nils Pfaff et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Clinical Outcome Prediction by MicroRNAs in Human Cancer: A Systematic Review

(2012) Viswam S. Nair et al.   JNCI-Journal of the National Cancer Institute

Novel classes of non-coding RNAs and cancer

(2012) Jiri Sana et al.   Journal of Translational Medicine

microRNAs in cancer management

(2012) Yi W Kong et al.   LANCET ONCOLOGY

The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia

(2012) S P Whitman et al.   LEUKEMIA

MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte–erythroid progenitor lineage commitment

(2012) L Zhang et al.   LEUKEMIA

MicroRNAs Mediate Gene Silencing via Multiple Different Pathways in Drosophila

(2012) Takashi Fukaya et al.   MOLECULAR CELL

Genetic and clinical characterization of 45 acute leukemia patients with MLL gene rearrangements from a single institution

(2012) Nuno Cerveira et al.   Molecular Oncology

The functions of microRNAs in pluripotency and reprogramming

(2012) Trevor R. Leonardo et al.   NATURE CELL BIOLOGY

MicroRNA expression and activity in pediatric acute lymphoblastic leukemia (ALL)

(2012) Jaqueline C. de Oliveira et al.   PEDIATRIC BLOOD & CANCER

miR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia

(2012) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNase III-independent microRNA biogenesis in mammalian cells

(2012) T. Maurin et al.   RNA

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish

(2012) A. A. Bazzini et al.   SCIENCE

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia

(2012) Zejuan Li et al.   Nature Communications

Small RNAs derived from longer non-coding RNAs

(2011) Susanne Röther et al.   BIOCHIMIE

MLL-SEPTIN gene fusions in hematological malignancies

(2011) Nuno Cerveira et al.   BIOLOGICAL CHEMISTRY

MicroRNA function in myeloid biology

(2011) R. M. O'Connell et al.   BLOOD

Dynamics of epigenetic modifications in leukemia

(2011) I. Uribesalgo et al.   Briefings in Functional Genomics

MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML

(2011) Yin Xiong et al.   BRITISH JOURNAL OF HAEMATOLOGY

Deregulated microRNAs in multiple myeloma

(2011) Leonidas Benetatos et al.   CANCER

Micro RNAs as a new therapeutic target towards leukaemia signalling

(2011) Megan Y. Murray et al.   CELLULAR SIGNALLING

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

MicroRNA programs in normal and aberrant stem and progenitor cells

(2011) C. P. Arnold et al.   GENOME RESEARCH

MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

(2011) D. Schotte et al.   HAEMATOLOGICA

MicroRNAs regulatory networks in myeloid lineage development and differentiation: regulators of the regulators

(2011) Mohamed El Gazzar et al.   IMMUNOLOGY AND CELL BIOLOGY

Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications

(2011) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

MicroRNAs in acute leukemia: from biological players to clinical contributors

(2011) D Schotte et al.   LEUKEMIA

RETRACTED: The Noncoding RNA Mistral Activates Hoxa6 and Hoxa7 Expression and Stem Cell Differentiation by Recruiting MLL1 to Chromatin

(2011) Stéphane Bertani et al.   MOLECULAR CELL

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

(2011) Mark A. Dawson et al.   NATURE

Methylation-mediated repression of microRNA-143 enhances MLL–AF4 oncogene expression

(2011) L Dou et al.   ONCOGENE

Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia

(2011) Astrid A. Danen-van Oorschot et al.   PEDIATRIC BLOOD & CANCER

Targeting Epigenetic Programs in MLL-Rearranged Leukemias

(2011) K. M. Bernt et al.   Hematology-American Society of Hematology Education Program

Acute Myeloid Leukemia With t(9;11)(p21–22;q23)

(2010) Pranil Chandra et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Alteration of processing induced by a single nucleotide polymorphism in pri-miR-126

(2010) Ratanakanit Harnprasopwat et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interplay between microRNAs and the epigenetic machinery: An intricate network

(2010) Marilena V. Iorio et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Non-coding RNAs and their epigenetic regulatory mechanisms

(2010) Huihui Zhou et al.   BIOLOGY OF THE CELL

The prognostic and functional role of microRNAs in acute myeloid leukemia

(2010) G. Marcucci et al.   BLOOD

MLL fusions: Pathways to leukemia

(2010) Han Liu et al.   CANCER BIOLOGY & THERAPY

The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression

(2010) Piu Wong et al.   CANCER RESEARCH

A MicroRNA Targeting Dicer for Metastasis Control

(2010) Graziano Martello et al.   CELL

A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 Acute Lymphocytic Leukemia cells

(2010) Ai Kotani et al.   CELL CYCLE

MicroRNAs in chronic lymphocytic leukemia

(2010) Brian P. Ward et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing

(2010) Khairul I. Ansari et al.   FEBS Journal

Mixed lineage leukemia: a structure-function perspective of the MLL1 protein

(2010) Michael S. Cosgrove et al.   FEBS Journal

Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

(2010) D. Schotte et al.   HAEMATOLOGICA

Small RNAs Guide Hematopoietic Cell Differentiation and Function

(2010) F. Navarro et al.   JOURNAL OF IMMUNOLOGY

Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale

(2010) D J P M Stumpel et al.   LEUKEMIA

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

(2010) Shuangli Mi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

(2009) R. Popovic et al.   BLOOD

Therapeutic targeting of MLL

(2009) M. Liedtke et al.   BLOOD

miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221

(2009) A. Kotani et al.   BLOOD

Consistent Deregulation of Gene Expression between Human and Murine MLL Rearrangement Leukemias

(2009) Z. Li et al.   CANCER RESEARCH

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells

(2009) Tim C.P. Somervaille et al.   Cell Stem Cell

MicroRNA and leukemia: Tiny molecule, great function

(2009) Haifeng Zhao et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The molecular biology of mixed lineage leukemia

(2009) R. K. Slany   HAEMATOLOGICA

Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation

(2009) A R R Forrest et al.   LEUKEMIA

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell

(2009) G. Sotiropoulou et al.   RNA

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

Malignant Transformation Initiated by Mll-AF9: Gene Dosage and Critical Target Cells

(2008) Weili Chen et al.   CANCER CELL

Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia

(2008) D Schotte et al.   LEUKEMIA

MicroRNA-126 Regulates HOXA9 by Binding to the Homeobox

(2008) W.-F. Shen et al.   MOLECULAR AND CELLULAR BIOLOGY

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA