Article
Health Care Sciences & Services
Ji-Hoon Sim, Soo-Ho Lee, Ji-Wan Kim, Won-Uk Koh, Hyung-Tae Kim, Young-Jin Ro, Ha-Jung Kim
Summary: The study found that PLVI was significantly associated with mortality after hip fracture surgery, with low PLVI being linked to higher mortality rates. Therefore, PLVI might be an independent predictor of mortality in elderly patients undergoing hip fracture surgery.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Medicine, General & Internal
Arpit Jain, Amit Saoji
Summary: This article discusses a case of a 19-year-old boy with Scheuermann's disease, including symptoms and the diagnosis and treatment steps taken by doctors.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Clinical Neurology
Tianyuan Zhang, Shibin Shu, Wenting Jing, Qi Gu, Zezhang Zhu, Zhen Liu, Yong Qiu, Xu Sun, Bin Wang, Hongda Bao
Summary: The study aimed to validate the predictability of the S-line in Lenke 5C patients, and found that the modified S-line + is a validated risk factor for post-operative coronal decompensation in Lenke 5C AIS patients. Selecting the UIV at one level caudal to UEV could be a potential solution.
EUROPEAN SPINE JOURNAL
(2021)
Article
Orthopedics
Hakan Serhat Yanik, Ismail Emre Ketenci, Sevki Erdem
Summary: This study compared the radiologic and functional outcomes of Lenke type 3C and 6C adolescent idiopathic scoliosis patients according to distal fusion level. It found that in TL/L curves with L4 as LEV, satisfactory results can be achieved with stopping the fusion at L3, if a proper disc alignment below LIV can be obtained intraoperatively. The higher amount of LIV disc angle in the L3 group did not cause coronal and sagittal imbalance.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Article
Multidisciplinary Sciences
Laura Marie-Hardy, Lotfi Slimani, Giulia Messa, Zaineb El Bourakkadi, Annick Prigent, Celia Sayetta, Fanny Koeth, Hugues Pascal-Moussellard, Claire Wyart, Yasmine Cantaut-Belarif
Summary: Scheuermann's disease is a common spine deformity in humans, with an unclear cause. Recent genetic studies in zebrafish have identified new mechanisms linked to Scheuermann's disease, involving the Reissner fiber and ciliary beating. However, the relevance of the sensory functions of CSF-cNs for human spine disorders is still unknown.
SCIENTIFIC REPORTS
(2023)
Article
Anatomy & Morphology
Kevin M. Serra, Christina Vyzas, Sarah Shehreen, Iris Chipendo, Katherine M. Clifford, Daniel W. Youngstrom, Stephen H. Devoto
Summary: This study investigates the relationship between embryonic segmentation and adult vertebral morphology using zebrafish models. The authors induce border defects using heat stress and misregulation of segmentation genes, and find correlations between specific embryonic border defects and specific vertebral defects in population and individual studies. The data suggests that segment borders play a dominant role in vertebral development by controlling length, position, fusion, and division of vertebrae and ribs.
DEVELOPMENTAL DYNAMICS
(2023)
Article
Clinical Neurology
Xiaodong Qin, Yong Qiu, Zhong He, Rui Yin, Zhen Liu, Zezhang Zhu
Summary: This study aimed to determine the validity of selecting the last substantially touching vertebra one level proximal to last (LSTV-1) as the lowest instrumented vertebra (LIV). It was found that good outcomes can still be achieved in certain cases when LSTV-1 is selected as LIV. Risk factors for distal adding-on were also identified, including skeletal immaturity, longer thoracic curve length, preoperative coronal imbalance, and larger rotation and deviation of LSTV-1.
Article
Orthopedics
Tomohiro Yamada, Tomohiko Hasegawa, Yu Yamato, Go Yoshida, Tomohiro Banno, Hideyuki Arima, Shin Oe, Yuki Mihara, Hiroki Ushirozako, Koichiro Ide, Yuh Watanabe, Keiichi Nakai, Kenta Kurosu, Yukihiro Matsuyama
Summary: This study aimed to evaluate the accuracy of pedicle screw placement in degenerative scoliosis surgery and found an association between misplaced screws and lumbar coronal curve. Special attention should be given to the transitional vertebra of the lumbar curve.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2023)
Review
Clinical Neurology
Qingshan Li
Summary: This meta-analysis demonstrates similar treatment effects between anterior-posterior (AP) combined procedures and posterior-only (PO) procedures in correcting Scheuermann's kyphosis, with the advantage of PO procedures being less blood loss and shorter surgical duration. However, the limitations of existing data prevent conclusive results regarding postoperative complications like proximal junctional kyphosis (PJK) and distal junctional kyphosis (DJK).
PAIN RESEARCH & MANAGEMENT
(2021)
Article
Orthopedics
Wenbin Hua, Zhiwei Liao, Wencan Ke, Shuai Li, Xiaobo Feng, Bingjin Wang, Kun Wang, Xinghuo Wu, Yukun Zhang, Yong Gao, Li Ling, Cao Yang
Summary: This study evaluated the incidence and risk factors of postoperative distal adding-on in patients with Lenke 5C AIS. The postoperative TL/L curve, LIV translation, LIV + 1 translation, and postoperative coronal imbalance were determined as risk factors for postoperative distal adding-on. Moreover, selecting LBTV-1 or LSTV-1 as the LIV may increase the risk of postoperative distal adding-on.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Clinical Neurology
Do-Hyoung Kim, Seung-Jae Hyun, Chang-Hyun Lee, Ki-Jeong Kim
Summary: This study aimed to determine whether the last touched vertebra on supine radiographs is suitable for the lower instrumented vertebra in adolescent idiopathic scoliosis correction surgery. The results showed that selecting the last touched vertebra on supine radiographs as the lower instrumented vertebra yielded similar postoperative radiographic and clinical outcomes compared to selecting the last touched vertebra on upright radiographs.
Review
Medicine, General & Internal
Fu-Jun Luan, Jun Zhang, Kin-Cheung Mak, Zhi-Heng Liu, Hai-Qiang Wang
Summary: Modern medical imaging technology has benefits for disease diagnosis and treatment, but radiation exposure can increase cancer risks, especially for AIS patients who undergo repeated imaging. Using low radiation imaging modalities and PA projection techniques can reduce radiation doses and minimize radiation harms effectively.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Orthopedics
Xiangyu Hou, Zhuoran Sun, Weishi Li, Hui Wang, Lin Zhuo, Lei Yuan, Yan Zeng, Linyao Ding, Ze Chen
Summary: Selection of UIV not lower than the first coronal reverse vertebra (FCRV) can significantly reduce the risk of postoperative proximal adjacent segment degeneration (pASD) in patients with degenerative lumbar scoliosis (DLS), but the degree of Hounsfield unit (HU) asymmetry can vary among patients, indicating the need for more individualized UIV selection criteria.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Hao Cheng, Zi-Ang Jiang, Liang Chen, Guo-Dong Wang, Xiao-Yang Liu, Jian-Min Sun, Tsung-Yuan Tsai
Summary: TLK has impacts on gait, as shown by this study involving twenty patients with TLK secondary to Scheuermann's disease and twenty asymptomatic participants. The TLK group exhibited shorter stride length, longer stride time, slower gait speed, and smaller joint movement ranges compared to the control group. These abnormal gait features may exacerbate degenerative progress of lower extremity joints and serve as a guideline for physicians to focus on TLK in these patients.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Clinical Neurology
Ping-Yeh Chiu, Fu-Cheng Kao, Ming-Kai Hsieh, Tsung-Ting Tsai, Wen-Jer Chen, Chi-Chien Niu, Po-Liang Lai
Summary: Among patients with osteoporotic vertebral compression fractures (OVCFs) who underwent vertebral cement augmentation, the incidence of further fractures in sandwich vertebrae is not higher compared to adjacent vertebrae. Male gender was identified as a potential risk factor for sandwich vertebral fractures. Patients with sandwich vertebral fractures may be more likely to pursue surgical intervention than those with only adjacent fractures.
Article
Clinical Neurology
Ella Virkki, Milja Holstila, Terhi Kolari, Markus Lastikka, Kimmo Mattila, Sari Malmi, Olli Pajulo, Ilkka Helenius
Summary: This study compared the outcomes of using a hard brace versus an elastic lumbar support in treating pediatric spondylolysis, and found no significant difference in bony union or health-related quality of life between the two treatment groups.
Article
Orthopedics
Johanna Syvanen, Willy Serlo, Jenni Jalkanen, Ia Kohonen, Arimatias Raitio, Yrjana Nietosvaara, Ilkka Helenius
Summary: This study compared the recurrence rate of benign bone cysts in children treated with allograft or bioactive glass. The results showed that both treatment options provided similar outcomes in terms of recurrence and complications.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Article
Pediatrics
Pawel Grabala, Kinga Danowska-Idziok, Ilkka J. Helenius
Summary: A case of Horner's syndrome occurred in a five-year-old child after spinal correction surgery for congenital kyphoscoliosis. The syndrome was caused by disruption of the sympathetic nerve pathway. The symptoms resolved and the patient fully recovered four years post-surgery.
Article
Pediatrics
Pawel Grabala, Ilkka J. Helenius, Jacob M. Buchowski, Suken A. Shah
Summary: This study aimed to evaluate the treatment outcomes of severe idiopathic scoliosis (IS) and hypothesized that surgical treatment would have a superior impact on the health-related quality of life (HRQoL), pulmonary function (PF), back pain, and sexual function. The results showed that surgical treatment could safely correct the deformity, significantly improve respiratory function, and have significant improvements in quality of life outcome scores, back pain, and sexual function.
Article
Orthopedics
Venla Soini, Johanna Syvanen, Linda Helenius, Arimatias Raitio, Ilkka Helenius
Summary: This study aimed to assess the impact of spinal fusion on health-related quality of life (HRQoL) in patients with progressive neuromuscular scoliosis (NMS). The results showed that spinal fusion significantly improved HRQoL in NMS patients, and the extent of improvement was comparable to that in patients with adolescent idiopathic scoliosis (AIS).
Article
Orthopedics
Kaj Zilliacus, Yrjana Nietosvaara, Ilkka Helenius, Topi Laaksonen, Matti Ahonen, Petra Grahn
Summary: The risk of fracture-related nerve injury in children with forearm fractures is low and has a good potential for spontaneous recovery. All permanent nerve injuries were associated with open fractures or complications of internal fixation.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Article
Orthopedics
Hermanni Haapala, Susanna Heiskanen, Johanna Syvanen, Arimatias Raitio, Linda Helenius, Matti Ahonen, Elias Diarbakerli, Paul Gerdhem, Ilkka Helenius
Summary: Surgery for congenital spinal anomalies improves spinal deformities and health-related quality of life, but pain and function outcomes are still lower compared to healthy controls.
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2023)
Article
Clinical Neurology
Matti Ahonen, Johanna Syvanen, Linda Helenius, Mikko Mattila, Tanja Perokorpi, Elias Diarbakerli, Paul Gerdhem, Ilkka Helenius
Summary: This study aimed to evaluate pain and health-related quality of life (HRQoL) in surgically managed patients with a minimum follow-up of 10 years compared with patients with untreated adolescent idiopathic scoliosis (AIS) and a healthy control group. The results showed that patients undergoing surgery had better HRQoL than untreated patients with AIS, but still lower than healthy controls.
Review
Orthopedics
O. Pakarinen, V. Ponkilainen, M. Uimonen, M. Haapanen, I. Helenius, I. Kuitunen
Summary: This study aimed to analyze whether adding risk-based criteria to clinical examination-based selective ultrasound screening would increase the rates of early detected cases of developmental dysplasia of the hip (DDH) and decrease the rate of late detected cases. A systematic review with meta-analysis was conducted and it was found that using risk factors in conjunction with clinical examination in the selective ultrasound screening of DDH might lead to fewer operatively treated cases. However, more studies are needed for stronger conclusions.
BONE & JOINT JOURNAL
(2023)
Article
Medicine, General & Internal
Pawel Grabala, Ilkka J. Helenius, Piotr Kowalski, Michal Grabala, Slawomir Zacha, Jaroslaw M. Deszczynski, Tomasz Albrewczynski, Michael A. Galgano, Jacob M. Buchowski, Kelly Chamberlin, Suken A. Shah
Summary: This study evaluated the safety and accuracy of pedicle screw placement in children with spinal deformities using postoperative CT scans. The results showed that 98% of screws were accurately placed and no complications associated with screw insertion were observed.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Venla Soini, Johanna Syvanen, Ilkka Helenius, Linda Helenius, Arimatias Raitio
Summary: Progressive scoliosis can lead to extensive spinal fusion surgery with a risk of significant bleeding. This study investigated the risk factors for blood loss related to pedicle screw instrumentation in adolescent idiopathic scoliosis (AIS) and neuromuscular scoliosis (NMS) patients. The analysis found that levels fused, operative time, and erythrocyte size were correlated with perioperative blood loss in both AIS and NMS groups. Additionally, male sex and osteotomy number were associated with more drain output in AIS patients, while fused levels were correlated with drain output in NMS patients.
Article
Pediatrics
Pawel Grabala, Ilkka J. Helenius, Kelly Chamberlin, Michael Galgano
Summary: Early-onset scoliosis (EOS) is a spinal deformity diagnosed before the age of ten, and surgical treatment should be considered when the curvature exceeds a certain degree. Magnetically controlled growing rods (MCGRs) offer a safe and effective option for treating EOS, allowing for non-invasive correction of spinal deformity and controlling spine growth and curvature while minimizing hospitalizations and anesthesia.
Review
Surgery
Arimatias Raitio, Antti J. Saarinen, Juha-Jaakko Sinikumpu, Ilkka Helenius
Summary: Biomaterials are widely used in orthopedic surgery to aid in bone healing and repair. There are a variety of biomaterials available, each with their own bioactive properties. Despite the increasing number of studies, there is still a lack of randomized controlled trials in this field. Most studies have found that biomaterials are suitable treatment options for various indications, but some don't perform as well as expected and are not recommended for clinical use.
SCANDINAVIAN JOURNAL OF SURGERY
(2023)
Article
Medicine, General & Internal
Pawel Grabala, Ilkka J. Helenius, Michal Grabala, Suken A. Shah
Summary: This study evaluates the effect and safety of using pedicle screws to increase the diameter of the vertebral pedicles in children with spinal deformities. The results show that the larger the diameter of the screw, the greater the expansion of the pedicle, and there is a low risk of lateral or medial breaches without increased complications. Preoperative MRI measurements of the pedicles can help with preoperative planning.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Pawel Grabala, Kelly Chamberlin, Michal Grabala, Michael A. Galgano, Ilkka J. Helenius
Summary: This study compared the differences between the use of preoperative Halo Gravity Traction and the use of a Magnetically Controlled Growing Rod as a temporary internal distraction device. The results showed that using preoperative Halo Gravity Traction may be safer and achieve similar treatment outcomes as using a Magnetically Controlled Growing Rod in the management of neglected scoliosis.
JOURNAL OF CLINICAL MEDICINE
(2023)
