Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume 64, Issue 12, Pages 611-619Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2014.996710
Keywords
Biodegradable; bioinspired polyurethane; chlorogenic acid; tissue adhesive
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Funding
- Scientific and Technical Research Council of Turkey [TUBITAK-TBAG-111T104]
- Scientific Research Fund of Inonu University [IUBAP-2013/71]
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Highly adhesive bioinspired polyurethanes (PUs) based on the chlorogenic acid (CLA) were prepared from 4,4'-methylenebis (cyclohexyl isocyanate) (MCI) and polyethylene glycol 200 (PEG 200). The polyurethanes exhibited the lowest glass transition temperature (T-g), improved thermal stability and good adhesive properties. The highest adhesion strength was found as 373.3 +/- 47.5 kPa for 10% CLA containing PUs. The polyurethanes were observed to be biodegradable and were in the range of 19-24% for 8 weeks as depending on chlorogenic acid containing of PUs. As a result, prepared biocompatible-adhesive bioinspired polyurethanes are good candidates for medical applications as a tissue adhesive material. [GRAPHICS] .
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