Article
Biotechnology & Applied Microbiology
Peipei Ma, Enpeng Liu, Zhirui Zhang, Tao Li, Zijian Zhou, Wen Yao, Jiafa Chen, Jianyu Wu, Yufang Xu, Huiyong Zhang
Summary: Through a genome-wide association study, we identified two single nucleotide polymorphisms (SNPs) in the ZmWAX2 gene that are associated with quantitative resistance to F. verticillioides in maize. The absence of ZmWAX2 compromises resistance to multiple diseases caused by F. verticillioides, while overexpression of ZmWAX2 increases immunity. These findings suggest that ZmWAX2 could be a valuable target for developing F. verticillioides-resistant maize varieties.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Article
Plant Sciences
Yufang Xu, Renjie Wang, Peipei Ma, Jiansheng Cao, Yan Cao, Zijian Zhou, Tao Li, Jianyu Wu, Huiyong Zhang
Summary: In this study, a novel miRNA, zma-unmiR4, was discovered in maize that responds to Fusarium verticillioides. This miRNA balances maize growth and resistance to F. verticillioides by modulating the expression of its target gene, ZmGA2ox4. Additionally, the miRNA affects plants' defense response by regulating the accumulation of bioactive gibberellin and perturbing the expression of a set of defense-related genes.
MOLECULAR PLANT PATHOLOGY
(2022)
Article
Food Science & Technology
Qi Deng, Hanxiang Wu, Qin Gu, Guangfei Tang, Wende Liu
Summary: The family 2 glycosyltransferase FvCpsA in F. verticillioides plays a critical role in fungal growth, FB1 biosynthesis, and virulence. Its deletion leads to significant defects in vegetative growth, increased resistance to stress agents, and upregulation of FB1 production. Interestingly, FvCpsA is essential for penetration and pathogenicity, highlighting its importance in the pathogenicity of F. verticillioides.
Article
Microbiology
Ning Liu, Yue Chen, Jing Liu, Qianfu Su, Bin Zhao, Manli Sun, Hui Jia, Zhiyan Cao, Jingao Dong
Summary: This study investigated the effects of temperature on the growth and pathogenicity of F. verticillioides and F. graminearum. The results showed that these two fungal pathogens have different adaptability to different temperatures. RNA-seq analysis revealed distinct gene expression patterns in growth and metabolic pathways under different temperatures for both species.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Food Science & Technology
Zehua Zhou, Jie Liu, Jie Zhang, Huijuan Yan, Tuyong Yi, Won Bo Shim
Summary: The LxxLL motif of the Med1 transcriptional coactivator regulates the biosynthesis of key substances, such as starch and carotenoid, which in turn affects the production of fumonisin B1 (FB1) in the mycotoxigenic fungus Fusarium verticillioides.
Article
Genetics & Heredity
Alessandra Lanubile, Virginia Maria Grazia Borrelli, Mario Soccio, Paola Giorni, Lorenzo Stagnati, Matteo Busconi, Adriano Marocco
Summary: The study investigated the functional characterization of the ZmLOX4 gene to uncover its strategic role in maize resistance against Fusarium verticillioides, as well as its influence on the expression of several LOX, jasmonic acid (JA) and green leaf volatiles (GLV) genes. The results suggest that ZmLOX4 plays a crucial role in controlling defense against F. verticillioides and modulating the expression of key genes involved in plant defense mechanisms.
Article
Food Science & Technology
Chenjie Yu, Xin Liu, Xinyue Zhang, Mengxuan Zhang, Yiying Gu, Qurban Ali, M. Sherif Ramzy Mohamed, Jianhong Xu, Jianrong Shi, Xuewen Gao, Huijun Wu, Qin Gu
Summary: The lipopeptide mycosubtilin from Bacillus subtilis ATCC6633 showed significant inhibition of F. graminearum and F. verticillioides growth in vitro, as well as control of adverse effects on wheat and maize in planta experiments. It decreased mycotoxin production in infected grains and downregulated genes involved in mycotoxin biosynthesis, indicating its potential as a biological agent for controlling plant diseases and Fusarium toxin contamination.
Article
Agronomy
Kamal A. M. Abo-Elyousr, Maged M. Saad, Adel D. Al-Qurashi, Omer H. M. Ibrahim, Magdi A. A. Mousa
Summary: Brevibacillus parabrevis and Pseudomonas fluorescens show potential as biocontrol agents against Fusarium wilt in cumin.
Article
Multidisciplinary Sciences
Gang Yao, Weikai Chen, Jie Sun, Xiangfeng Wang, Huan Wang, Tan Meng, Lili Zhang, Li Guo
Summary: We successfully assembled a gap-free genome of F. verticillioides, a filamentous fungus, using PacBio HiFi data and high-throughput chromosome capture (Hi-C) sequencing data. The assembled sequence of 42.0 Mb contains eleven chromosomes with complete centromeres and 19 out of 22 telomeres. This genome assembly shows significant improvements in contiguity, completeness, and correctness compared to previous versions.
Article
Plant Sciences
Xuanjun Feng, Hao Xiong, Dan Zheng, Xiaobing Xin, Xuemei Zhang, Qingjun Wang, Fengkai Wu, Jie Xu, Yanli Lu
Summary: This study identified favorable alleles for Fusarium ear rot (FER) resistance in the wild-type species of maize, teosintes. The resistance was found to be positively correlated with grain yield. Several coincident and synergistic QTLs associated with FER resistance and yield traits were identified, providing the possibility of breeding FER resistant maize cultivars without reducing yield.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Chandan Sarkar, Sarmin Jamaddar, Tawhida Islam, Milon Mondal, Muhammad Torequl Islam, Mohammad S. Mubarak
Summary: Thymoquinone (TQ) is a natural compound extracted from the black angular seeds of Nigella sativa, with various pharmacological activities that can be used in the prevention and treatment of multiple diseases. Research has shown that TQ exhibits antioxidant, anti-inflammatory, cardioprotective, hepatoprotective, antidiabetic, neuroprotective, and anticancer properties.
Article
Biotechnology & Applied Microbiology
Mei Lin, Yakubu Saddeeq Abubakar, Lijing Wei, Jiajia Wang, Xiange Lu, Guodong Lu, Zonghua Wang, Jie Zhou, Wenying Yu
Summary: This study explored the regulatory role and biological functions of the components of the PTS2 receptor complex in Fusarium verticillioides. The study found that FvPex7 directly interacts with FvPex20 and that the peroxisome localization of PTS2-containing proteins is determined by Pex20. Additionally, the study observed that mutants of the PTS2 receptor complex showed reduced pathogenicity and FB1 biosynthesis.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jing Guo, Xiuli Song, Rongxing Li, Qi Zhang, Shengwei Zheng, Qiucheng Li, Bo Tao
Summary: Glyphosate-resistant fungus Fusarium verticillioides was found and characterized in this study. It could grow in a medium containing glyphosate and its epsps gene was cloned, which showed low expression levels and belonged to class I genes naturally sensitive to glyphosate. Additionally, the strain C-2 was highly effective in degrading glyphosate and could be potentially used for bioremediation of contaminated soil.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2022)
Article
Agronomy
Davide Ferrigo, Massimiliano Mondin, Alessandro Raiola
Summary: The commercial and sanitary qualities of cereals determine the final application and destination of the grain. The cultivation area of sorghum has been increasing in Italy and is often adjacent to maize fields, leading to the risk of sharing mycotoxigenic fungi such as Fusarium verticillioides. This study explores the commonalities and differences in fungal physiology and plant growth parameters between F. verticillioides strains from maize and sorghum.
Article
Genetics & Heredity
Chunxia Ge, Changxiao Tang, Yu-Xiu Zhu, Guan-Feng Wang
Summary: Through genome-wide analysis, 103 putative 2OGD genes were identified in maize and divided into three classes - DOXA, DOXB, and DOXC. Among these genes, ACO, F3H, and NCS encoding three 2OGD proteins were induced by Fusarium verticillioides and Fusarium graminearum. The two transcription factors ZmDOF and ZmHSF may also be involved in resistance to these two pathogens.
Article
Multidisciplinary Sciences
Ghulam Muhammad, Abdul Manaf, Fayyaz-ul-Hassan, Azeem Khalid, Ahmad Sher, Carol J. Lovatt, Asad Syed, Ali H. Bahkali, Abdallah M. Elgorban, Abdul Qayyum
Summary: This study assessed the effects of suitable sowing dates on the growth and yield of Sinapis alba and conducted experiments at three locations in Pakistan. The results showed that the sowing date of October 15 achieved the best growth and yield performance, with the SAWCRI location exhibiting the highest yield. This indicates the significant importance of optimal sowing dates for crop productivity and improving farmers' livelihoods.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Chemistry, Inorganic & Nuclear
B. Shruthi, Hosakere D. Revanasiddappa, B. Jayalakshmi, Asad Syed, Abdallah M. Elgorban, Rajalakshmanan Eswaramoorthy, Raghavendra G. Amachawadi, Chandan Shivamallu, Shiva Prasad Kollur
Summary: The work presented here focuses on the preparation and characterization of an imine-based fluorescent on-off sensor probe, EHBA. The probe demonstrated selective detection capability towards Cu2+ ions, with a visually observable color change in the presence of Cu2+. Additionally, the probe exhibited an outstanding sensitivity and selectivity towards Cu2+ ions, while remaining unchanged in the presence of other various metal ions.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Environmental Sciences
B. Janani, R. Balakrishnaraja, Abdalla M. Elgorban, Ali H. Bahkali, Rajender S. Varma, Asad Syed, S. Sudheer Khan
Summary: A novel ZnS-Cu7S4 nanohybrid supported on chitosan matrix was fabricated using the sonochemical method. The nanohybrid exhibited excellent photocatalytic performance due to the co-existence of ZnS and Cu7S4, with the addition of vacancy sites in ZnS promoting visible light response and charge transport/separation. The ZnS-Cu7S4/Chitosan showed potential for the photodegradation of p-chlorophenol under visible-light irradiation, and in vitro cytotoxicity studies confirmed its non-toxicity and promising remediation applications.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Chemistry, Multidisciplinary
P. R. Sivaranjani, Asad Syed, Abdallah M. Elgorban, Ali H. Bahkali, R. Balakrishnaraja, Rajender S. Varma, S. Sudheer Khan
Summary: The current study presents the design of a novel photocatalyst, which utilizes a heterojunction to capture a broad solar spectrum and effectively separate photogenerated charge carriers. A nano-heterojunction of a-Fe2O3 and b-La2S3 on cubic CoCr2O4 spinel was fabricated using ultrasonication-assisted co-precipitation method. Extensive characterization using various techniques confirmed the superior photodegradation performance of the CoCr2O4/a-Fe2O3/b-La2S3 (CFL) catalyst, achieving a 92.83% degradation of doxycycline (DOX) under visible light. The study also investigated the factors influencing the photodegradation process and proposed a possible photocatalytic mechanism of CFL for DOX degradation.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2023)
Article
Agricultural Engineering
Quanguo Zhang, Jiabin Yang, Tian Zhang, Xuenan Shui, Huan Zhang, Zhou Chen, Xun He, Tingzhou Lei, Danping Jiang, Abdallah M. Elgorban, Asad Syed, Manoj Kumar Solanki
Summary: Ultrasonication assisted ionic liquid pretreatment was applied to enhance photo-fermentative biohydrogen production from Arundo donax L. biomass. The optimal conditions were found to be 16 g/L of 1-Butyl-3-methylimidazolium Hydrogen Sulfate ([Bmim]HSO4) combined with ultrasonication at a solid to liquid ratio (SLR) of 1:10 for 1.5 h under 60 °C. The maximum delignification achieved was 22.9%, and the hydrogen yield and energy conversion efficiency were increased by 1.5-fold and 46.4% (p < 0.05), respectively, compared to untreated biomass. Heat map analysis indicated that pretreatment temperature had the strongest correlation with hydrogen yield.
BIORESOURCE TECHNOLOGY
(2023)
Article
Energy & Fuels
Sonia Kiran, Sara Houda, Ghazala Yasmin, Zahid Shafiq, Amir Abbas, Sumaira Manzoor, Asad Syed, Abdallah M. Elgorban, Nouf S. S. Zaghloul, Muhammad Naeem Ashiq
Summary: A unique MOF derived nanocomposite as an electrocatalyst with ultrahigh functionality and extremely low overpotential for catalytic OER was reported.
Article
Multidisciplinary Sciences
Azhar Sohail Shahzad, Uzma Younis, Nargis Naz, Subhan Danish, Asad Syed, Abdallah M. Elgorban, Rajalakshmanan Eswaramoorthy, Shoucheng Huang, Martin Leonardo Battaglia
Summary: Lead (Pb) toxicity is a significant environmental issue, and acidified biochar has shown promise as an effective management technology for mitigating Pb toxicity. This study explores the potential of acidified biochar as a low-cost and eco-friendly method for managing Pb-contaminated soils, with promising results in alleviating Pb stress in mint.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Mubashar Hussain, Farwa Hameed, Kiran Aftab, Riffat Iqbal, Neelam Arif, Moazama Batool, Razia Iqbal, Shahzad Toufeeq, Asad Syed, Abdallah M. Elgorban, Rajalakshmanan Eswaramoorthy
Summary: This study found that the edible grasshopper Poikelocercus pictus could serve as a protein source in poultry feed, and it had positive effects on the growth and feed intake of Rhode Island Red chicken.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Safi Ullah Khan, Faizan Ullah, Masroor Hussain, Muhammad Zahid Ihsan, Sultan Mehmood, Liaqat Ali, Shah Saud, Shah Fahad, Shah Hassan, Muhammad Zeeshan, Sultan Akbar Jadoon, Asad Syed, Abdallah M. Elgorban, Rajalakshmanan Eswaramoorthy, Muhammad Iftikhar Hussain
Summary: The phytochemicals found in Chenopodium glaucum extracts were highly phytotoxic on radish seed germination and seedling growth. It is recommended to isolate and characterize these novel compounds for the development of new biodegradable herbicides.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Mohamed A. Abdel-Wahab, Abdallah M. Elgorban, Ali H. Bahkali
Summary: This study aims to explore the abilities of microbes from mangroves in Saudi Arabia to produce high levels of lipids. A total of 961 isolates of yeasts and filamentous fungi were isolated from various submerged marine samples collected from different mangrove sites. The results showed that two oleaginous yeasts and four Aurantiochytrium strains from mangroves in Saudi Arabia could produce high levels of lipids.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Kamran Azeem, Farah Inamullah, Farah Naz, Faisal Nadeem, Hafiz Muhammad Jhanzab, Ahmad Sher, Yamin Bibi, Asad Syed, Ali H. Bahkali, Abdallah M. Elgorban, Mubashar Hussain, Abdul Qayyum
Summary: In this study, the researchers evaluated the impact of combining organic and inorganic nitrogen sources and beneficial micro-organisms on maize's nitrogen uptake, N use efficiency, and N utilization efficiency. The results showed that the combination of organic fertilizer (FYM) and inorganic nitrogen (50:50) with the application of beneficial micro-organisms significantly increased total nitrogen uptake, N utilization efficiency, stover grain, and grain protein. The highest nitrogen uptake and protein contents were observed with the application of 150 kg N ha-1. Applying 100 kg N ha-1 resulted in the highest N use efficiency and N utilization efficiency. Overall, an N application level of 100 kg N ha-1, beneficial micro-organisms, and a 50:50 ratio of inorganic and organic nitrogen proved to be effective in enhancing the N use efficiency and grain quality of maize.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2023)
Article
Environmental Sciences
Kumar Manimaran, Dede Heri Yuli Yanto, Chinnaperumal Kamaraj, Kumar Selvaraj, Saravanan Pandiaraj, Abdallah M. Elgorban, Shanmugam Vignesh, Haekyoung Kim
Summary: The current study developed a unique biomaterial, CuONPs, that can combat oxidative stress and microbial infections without harm. The synthesized CuONPs using Pleurotus mushroom extract are easy to make, environmentally friendly, long-lasting, and non-toxic. Characterization analysis showed a sharp absorbance peak at 250nm and a spherical structure with an average particle size of 20nm.
ENVIRONMENTAL RESEARCH
(2023)
Article
Pharmacology & Pharmacy
Abu Baker, Asad Syed, Mohamed Mohany, Abdallah M. Elgorban, Mohd Sajid Khan, Salim S. Al-Rejaie
Summary: Prostate cancer, the leading and most aggressive cancer globally, poses challenges for current therapeutic approaches. In this study, a combinatorial nanomedicine targeting prostate cancer was developed, demonstrating high safety and effectiveness.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Chemistry, Multidisciplinary
Anas Ouled Aitouna, Noureddine Mazoir, Abdellah Zeroual, Asad Syed, Ali H. Bahkali, Abdallah M. Elgorban, Meenakshi Verma, Mohammed El Idrissi, Radomir Jasinski
Summary: The application of molecular electron density theory (MEDT) in investigating the [5+2] cycloaddition reaction between oxidopyrylium and ethervinylether reveals that oxidopyrylium acts as an electrophile while ethervinylether acts as a nucleophile, based on conceptual DFT indices. Analysis of energetical parameters demonstrates that this cycloaddition reaction is both regio- and stereoselective, which is consistent with empirical observations. Through a topological analysis of the electron localization function (ELF), it is determined that this [5+2] cycloaddition occurs via a two-step, single-step mechanism along the most favored route. Additionally, docking results indicate that the (1-20) oxabicyclo[3.2.1]octene derivatives possess significant anti-HIV potential.
STRUCTURAL CHEMISTRY
(2023)
Article
Plant Sciences
Mohamed A. Abdel-Wahab, Abdallah M. Elgorban, Ali H. Bahkali
Summary: This study found that Crypthecodinium sp. AL-05 can successfully grow on macroalgal hydrolysate and can be used in industrial processes. Glucose concentration has a significant impact on the growth and lipid production of Crypthecodinium sp. AL-05, with the best results achieved at a concentration of 40 g/l. Additionally, a combination of macroalgal hydrolysate with glucose or molasses also positively affects the growth and lipid production.
