CD44 in hematological neoplasias

Hyaluronan Induces Cell Death in Activated T Cells through CD44

(2014) B. Ruffell et al.   JOURNAL OF IMMUNOLOGY

Liver Cancer Stem Cells as an Important Target in Liver Cancer Therapies

(2012) Gang-Ming Zou   Anti-Cancer Agents in Medicinal Chemistry

PF-03475952: a potent and neutralizing fully human anti-CD44 antibody for therapeutic applications in inflammatory diseases

(2010) Herbert A. Runnels et al.   ADVANCES IN THERAPY

A Novel Flow Cytometric Antibody Panel for Distinguishing Burkitt Lymphoma From CD10+ Diffuse Large B-Cell Lymphoma

(2010) Stephanie D. Schniederjan et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Reduction of Hyaluronan-CD44–Mediated Growth, Migration, and Cisplatin Resistance in Head and Neck Cancer Due to Inhibition of Rho Kinase and PI-3 Kinase Signaling

(2010) Carlos Torre et al.   ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY

Galectin-9 induces osteoblast differentiation through the CD44/Smad signaling pathway

(2010) Rena Tanikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An evidence for adhesion-mediated acquisition of acute myeloid leukemic stem cell-like immaturities

(2010) Keiji Funayama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CD44 activation in mature B-cell malignancies by a novel recurrent IGH translocation

(2010) X.-T. Hu et al.   BLOOD

Stable alterations of CD44 isoform expression in prostate cancer cells decrease invasion and growth and alter ligand binding and chemosensitivity

(2010) Kui Yang et al.   BMC CANCER

Inhibition of cell proliferation by CD44: Akt is inactivated and EGR-1 is down-regulated

(2010) L.-S. Zhang et al.   CELL PROLIFERATION

Colon Cancer Stem Cells: Promise of Targeted Therapy

(2010) Matilde Todaro et al.   GASTROENTEROLOGY

CD44 Regulates Survival and Memory Development in Th1 Cells

(2010) Bas J.G. Baaten et al.   IMMUNITY

Hydrotropic hyaluronic acid conjugates: Synthesis, characterization, and implications as a carrier of paclitaxel

(2010) Gurusamy Saravanakumar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion

(2010) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HGF-Promoted Motility in Primary Human Melanocytes Depends on CD44v6 Regulated via NF-kappa B, Egr-1, and C/EBP-beta

(2010) Sabine Damm et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD44-ligation induces, through ERK1/2 pathway, synthesis of cytokines TNF-α and IL-6 required for differentiation of THP-1 monoblastic leukemia cells

(2010) S Bourcier et al.   LEUKEMIA

PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells

(2010) Tong Zhang et al.   Molecular Cancer

CD44 interacts directly with Lck in a zinc-dependent manner

(2010) Dennis C. Lefebvre et al.   MOLECULAR IMMUNOLOGY

Benzo[a]pyrene treatment leads to changes in nuclear protein expression and alternative splicing

(2010) Chunlan Yan et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Osteopontin-mediated enhanced hyaluronan binding induces multidrug resistance in mesothelioma cells

(2010) K Tajima et al.   ONCOGENE

Two-State Conformations in the Hyaluronan-Binding Domain Regulate CD44 Adhesiveness under Flow Condition

(2010) Shinji Ogino et al.   STRUCTURE

Characteristic Expression Patterns of TCL1, CD38, and CD44 Identify Aggressive Lymphomas Harboring a MYC Translocation

(2009) Scott J. Rodig et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Hematopoiesis-dependent expression of CD44 in murine hepatic progenitor cells

(2009) Shinya Ohata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis

(2009) M. Tremmel et al.   BLOOD

Rheostatic signaling by CD44 and hyaluronan

(2009) Ellen Puré et al.   CELLULAR SIGNALLING

The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module

(2009) Shin-ichi Terawaki et al.   EMBO JOURNAL

Coexpression of CD44 variant isoforms and receptor for hyaluronic acid−mediated motility (RHAMM, CD168) is an International Prognostic Index and C-MYC gene status−independent predictor of poor outcome in diffuse large B-cell lymphomas

(2009) Sabine Nagel et al.   EXPERIMENTAL HEMATOLOGY

Radiation Dosimetry of 89Zr-Labeled Chimeric Monoclonal Antibody U36 as Used for Immuno-PET in Head and Neck Cancer Patients

(2009) P. K.E. Borjesson et al.   JOURNAL OF NUCLEAR MEDICINE

Involvement of CD44 in mast cell proliferation during terminal differentiation

(2009) Hirotsugu Takano et al.   LABORATORY INVESTIGATION

Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors

(2009) S. Grosso et al.   MOLECULAR CANCER THERAPEUTICS

Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS

(2009) Jun Muto et al.   MOLECULAR IMMUNOLOGY

CD44-Targeted Microparticles for Delivery of Cisplatin to Peritoneal Metastases

(2009) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis

(2009) K. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breast cancer stem cells

(2009) Kazuharu Kai et al.   Breast Cancer

 4 1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells

(2008) J. Redondo-Munoz et al.   BLOOD

TIMP1 induces CD44 expression and the activation and nuclear translocation of SHP1 during the late centrocyte/post-germinal center B cell differentiation

(2008) Young-Sik Kim et al.   CANCER LETTERS

Osteopontin: Role in immune regulation and stress responses

(2008) Kathryn X. Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD44 and hyaluronan engagement promotes dexamethasone resistance in human myeloma cells

(2008) Chikako Ohwada et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

HyaluronanCD44 pathway regulates orientation of mitotic spindle in normal epithelial cells

(2008) Takeshi Fujiwara et al.   GENES TO CELLS

Structural Basis for CD44 Recognition by ERM Proteins

(2008) Tomoyuki Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD44-Epidermal Growth Factor Receptor Interaction Mediates Hyaluronic Acid-promoted Cell Motility by Activating Protein Kinase C Signaling Involving Akt, Rac1, Phox, Reactive Oxygen Species, Focal Adhesion Kinase, and MMP-2

(2008) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic Cancer Stem Cells

(2008) Cheong J. Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

CD44 promotes progenitor homing into the thymus and T cell maturation

(2008) M. Rajasagi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expression of CD44, but not CD44v6, predicts relapse in children with B cell progenitor acute lymphoblastic leukemia lacking adverse or favorable genetics

(2008) Naveed I. Khan et al.   LEUKEMIA & LYMPHOMA

Involvement of CD44, a molecule with a thousand faces, in cancer dissemination

(2008) David Naor et al.   SEMINARS IN CANCER BIOLOGY