Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties

Title
Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties
Authors
Keywords
Olanzapine, Methyl-β-cyclodextrin, Inclusion complexes, Freeze drying, Supercritical carbon dioxide
Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 494, Issue 1, Pages 408-416
Publisher
Elsevier BV
Online
2015-08-25
DOI
10.1016/j.ijpharm.2015.08.062

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